Best American Restaurants in Houston Medical Center

Tinys No.5Tinys No.5
(116)
$$$$
American | W. University / Med Center, Houston
Tiny BoxwoodsTiny Boxwoods
(244)
$$$$
American | River Oaks, Houston
Lucio's BYOB & GrillLucio's BYOB & Grill
(506)
$$$$
American | Midtown / Montrose, Houston
Killen's STQKillen's STQ
(461)
$$$$
American | West Side, Houston
The RemingtonThe Remington
(103)
$$$$
American | Galleria / Uptown, Houston
The PassThe Pass
(578)
$$$$
American | Midtown / Montrose, Houston
ProvisionsProvisions
(1023)
$$$$
American | Midtown / Montrose, Houston
Riel RestaurantRiel Restaurant
(246)
$$$$
American | Midtown / Montrose, Houston
Just DinnerJust Dinner
(619)
$$$$
American | Midtown / Montrose, Houston
Pax AmericanaPax Americana
(615)
$$$$
American | Midtown / Montrose, Houston
Ruggles Black RestaurantRuggles Black Restaurant
(229)
$$$$
American | Upper Kirby / Shepherd Corridor, Houston
The Federal GrillThe Federal Grill
(770)
$$$$
American | Heights / Washington, Houston
Rainbow LodgeRainbow Lodge
(2371)
$$$$
American | Heights / Washington, Houston
Bistro MenilBistro Menil
(198)
$$$$
American | Midtown / Montrose, Houston

Best Italian Restaurants in Houston Medical Center

Antica OsteriaAntica Osteria
(664)
$$$$
Italian | W. University / Med Center, Houston
Da MarcoDa Marco
(775)
$$$$
Italian | Midtown / Montrose, Houston
Arturo Boada CuisineArturo Boada Cuisine
(151)
$$$$
Italian | Galleria / Uptown, Houston
Damian's Cucina ItalianaDamian's Cucina Italiana
(1828)
$$$$
Italian | Midtown / Montrose, Houston
Vinoteca PoscolVinoteca Poscol
(127)
$$$$
Italian | Midtown / Montrose, Houston
Sorrento Ristorante ItalianoSorrento Ristorante Italiano
(1787)
$$$$
Italian | Midtown / Montrose, Houston
Amalfi Ristorante Italiano & BarAmalfi Ristorante Italiano & Bar
(230)
$$$$
Italian | Galleria / Uptown, Houston
North Italia – BLVDNorth Italia – BLVD
(1446)
$$$$
Italian | Galleria / Uptown, Houston
La Griglia - HoustonLa Griglia - Houston
(1185)
$$$$
Italian | River Oaks, Houston
Divino Italian RestaurantDivino Italian Restaurant
(296)
$$$$
Italian | River Oaks, Houston
PotentePotente
(159)
$$$$
Italian | Downtown, Houston
Mia Bella - Greenway PlazaMia Bella - Greenway Plaza
(89)
$$$$
Italian | Upper Kirby / Shepherd Corridor, Houston
Grotto - HoustonGrotto - Houston
(899)
$$$$
Italian | Galleria / Uptown, Houston
Sud Italia RistoranteSud Italia Ristorante
(352)
$$$$
Italian | Rice Village, Houston
Mezzanotte RistoranteMezzanotte Ristorante
(565)
$$$$
Italian | Cypress, Houston

Popular restaurants in Houston

Browse some of the most booked restaurants in Houston

Mastro's Steakhouse - Houston
(578)
$$$$
Steakhouse | Galleria / Uptown
Willie G's
(97)
$$$$
Seafood | Galleria / Uptown
View all Houston restaurants

Treat your taste buds: Explore Houston Medical Center restaurants.

Houston Medical Center Restaurants

Tinys No.5Tinys No.5
116 reviews
$$$$
American | W. University / Med Center, Houston

Excellent service. Loved the cheese plate and the bison. Always have a new a good beer on tap. More

OpenTable Diner -
Antica OsteriaAntica Osteria
664 reviews
$$$$
Italian | W. University / Med Center, Houston

The food is excellent. The service is great. One of our favorite places. More

OpenTable Diner -
Lucille'sLucille's
1331 reviews
$$$$
Comfort Food | W. University / Med Center, Houston

Always love fried green tomatoes and shrimp and grits! Loved my cocktail too! More

OpenTable Diner -
El MesonEl Meson
472 reviews
$$$$
Spanish | W. University / Med Center, Houston

Great service, and they don't rush you through your meal. Food is wonderfully prepared with a mix of Spanish, Cuban, and Mexican dishes. More

OpenTable Diner -
Third CoastThird Coast
72 reviews
$$$$
Contemporary American | W. University / Med Center, Houston

My wife and I went for Valentines day. Philip, the GM, was attentive and gracious. The service was top notch. More

OpenTable Diner -
Paladora Lounge - Houston Marriott Medical Center/Museum DistrictPaladora Lounge - Houston Marriott Medical Center/Museum District
1 review
$$$$
American | W. University / Med Center, Houston

So easy. Everyone was attentive. Food was surprisingly good. More

OpenTable Diner -
Mi LunaMi Luna
149 reviews
$$$$
Tapas / Small Plates | W. University / Med Center, Houston

Didn't realy need it a reservation. Food is bit expensive, but well worth it... More

OpenTable Diner -
Driscoll'sDriscoll's
1 review
$$$$
American | W. University / Med Center, Houston

One of few restaurants open on Christmas day. Nice ambiance, friendly service. Got a couple orders wrong, but quickly resolved. Thankful for this option when everything else seemed closed. More

OpenTable Diner -
Eclair ParisEclair Paris
Reviews Coming Soon
$$$$
French | W. University / Med Center, Houston

As a native Parisian with over 30 successful years of restaurant leadership in France, Martial Demonet is ready to share his culinary expertise with the Houston community the introduction of Eclair, a French bistro and patisserie.More

Houston Medical Center Diners' Choice Winners

Houston Medical Center's best restaurants based upon thousands of OpenTable diner reviews
Tinys No.5Tinys No.5
116 reviews
$$$$
American | W. University / Med Center, Houston

Excellent service. Loved the cheese plate and the bison. Always have a new a good beer on tap. More

OpenTable Diner -
El MesonEl Meson
472 reviews
$$$$
Spanish | W. University / Med Center, Houston

Great service, and they don't rush you through your meal. Food is wonderfully prepared with a mix of Spanish, Cuban, and Mexican dishes. More

OpenTable Diner -
Lucille'sLucille's
1331 reviews
$$$$
Comfort Food | W. University / Med Center, Houston

Always love fried green tomatoes and shrimp and grits! Loved my cocktail too! More

OpenTable Diner -
Monarch @ Hotel ZazaMonarch @ Hotel Zaza
672 reviews
$$$$
Contemporary American | W. University / Med Center, Houston

Mother-daughter luncheon More

OpenTable Diner -
Antica OsteriaAntica Osteria
664 reviews
$$$$
Italian | W. University / Med Center, Houston

The food is excellent. The service is great. One of our favorite places. More

OpenTable Diner -
Third CoastThird Coast
72 reviews
$$$$
Contemporary American | W. University / Med Center, Houston

My wife and I went for Valentines day. Philip, the GM, was attentive and gracious. The service was top notch. More

OpenTable Diner -
Mi LunaMi Luna
149 reviews
$$$$
Tapas / Small Plates | W. University / Med Center, Houston

Didn't realy need it a reservation. Food is bit expensive, but well worth it... More

OpenTable Diner -

Discover W. University / Med Center

Everything's bigger in Texas, and that includes the food scene. Cuisine in the W. University/Med Center area of town has everything from chain eateries to privately owned restaurants. Pique your desire for Thai with diners near Houston's notable museums. There is also the option of enjoying a bit of Italian takeout with several pizza eateries scattered throughout. You can't leave the W. University/Med Center region without trying some of Houston's famous barbecue. Wings and waffles are also a big deal in these parts of town. Want local favorites? You can stop by any American cuisine restaurant that's big on comfort foods to get a taste of the city.