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Best American Restaurants in W. University / Med Center


141 restaurants available nearby

A photo of Clark's Oyster Bar - Houston restaurant
Price: Expensive
• American • Southeast Houston
Booked 79 times today
Located in a former auto shop in the vibrant Montrose neighborhood near The Menil Collection and Museum District, Clark’s Houston is the third and largest location of our popular neighborhood oyster bar and seafood restaurant. Opened in Fall 2023, Clark’s features freshly shucked oysters, crudo, lobster roll, daily fish specials, caviar and blini, bowls of chowder and cioppino as well as a much-loved burger and shoestring fries.The restaurant specializes in martinis and signature cocktails as well as an extensive Champagne and wine list. The design is light, bright, and airy with nautically-themed touches including a centerpiece fish tank, teak wood furniture, bright white walls, and blue and turquoise tones.In addition to a marble-topped oyster bar and dining room, there’s a large, covered patio for prime people watching and oyster slurping. Clark’s Houston also offers a semi-private dining room for special occasions and events.
A photo of Hudson House - River Oaks restaurant
Price: Moderate
• American • River Oaks
Booked 75 times today
With its East Coast-inspired “old-school casual” design and menu, Hudson House offers straightforward, timeless American dishes for lunch and dinner. Oysters are flown in daily and are best paired with their legendary “World’s Coldest Martinis."
A photo of Eunice restaurant
Price: Moderate
• American • Upper Kirby / Shepherd Corridor
Booked 26 times today
Eunice is a standout establishment that masterfully delivers Creole/Cajun/Southern cuisine. As the reviews indicate, their sophisticated take on regional dishes has won over patrons who praise the freshness of ingredients and innovative versions of classic recipes. The restaurant boasts a range of dishes including Gulf Fish, Shrimp & Grits, and Crawfish Etouffee, which are notable for their intricate flavors and modern presentation. The restaurant's attention to detail extends to its feature of a Raw Bar, daily-changing 'Power Lunch' options, and a selection of desserts like Wild Berry Cobbler and Chocolate Cake. The excellence of Eunice's food is further accentuated by the attentive and professional service, creating an overall dining experience that is consistently deemed "perfect", "world-class", and "amazing". This, along with the elegant ambiance, makes Eunice a beloved destination for an authentic and refined Creole/Cajun culinary journey.
A photo of Grace's restaurant
Price: Expensive
• American • Upper Kirby / Shepherd Corridor
Booked 37 times today
Grace's is widely hailed for its mastery of American cuisine, specifically its offering of classic Southern-style dishes. Many patrons have expressed their admiration for Grace's ability to not only serve great food but also elevate iconic staples of American cuisine. Highlights from their menu include the "Maw Maw’s pot roast", the "chicken fried pork chop", and the "creole chicken stuffed with crab meat". One reviewer declared their fried chicken to be the best they've had. Others have praised their seafood offerings, stating that their "crab and shrimp campenchana" surpasses the versions from other popular seafood joints. Repeated visits and the intention to become regulars suggest that Grace's is indeed a gem in the restaurant scene. The consistent praises for their excellent service, relaxed atmosphere, and superb food make Grace's a must-visit for lovers of American cuisine.
A photo of Lucille's restaurant
Price: Expensive
• American • Museum District
Booked 51 times today
Lucille's restaurant has received high acclaim for its exceptional comfort food. The delightful reviews speak volumes about the quality of food and service offered. Patrons consistently rave about the unique twist on Southern comfort dishes, including the popular hot rolls with chili, oxtail omelette, collard greens, and truffle mac and cheese. The food at Lucille's is described as flavorful and deliciously indulgent, making it some of the best comfort food that patrons have ever had. The warm, friendly service and cozy ambiance, reminiscent of a bygone Southern home, only add to the charm of this neighborhood gem. Whether it's for a special event or a casual meal, Lucille's always appears to be a recommended choice for a satisfying comfort food experience.
A photo of Liberty Kitchen & Oysterette - River Oaks restaurant
Price: Expensive
• American • River Oaks
Booked 31 times today
Liberty Kitchen & Oysterette - River Oaks, located in Houston, Texas, has earned itself the reputation of being among the best seafood restaurants in the area. The consistent quality and freshness of the seafood from their menu are highlighted in many customer reviews, and dishes such as the charbroiled oysters, raw oysters, and seafood gumbo have been particularly praised. In addition to their culinary expertise, their exceptional service has also been greatly appreciated by patrons. As one customer said, "The food and service were incredible. The seafood was extremely fresh. It was one of the best dining experiences we have had in a long time." The restaurant's friendly staff, devotion to high-quality seafood and overall enjoyable dining experience make it an unmissable destination for seafood lovers in Houston.
A photo of Relish Restaurant and Bar restaurant
Price: Moderate
• American • River Oaks
Booked 30 times today
Relish Restaurant and Bar, located in the heart of Houston, is a jewel in the crown of Contemporary American cuisine. Many guests commend it for its use of fresh, quality ingredients and innovative approach to traditional dishes, without ever seeming overly elaborate. The "Good ole American fried chicken and greens" and the "deviled eggs" have been particularly praised for their rich flavors and textures. One can expect an extraordinary dining experience with top-notch service, as the staff are noted for their attentiveness and ability to personalize suggestions. The ambiance is upscale but relaxed, making it an excellent choice for fine dining. With consistent quality, this restaurant has earned its place in many of patrons' "Top Ten" lists. For those who appreciate wonderful food, smooth cocktails, and warm conversations, Relish Restaurant and Bar is a must-visit.
A photo of The Annie Café & Bar restaurant
Price: Expensive
• American • Galleria / Uptown
Booked 24 times today
The Annie Café & Bar offers a fresh take on Texas-influenced American cuisine by award-winning Executive Chef Robert Del Grande. A concept from Houston-based Berg Hospitality Group and restaurateur Benjamin Berg, the revamped legendary restaurant provides Houstonians with a well-rounded, approachable menu in a vibrant, sophisticated atmosphere. We are open daily for lunch, dinner, happy hour and weekend brunch! We are also offering online ordering for curbside take-out and delivery at this link: https://www.theanniehouston.com/order-pickup#getting-started?location=houston
A photo of Willie G's restaurant
Price: Moderate
• American • Galleria / Uptown
Booked 34 times today
Willie G's is widely recognized as a high-quality seafood restaurant due to numerous rave reviews from customers. Patrons praise not only the tantalizing variety of seafood dishes, such as the Rockefeller Oysters, Tempura Shrimp, Seafood Platter, and Seafood Salad Trio, but also the exceptional seasoning and freshness of the food. The restaurant is celebrated for its impressive seafood selection, excellent ambiance, and attentive service, with the staff often receiving shout-outs for their patience and professionalism. Many patrons become repeat customers, bringing friends and out-of-town guests, and even choosing Willie G's for special occasions. As one delighted customer affirms, "Willie G's is never a disappointment. Food is great. Restaurant has great ambiance". And for many, it is "the Best Seafood Restaurant in Houston."
A photo of Ruggles Black -West Alabama restaurant
Price: Expensive
• American • Upper Kirby / Shepherd Corridor
Booked 18 times today
Ruggles Black - West Alabama is a purveyor of exceptional American cuisine in Houston, which its patrons consistently praise for offering an extensive and delectable menu. Reviewers commend the restaurant's ability to cater to those following a Keto diet, with many dubbing it a "great date night venue." The dishes, such as the grilled Brussel sprouts, chicken wings, and pecan-crusted snapper, receive accolades for their freshness and flavor. The ambiance and decor are also noted for contributing to the restaurant's warm atmosphere, with one reviewer stating, "All the food we have tried is absolutely phenomenal! We also love the decor and ambiance of the restaurant." Despite the potential for high noise levels due to crowdedness, Ruggles Black continues to be a favorite for couples and friends alike.
‘About the restaurant’ descriptions have been generated using an artificial intelligence model comprised of OpenTable proprietary data that has not been independently verified by OpenTable. The content is presented as-is, for informational purposes only.
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