The Most Unique Restaurants in San Francisco

The OpenTable Team

San Francisco offers a desirable travel destination along the California coastline, chock full of museums, scenic views and eclectic neighborhoods. Not to mention, 'Frisco has one of the most talked-about culinary scenes in the country! San Francisco's dining scene serves up everything from vegan-friendly delight and raw bars to authentic ethnic cuisine. But where are the smartest, savviest diners eating out? Welcome to the Tastemaker Lists. We’ve pulled data from thousands of restaurants to find the most unique restaurants in San Francisco according to OpenTable's most expert, seasoned diners. If in the mood for a memorable meal, check out this list of the most unique restaurants in San Francisco.

Restaurants:Guiso Latin Fusion, Terrapin Creek Cafe & Restaurant, Tisza Bistro and Bar
Price Range:$$ - $$$$
Cuisines:Latin American, Californian
Neighborhoods:Healdsburg, Bodega Bay, Windsor

Guiso Latin Fusion

$$$$·Latin American·
Healdsburg
790 reviews
  • Neighborhood Gem
  • Authentic
  • Creative Cuisine
Guiso Latin Fusion is a family owned bistro-style restaurant in the town of Healdsburg in wine country. For city folk who want a break from the city streets or travelers who are ouRead more
98% recommended
Best Overall in San Francisco Bay Area
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Terrapin Creek Cafe & Restaurant

$$$$·Californian·
Bodega Bay
1,349 reviews
  • Fit for Foodies
  • Good for a Date
  • Special Occasion
Terrapin Creek Cafe and Restaurant is a casual neighborhood spot that locals adore for its convivial atmosphere and festive energy. Located in Bodega Bay, the interior has ochre waRead more
100% recommended
Californian in San Francisco Bay Area
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Tisza Bistro and Bar

$$$$·Californian·
Windsor
486 reviews
  • Creative Cuisine
  • Neighborhood Gem
  • Casual
Tsiza Bistro and Bar sits in the heart of Sonoma’s wine country, making it an excellent place to stop when you’re out visiting vineyards near Windsor. The focus here is on ContempoRead more
94% recommended
Californian in Wine Country
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Della Fattoria

$$$$·Farm-to-table·
Petaluma
222 reviews
  • Local Ingredients
  • Fit for Foodies
  • Good for a Date
Della Fattoria is an artisan bread bakery and European style cafe located in Petaluma, California. Open for over 14 years, it has a reputation as one of the best bread bakeries in Read more
95% recommended
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Walter Hansel Wine Bistro

$$$$·French·
Santa Rosa
1,123 reviews
  • Special Occasion
  • Local Ingredients
  • Good for a Date
Located in the famed roadhouse just west of Santa Rosa, Walter Hansel Bistro is an intimate, cozy restaurant that focuses on quality and customer satisfaction. It’s a French bistroRead more
95% recommended
French in San Francisco Bay Area

Bollywood Bar & Clay Oven

$$$$·Indian·
Santa Rosa
308 reviews
  • Fit for Foodies
  • Creative Cuisine
  • Good for a Date
A night out at Bollywood Bar and Clay Oven will prove that it’s one of the most unique restaurants in San Francisco. It is in downtown Santa Rosa on Old Courthouse Square and serveRead more
89% recommended
Indian in San Francisco Bay Area
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Sazon - Santa Rosa

$$$$·Peruvian·
Santa Rosa
580 reviews
  • Casual
  • Creative Cuisine
  • Worth the Drive
Opened by father and son proprietors Juan Luis and Jose Navarro, Sazon is the most authentic and beloved Peruvian Restaurant in the area. The family takes a cue from authentic PeruRead more
91% recommended
Not available on OpenTable
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St. Francis Winery & Vineyards

$$$$·Californian·
Santa Rosa
1,361 reviews
  • Special Occasion
  • Tasting Menu
  • Notable Wine List
For a special occasion or big event, it’s great to consider some of the most unique restaurants in San Francisco where you can enjoy even more than the food! St. Francis Winery andRead more
98% recommended
Best Service in San Francisco Bay Area
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Sushi Kosho

$$$$·Sushi·
Sebastopol
146 reviews
  • Fit for Foodies
  • Good for a Date
  • Creative Cuisine
Kosho Restaurant at The Barlow is a modern Japanese and sushi restaurant in Sebastopol with a rich, warm interior that is perfect for a romantic date or a dinner with friends. The Read more
85% recommended
Sushi in San Francisco Bay Area
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Élyse Restaurant

$$$$·Contemporary French·
San Francisco Bay Area
137 reviews
  • Creative Cuisine
  • Special Occasion
  • Good for Anniversaries
Elyse is a new modern French Vietnamese restaurant located in downtown San Jose. The chic dining setting, innovative flavor combinations and eclectic wine list make it uniquely appRead more
89% recommended
Not available on OpenTable
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Albatross

$$$$·Californian·
Danville
490 reviews
  • Good for a Date
  • Great for Outdoor Dining
  • Special Occasion
Albatross is a beautiful modern restaurant with a large dining room, high ceilings and a partially open kitchen to give you a view of the chefs at work. The menu features farm-to-tRead more
84% recommended
Healthy in East Bay
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Juanita & Maude

$$$$·American·
Albany
663 reviews
  • Neighborhood Gem
  • Fit for Foodies
  • Creative Cuisine
Juanita & Maude, a neighborhood bar run by Chef Scot Eastman offers a unique spin on American cuisine. Located in Albany, in the East Bay, it’s a great escape from the bustle of doRead more
95% recommended
American in San Francisco Bay Area
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Trading Post Restaurant

$$$$·Farm-to-table·
Cloverdale
370 reviews
  • Local Ingredients
  • Creative Cuisine
  • Neighborhood Gem
Located in Cloverdale, Trading Post is a casual dining Californian restaurant that has a full bakery right at the restaurant, serving savory treats like brandied onion rolls, potatRead more
94% recommended
Best Overall in Wine Country
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Valette

$$$$·Contemporary American·
Healdsburg
2,035 reviews
  • Fit for Foodies
  • Special Occasion
  • Good for a Date
Valette is a contemporary American restaurant located in Sonoma County that locals consider to be one of the most unique restaurants in San Francisco. The kitchen here focuses on rRead more
95% recommended
Contemporary American in San Francisco Bay Area
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Da Flora

$$$$·Italian·
North Beach
158 reviews
  • Neighborhood Gem
  • Romantic
  • Good for a Date
If you’re looking for an experience that is a different speed than your average night out in town, Da Flora in one of the most unique restaurants in San Francisco to find it. Just Read more
100% recommended
Best Ambiance in San Francisco Bay Area
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Pesce e Riso

$$$$·Italian·
North Beach
243 reviews
  • Creative Cuisine
  • Fit for Foodies
  • Neighborhood Gem
Pesce E Riso is a neighborhood Italian restaurant with a Japanese twist located in the North Beach neighborhood of San Francisco. North Beach, also called Little Italy, is home to Read more
98% recommended
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Creekwood Restaurant

$$$$·Italian·
Berkeley
333 reviews
  • Neighborhood Gem
  • Fit for Foodies
  • Casual
Creekwood features a delightful California-Italian menu in a cozy, intimate space with an open kitchen and pizza oven. Located in South Berkeley, it is quickly becoming a favorite Read more
92% recommended
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Eight Tables by George Chen

$$$$·Chinese·
Chinatown
199 reviews
  • Special Occasion
  • Tasting Menu
  • Creative Cuisine
A restaurant of international fame, Eight Tables takes inspiration from the Private Chateau Cuisine dining style, which has popped up all across China. The tasting menu uses the fiRead more
92% recommended
Chinese in San Francisco Bay Area
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The Hero Ranch Kitchen

$$$$·American·
Saratoga
625 reviews
  • Great for Outdoor Dining
  • Good for a Date
  • Special Occasion
The Hero Ranch Kitchen, located in Saratoga, is the latest restaurant from Angelo Heropoulos. The eatery features eclectic French/California country decor with paneling of reclaimeRead more
95% recommended
American in San Francisco Bay Area
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PLAJ

$$$$·Scandinavian·
Civic Center / Hayes Valley / Van Ness
2,172 reviews
  • Pre/post Theatre
  • Creative Cuisine
  • Fit for Foodies
For a lovely, transportive experience, head to Plaj, the fancy Scandinavian-inspired restaurant located in the Inn at the Opera. It features a beautiful interior with only 50 seatsRead more
91% recommended
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