Skip to Main Content
OpenTable logo
  1. Home
  2. United States
  3. San Diego

La Mesa Restaurants

Make a free reservation

Quick Search:
All 3757 restaurants in San Diego

Get it delivered

View all

Outdoor dining

View all

Available for lunch now

View all

Order takeout

View all

Italian delivery

View all

Wine tasting

View all

Experiences trending in San Diego

View all

Treat your taste buds: Explore La Mesa restaurants

La Mesa Diners' Choice Winners

La Mesa's best restaurants based upon thousands of OpenTable diner reviews

La Mesa's best restaurants based upon thousands of OpenTable diner reviews

A photo of Brigantine La Mesa restaurant
4.7
Exceptional(2784)
$$$$
• Seafood • La Mesa
Booked 62 times today

A San Diego tradition since 1969, the Brigantine has received many accolades in our 40+ year history: "BEST SEAFOOD", "BEST CASUAL SEAFOOD", "BEST HAPPY HOUR", and even "BEST SWORDFISH IN THE WORLD", according to USA Today - just to name a few.Well-known for our signature Clam Chowder, Grilled...

A photo of Antica Trattoria restaurant
4.7
Exceptional(1501)
$$$$
• Contemporary Italian • La Mesa
Booked 19 times today

Antica Trattoria is a warm restaurant with an old-fashioned sense of hospitality that quickly became a gathering place for dinners in Lake Murray and the rest of San Diego when it opened in 2001. For Executive Chef and Owner Francesco Basile, good cuisine is about honest flavors, fresh ingredients...

A photo of BO-beau kitchen + garden restaurant
4.6
Exceptional(1419)
$$$$
• Contemporary French / American • La Mesa
Booked 13 times today

BO beau kitchen + garden is located in the Village of La Mesa. BO beau offers Sophisticated Comfort Food with Global Inspirations. We have 24 Beers on tap, a worldly wine list and a full bar with eclectic cocktails.

A photo of Oyster & Pearl Bar Restaurant restaurant
4.4
Awesome(65)
$$$$
• American • La Mesa
Booked 8 times today

Our mission at Oyster & Pearl is to serve delicious food made with seasonal, all-natural, organic, locally-sourced, and sustainably-produced ingredients whenever possible. We believe this approach provides the most healthful and flavorful cuisine while promoting an awareness of the role independent...

A photo of Farmer's Table - La Mesa restaurant
4.2
Awesome(1349)
$$$$
• Farm-to-table • La Mesa
Booked 43 times today

Excited to announce that we officially have four locations open in San Diego including Bay Park, Little Italy, La Mesa, and Chula Vista. As a family run operation we believe every good neighborhood deserves an eatery where locals and visitors can enjoy “honest food done right”. Here at Farmers...

Discover La Mesa

When eating in Southern California, the seafood is, of course, the star. The Greater San Diego area, including La Mesa, houses some of the best seafood restaurants in the country. Their easy access to Pacific bounty, like tuna, salmon, calamari, and shellfish, means some of the freshest ingredients are in the hands of some of the most experienced seafood chefs in the business. This quality of fish also means there is a lot of great sushi. There is a growing farm-to-table movement in this area, driven by access to many local produce vendors. Without a doubt, a strong Latin influence exists on East County's cuisine. The area has everything from fantastic taco joints to high-end traditional fare, all worth checking out.

When eating in Southern California, the seafood is, of course, the star. The Greater San Diego area, including La Mesa, houses some of the best seafood restaurants in the country. Their easy access to Pacific bounty, like tuna, salmon, calamari, and shellfish, means some of the freshest ingredients are in the hands of some of the most experienced seafood chefs in the business. This quality of fish also means there is a lot of great sushi. There is a growing farm-to-table movement in this area, driven by access to many local produce vendors. Without a doubt, a strong Latin influence exists on East County's cuisine. The area has everything from fantastic taco joints to high-end traditional fare, all worth checking out.

Your Local Dining Scene

  • AAA OpenTable Gifts
    OpenTable Gifts gift cards for restaurants!
  • Metropolitan Washington Restaurant Week
    Metropolitan Washington Restaurant Week
  • 1K Days - General
    Earn Free Meals Faster - 1,000-Point Tables
  • New Restaurants Start Page - San Diego
    Find Hot New Restaurants Near You!
  • OpenTable Mobile - San Diego Restaurants on the go!
    OpenTable Mobile: Free Apps For Your Phone!
  • Business Bites - San Diego Participating Restaurants
    Business Bites - Weekday Lunches
  • Gluten Free Dining - San Diego Participating Restaurants
    Gluten-Free Dining - Restaurants & Menus
  • Great for Groups - San Diego Restaurants
    Group Dining - Tables for 8 to 20
  • Outdoor Dining - San Diego Participating Restaurants
    Outdoor Dining - Al Fresco Dining
  • Sunday Brunch - San Diego Restaurants
    Sunday Brunch - Restaurants & Menus
  • DiRoNA - Restaurant Awards
    DiRoNA Winners - Dine Where the Chefs Dine
  • Vegan / Vegetarian Dining - San Diego Restaurants
    Vegan & Vegetarian Friendly Dining Options
  • Artisanal Cocktails - San Diego Restaurants
    Artisanal Cocktails - Lists with a Twist
  • Free Corkage & BYOB - San Diego Restaurants
    Free Corkage & BYOB - Bring Your Own Drink
  • Theater Menus - San Diego Participating Restaurants
    Theatre Menus - Book Pre & Post-Show Tables

Explore OpenTable

Become an Insider

Gain access to exclusive offers, best-of lists, local events & more (you can unsubscribe any time).

  • Privacy Policy
  • Terms of Use
  • Cookies and Interest-Based Ads
  • Do Not Sell My Info (California)
Copyright © 2021 OpenTable, Inc. 1 Montgomery St Ste 700, San Francisco CA 94104 - All rights reserved.
OpenTable is part of Booking Holdings, the world leader in online travel and related services.
Booking LogoPriceline LogoKAYAK LogoAgoda LogoRentalcars LogoOpenTable Logo