Best American Restaurants in Little Italy (San Diego)

Prepkitchen - Little ItalyPrepkitchen - Little Italy
(1012)
$$$$
American | Little Italy, San Diego
Booked 14 times today
WhisknladleWhisknladle
(1629)
$$$$
American | La Jolla, San Diego
Booked 31 times today
Great Maple San DiegoGreat Maple San Diego
(1474)
$$$$
American | Hillcrest, San Diego
Booked 32 times today
Prepkitchen - La JollaPrepkitchen - La Jolla
(267)
$$$$
American | La Jolla, San Diego
Booked 6 times today
The Patio on LamontThe Patio on Lamont
(1085)
$$$$
American | Pacific Beach, San Diego
Booked 18 times today
Urban SolaceUrban Solace
(1977)
$$$$
American | North Park, San Diego
Booked 19 times today
Herringbone – La JollaHerringbone – La Jolla
(1428)
$$$$
American | La Jolla, San Diego
Booked 42 times today
Farmer's Bottega RestaurantFarmer's Bottega Restaurant
(380)
$$$$
American | Mission Hills, San Diego
Booked 20 times today
George's Ocean TerraceGeorge's Ocean Terrace
(3194)
$$$$
American | La Jolla, San Diego
Booked 84 times today
1500 OCEAN at the Hotel Del Coronado1500 OCEAN at the Hotel Del Coronado
(1747)
$$$$
American | Coronado, San Diego
Booked 27 times today
Brooklyn Girl EateryBrooklyn Girl Eatery
(1025)
$$$$
American | Mission Hills, San Diego
Booked 8 times today
Firehouse American Eatery and LoungeFirehouse American Eatery and Lounge
(62)
$$$$
American | Pacific Beach, San Diego
Booked 1 time today
Searsucker Downtown San DiegoSearsucker Downtown San Diego
(2305)
$$$$
American | Downtown / Gaslamp, San Diego
Booked 53 times today
Provisional Restaurant at The Pendry HotelProvisional Restaurant at The Pendry Hotel
(54)
$$$$
American | Downtown / Gaslamp, San Diego
Booked 26 times today

Best Italian Restaurants in Little Italy (San Diego)

RovinoRovino
(115)
$$$$
Italian | Little Italy, San Diego
Booked 3 times today
Bencotto Italian KitchenBencotto Italian Kitchen
(1041)
$$$$
Italian | Little Italy, San Diego
Booked 57 times today
MonelloMonello
(666)
$$$$
Italian | Little Italy, San Diego
Booked 34 times today
Isola Pizza BarIsola Pizza Bar
(137)
$$$$
Italian | Little Italy, San Diego
Booked 4 times today
BarbusaBarbusa
(526)
$$$$
Italian | Little Italy, San Diego
Booked 39 times today
Buon AppetitoBuon Appetito
(605)
$$$$
Italian | Little Italy, San Diego
Booked 16 times today
Davanti Enoteca - Little ItalyDavanti Enoteca - Little Italy
(342)
$$$$
Italian | Little Italy, San Diego
Booked 16 times today
Civico 1845Civico 1845
(570)
$$$$
Italian | Little Italy, San Diego
Booked 17 times today
Ristorante IllandoRistorante Illando
(65)
$$$$
Italian | Little Italy, San Diego
Booked 1 time today
Baci Restaurant Baci Restaurant
(816)
$$$$
Italian | Old Town, San Diego
Booked 4 times today
Salvatore's Cucina ItalianaSalvatore's Cucina Italiana
(543)
$$$$
Italian | Downtown / Gaslamp, San Diego
Booked 12 times today
CUCINA urbanaCUCINA urbana
(4192)
$$$$
Italian | Banker's Hill, San Diego
Booked 81 times today
CataniaCatania
(416)
$$$$
Italian | La Jolla, San Diego
Booked 30 times today
Piatti - La JollaPiatti - La Jolla
(2688)
$$$$
Italian | La Jolla, San Diego
Booked 44 times today
Manhattan of La JollaManhattan of La Jolla
(616)
$$$$
Italian | La Jolla, San Diego
Booked 14 times today
Isola la JollaIsola la Jolla
(110)
$$$$
Italian | La Jolla, San Diego
Booked 6 times today
Primavera Ristorante- CoronadoPrimavera Ristorante- Coronado
(615)
$$$$
Italian | Coronado, San Diego
Booked 8 times today
Italia MiaItalia Mia
(58)
$$$$
Italian | Downtown / Gaslamp, San Diego
Booked 4 times today
de Medici Cucina Italianade Medici Cucina Italiana
(766)
$$$$
Italian | Downtown / Gaslamp, San Diego
Booked 13 times today
Piazza 1909Piazza 1909
(137)
$$$$
Italian | La Jolla, San Diego
Booked 7 times today
Bottega AmericanoBottega Americano
(635)
$$$$
Italian | Downtown / Gaslamp, San Diego
Booked 9 times today
Alexander's on 30thAlexander's on 30th
(1563)
$$$$
Italian | North Park, San Diego
Booked 13 times today

Popular restaurants in San Diego

Browse some of the most booked restaurants in San Diego

R&B Crawfish Lounge
(1)
$$$$
Seafood | Kearny Mesa
Butcher Shop Steakhouse - San Diego
(163)
$$$$
Steak | Kearny Mesa
94th Aero Squadron - San Diego
(536)
$$$$
American | Kearny Mesa
Benihana - San Diego
(185)
$$$$
Japanese | Mission Valley
True Food Kitchen - San Diego FV
(324)
$$$$
Contemporary American | Mission Valley
View all San Diego restaurants

Treat your taste buds: Explore Little Italy (San Diego) restaurants.

Little Italy (San Diego) Restaurants

The Kettle RoomThe Kettle Room
27 reviews
$$$$
Contemporary American | Little Italy, San Diego

Love the service and food. Would recommend this place to family and friends. Will be back whenever back inSan Diego. More

OpenTable Diner -
RovinoRovino
115 reviews
$$$$
Italian | Little Italy, San Diego
Booked 3 times today

Great find! We chose Rovino for a birthday celebration. Our experience was outstanding from the moment we arrived. One of the owners seated us and made wonderful suggestions about his favorites from the menu. Everything was delicious--still thinking about the Brussel sprouts appetizer! Very attentive service to make sure we were enjoying our experience. Definitely will be back. More

OpenTable Diner -
King & Queen Cantina - San DiegoKing & Queen Cantina - San Diego
21 reviews
$$$$
Mexican | Little Italy, San Diego
Booked 10 times today

As always, great fun with friendly staff, great food and drinks. More

OpenTable Diner -
Cafe Gratitude - San DiegoCafe Gratitude - San Diego
330 reviews
$$$$
Vegetarian / Vegan | Little Italy, San Diego
Booked 32 times today

My second visit and even better than the first! Brought two friends to share the place. The food is outstandingly tasty and fresh. Your Key Lime Pie is the best I've ever tasted - so real. I'll be back. We didn't t take food photos but I can send you a group photo from last time! Thanks to your staff for making it such a wonderful evening again. OOOPS! Let's skip the photo! More

OpenTable Diner -
Ironside Fish & OysterIronside Fish & Oyster
1399 reviews
$$$$
Seafood | Little Italy, San Diego
Booked 75 times today

Loved the amethyst oysters on the half shell (tried one of each available) and the octopus with chorizo! More

OpenTable Diner -
Kettner ExchangeKettner Exchange
566 reviews
$$$$
Contemporary American | Little Italy, San Diego
Booked 52 times today

Had 3 apps and the 40 oz rib eye for 4 ppl which was absolutely amazing...the rib eye not only was delicious but comes on a board with a bunch of different root veggies and onions and artichokes and mushrooms...every bite was a delicious surprise and our waitress (wish I could remember her name but it was MLK nite) was fabulous....super informed..made the dining experience perfect...one of my new fav restaurants in San Diego More

OpenTable Diner -
Bencotto Italian KitchenBencotto Italian Kitchen
1041 reviews
$$$$
Italian | Little Italy, San Diego
Booked 57 times today

Every time we're in little Italy we come here! From date night to birthday's. Great meals, great wine, modern vibe with large windows for people watching. More

OpenTable Diner -
Prepkitchen - Little ItalyPrepkitchen - Little Italy
1012 reviews
$$$$
American | Little Italy, San Diego
Booked 14 times today

I took my nephew and his son to brunch. We had so much fun, and we loved our food. More

OpenTable Diner -
Isola Pizza BarIsola Pizza Bar
137 reviews
$$$$
Italian | Little Italy, San Diego
Booked 4 times today

Happy hour menu was surprising diverse and reasonably priced. Service could have been a bit more attentive,but would highly recommend and return. More

OpenTable Diner -
Juniper & IvyJuniper & Ivy
3095 reviews
$$$$
Contemporary American | Little Italy, San Diego
Booked 121 times today

Amazing experience. Highly recommended for fantastic food in a romantic and enchanting environment. More

OpenTable Diner -
Herb & WoodHerb & Wood
1014 reviews
$$$$
Californian | Little Italy, San Diego
Booked 63 times today

Lively place in Little Italy, San Diego with great food and service. The outside dining patio with fireplaces has nice ambience. More

OpenTable Diner -
MonelloMonello
666 reviews
$$$$
Italian | Little Italy, San Diego
Booked 34 times today

We had a wonderful experience! The risotto on the parmigiana wheel was fantastic! The reason for the 3 star on food, was that the lobster in the lobster pasta was way over cooked, and we never got a check back to address it. Also, the veal dish was underwhelming. More

OpenTable Diner -
Buon AppetitoBuon Appetito
605 reviews
$$$$
Italian | Little Italy, San Diego
Booked 16 times today

Very great food!!! Awesome service!!!! But very loud and hard to have a conversation with a big group of people:( More

OpenTable Diner -
BarbusaBarbusa
526 reviews
$$$$
Italian | Little Italy, San Diego
Booked 39 times today

This was our second time at Barbusa, and it was even better than the first time! All of the servers are friendly and attentive - they really make you feel welcomed. The Fiori de Zucca (fried squash blossoms) are one of my favorite appetizers of all time....definitely a must! My husband loved the Carbonara con Piselli. I ordered the Bolognese al Forno and it was incredible. The portion was huge and I wanted the leftovers, but we were going straight to the theater afterward so I had to leave it behind. All of the Busalacchi restaurants are great, but I think that Barbusa is the best of all! More

OpenTable Diner -
Bar BodegaBar Bodega
2 reviews
$$$$
Tapas / Small Plates | Little Italy, San Diego
Booked 4 times today

Our first time at Bar Bodega was great. The Spanish tapas were excellent as were the number of options. We were there on New Years Eve and they offered a free bottle of sparkling wine and was a nice surprise. We will definitely come back the next time we are in San Diego. More

OpenTable Diner -
Civico 1845Civico 1845
570 reviews
$$$$
Italian | Little Italy, San Diego
Booked 17 times today

My husband and I felt like we were back in Italy the moment we walked in the door of Civico. If you are looking for authentic Italian food and ambience, look no further! Piettro and Dario made us feel right at home, so much that we visited two nights in a row. The architecture and design is regionally inspired using reclaimed wood and draws you in from the street. A must visit in San Diego!! More

OpenTable Diner -
Indigo GrillIndigo Grill
2497 reviews
$$$$
Latin American | Little Italy, San Diego
Booked 20 times today

Beautiful establishment with amazing food and cocktails. I was particularly impressed with the staff and service. I will definitely eat here again. More

OpenTable Diner -
Cloak + PetalCloak + Petal
17 reviews
$$$$
Japanese Speciality | Little Italy, San Diego
Booked 61 times today

We picked Cloak and Pedal to celebrate our engagement. What a great spot we picked! Our server Manaya was knowledgeable and answered every question asked, from liquors to dishes, and everything in between. We could feel the passion she had in describing the menu and the vision Cloak and Pedal wanted their customers to experience. Would go back again and again. More

OpenTable Diner -
Born & RaisedBorn & Raised
267 reviews
$$$$
Steakhouse | Little Italy, San Diego
Booked 92 times today

The decor of the restaurant is beautiful. We had table-side Martinis and they Martinis were excellent. The crab legs, fish, steak were also of excellent quality. My birthday part was a huge success. I would recommend this restaurant as one of the higher end delightful places to pass time with friends and love ones. More

OpenTable Diner -
Davanti Enoteca - Little ItalyDavanti Enoteca - Little Italy
342 reviews
$$$$
Italian | Little Italy, San Diego
Booked 16 times today

It was great food! Quick service and great atmosphere. Would definitely go back. More

OpenTable Diner -
Petrini'sPetrini's
11 reviews
$$$$
Italian | Little Italy, San Diego

Took a date on new year's. Quite place. Lots of choices. Good times More

OpenTable Diner -
Ristorante IllandoRistorante Illando
65 reviews
$$$$
Italian | Little Italy, San Diego
Booked 1 time today

We had a wonderful time celebrating my mother’s birthday. Eddie was an excellent waiter that was very attentive to our needs and also had us rolling in laughter. A must go for anyone looking for an authentic Italian meal in a charming setting. More

OpenTable Diner -
El CaminoEl Camino
85 reviews
$$$$
Mexican | Little Italy, San Diego
Booked 6 times today

Loved El Camino, everything was great except a couple of the servers weren't as pleasant as they should have been. Nothing that can't be worked on! Would definitely recommend More

OpenTable Diner -
NonnaNonna
9 reviews
$$$$
Italian | Little Italy, San Diego
Booked 6 times today

Birthday dinner with a small group. It was wonderful. The noise was a little overwhelming, so we will sit outside next time. Bellisima! More

OpenTable Diner -
Pali Wine Co. - San DiegoPali Wine Co. - San Diego
1 review
$$$$
Tapas / Small Plates | Little Italy, San Diego
Booked 1 time today

It was out first time visiting and we had a great time. Our winetender knew a lot about wines and even gave us extra samples to try. We also had some appetizers which were amazing. I recommend this place to everyone that wants to have a nice quiet evening, have a quick bite and try some wines. More

OpenTable Diner -
Pacific Standard Coastal KitchenPacific Standard Coastal Kitchen
82 reviews
$$$$
Contemporary American | Little Italy, San Diego
Booked 1 time today

the short rib hash and the French toast were delicious! More

OpenTable Diner -
The PassThe Pass
Reviews Coming Soon
$$$$
American | Little Italy, San Diego

A Pop Up located inside 57 Degrees winery which delivers a unique tableside experience where 7 courses are paired with wine and prepared in front of you. We will have a continuously changing menu that will be sent to all reservations prior.
All inclusive pairing of 5 wines with 7 courses for $100 More

Little Italy (San Diego) Diners' Choice Winners

Little Italy (San Diego)'s best restaurants based upon thousands of OpenTable diner reviews
King & Queen Cantina - San DiegoKing & Queen Cantina - San Diego
21 reviews
$$$$
Mexican | Little Italy, San Diego
Booked 10 times today

As always, great fun with friendly staff, great food and drinks. More

OpenTable Diner -
The Kettle RoomThe Kettle Room
27 reviews
$$$$
Contemporary American | Little Italy, San Diego

Love the service and food. Would recommend this place to family and friends. Will be back whenever back inSan Diego. More

OpenTable Diner -
RovinoRovino
115 reviews
$$$$
Italian | Little Italy, San Diego
Booked 3 times today

Great find! We chose Rovino for a birthday celebration. Our experience was outstanding from the moment we arrived. One of the owners seated us and made wonderful suggestions about his favorites from the menu. Everything was delicious--still thinking about the Brussel sprouts appetizer! Very attentive service to make sure we were enjoying our experience. Definitely will be back. More

OpenTable Diner -
Bencotto Italian KitchenBencotto Italian Kitchen
1041 reviews
$$$$
Italian | Little Italy, San Diego
Booked 57 times today

Every time we're in little Italy we come here! From date night to birthday's. Great meals, great wine, modern vibe with large windows for people watching. More

OpenTable Diner -
Kettner ExchangeKettner Exchange
566 reviews
$$$$
Contemporary American | Little Italy, San Diego
Booked 52 times today

Had 3 apps and the 40 oz rib eye for 4 ppl which was absolutely amazing...the rib eye not only was delicious but comes on a board with a bunch of different root veggies and onions and artichokes and mushrooms...every bite was a delicious surprise and our waitress (wish I could remember her name but it was MLK nite) was fabulous....super informed..made the dining experience perfect...one of my new fav restaurants in San Diego More

OpenTable Diner -
Prepkitchen - Little ItalyPrepkitchen - Little Italy
1012 reviews
$$$$
American | Little Italy, San Diego
Booked 14 times today

I took my nephew and his son to brunch. We had so much fun, and we loved our food. More

OpenTable Diner -
Ironside Fish & OysterIronside Fish & Oyster
1399 reviews
$$$$
Seafood | Little Italy, San Diego
Booked 75 times today

Loved the amethyst oysters on the half shell (tried one of each available) and the octopus with chorizo! More

OpenTable Diner -
Cafe Gratitude - San DiegoCafe Gratitude - San Diego
330 reviews
$$$$
Vegetarian / Vegan | Little Italy, San Diego
Booked 32 times today

My second visit and even better than the first! Brought two friends to share the place. The food is outstandingly tasty and fresh. Your Key Lime Pie is the best I've ever tasted - so real. I'll be back. We didn't t take food photos but I can send you a group photo from last time! Thanks to your staff for making it such a wonderful evening again. OOOPS! Let's skip the photo! More

OpenTable Diner -
Buon AppetitoBuon Appetito
605 reviews
$$$$
Italian | Little Italy, San Diego
Booked 16 times today

Very great food!!! Awesome service!!!! But very loud and hard to have a conversation with a big group of people:( More

OpenTable Diner -
Herb & WoodHerb & Wood
1014 reviews
$$$$
Californian | Little Italy, San Diego
Booked 63 times today

Lively place in Little Italy, San Diego with great food and service. The outside dining patio with fireplaces has nice ambience. More

OpenTable Diner -