Enable JavaScript to run this app.
Skip to main content
OpenTable logo
  1. Home
  2. United States
  3. San Diego

Best Contemporary American Restaurants in La Mesa

Price
Regions
Neighborhoods
Top Rated
Dining Options
Seating Options
Award-winning
Accessibility

31 restaurants available nearby

How are Featured results ranked

A photo of KnB Bistro - College Area restaurant
4.7
Exceptional(1)
Price: Moderate
• Contemporary american • College Area
Delicious Food, Strong Spirits, And Bubbling Brews All In One Unique Experience.BISTRO | BAR | BOTTLE SHOP | BREWERY | BANQUET ROOM | 32 BEERS ON TAP | IN-HOUSE TASTINGSWe are a bottle shop, brewery, bistro, and bar. Our selection is MASSIVE and there's nothing we can't do
A photo of Starlite restaurant
4.7
Exceptional(290)
Price: Expensive
• Contemporary american • Mission Hills
Booked 117 times today
Starlite: A timeless San Diego icon with a fresh future, helmed by Chef Ted Smith.Please note: Our establishment is 21+
A photo of Quixote restaurant
4.7
Exceptional(1237)
Price: Moderate
• Contemporary american • North Park
Booked 63 times today
Quixote in North Park, San Diego is a culinary gem that beautifully captures the essence of American cuisine with a delightful twist. Known for its "amazing food" and "incredible service," Quixote offers a menu filled with creative and exciting dishes that push the boundaries of traditional American flavors. Diners rave about the "best guacamole ever" and the must-try "crab corn donut," highlighting the restaurant's innovative approach. The "impeccable ambiance" and "warm atmosphere" create a memorable dining experience, perfect for any occasion. Quixote's dedication to quality and authenticity makes it a standout choice for anyone seeking a unique American dining adventure.
A photo of Sessions by the Bay restaurant
4.6
Exceptional(181)
Price: Moderate
• Contemporary american • National City
Booked 53 times today
Welcome to Sessions By The Bay — San Diego’s first and only 21+ cannabis consumption lounge and dispensary, located right on the waterfront in National City.More than just a weed dispensary, we offer a one-of-a-kind space where premium cannabis, dining, live music, and cutting-edge immersive art spaces come together to create an unforgettable experience.Lounge reservations are highly encouraged; walk-ins welcome based on availability.Lounge Access Details:• Monday – Thursday: FREE lounge entry for all San Diego county locals with valid ID.• Lounge Entry Fee: $10 for non-locals or non-qualifying visitors.*Lounge fee is also waived with a $75 subtotal purchase in the dispensary for anyone. Must show same day receipt.We recommend arriving 30 minutes early to complete your dispensary purchase for lounge use.Guests may bring approved electronic devices for a $10 corkage fee. Standard vape batteries are exempt. Cancel 24+ hours for refund. For help, please call us (619) 935-7374
A photo of Brisa restaurant
4.2
Awesome(56)
Price: Moderate
• Contemporary american • Little Italy
Booked 27 times today
Brisa is a lively spot in San Diego’s Little Italy serving up bold Latin and Asian fusion flavors in a fun, laid-back setting. The menu is all about fresh ingredients and creative twists—from zesty ceviches to spicy noodles and shareable street food-inspired plates. With its vibrant, plant-filled space and upbeat vibe, Brisa is the perfect hangout for casual bites, craft cocktails, and good times with friends.
A photo of Books + Records restaurant
4.7
Exceptional(488)
Price: Expensive
• Contemporary american • Banker's Hill
Booked 16 times today
Books + Records in Banker's Hill, San Diego, is a standout Cocktail Bar, celebrated for its "inventive and creative drinks." Patrons rave about the "perfectly executed" cocktails, including unique infusions like the grey tea drink, described as "delish!" This cocktail haven consistently makes Eater's list of San Diego's Hottest Cocktail Bars, showcasing the mixology mastery of its skilled bartenders. The ambiance is lively, featuring live music that complements the vibrant atmosphere. With "attentive and friendly" service and a menu that pairs perfectly with their drinks, Books + Records offers an unmatched cocktail experience that invites you to savor every sip.
A photo of STK- San Diego restaurant
4.3
Awesome(3533)
Price: Expensive
• Contemporary american • Downtown
Booked 34 times today
STK- San Diego stands out as a premier destination for authentic American cuisine, perfectly blending traditional steakhouse excellence with a vibrant, modern twist. Located in the heart of Downtown San Diego, this steakhouse offers a "high-energy dining experience" that captivates patrons from start to finish. Guests rave about the "spectacular food" and "exceptional service," making it a top choice for special occasions and casual outings alike. The menu, featuring mouth-watering steaks and reimagined American classics, showcases the highest quality ingredients with traceable sourcing. Whether celebrating a milestone or enjoying a lively Happy Hour, STK promises an unforgettable American dining adventure.
A photo of ARLO San Diego restaurant
4.4
Awesome(843)
Price: Moderate
• Contemporary american • Mission Valley
Booked 14 times today
ARLO San Diego in Mission Valley is a seafood lover's paradise, offering an authentic and exquisite dining experience. With dishes crafted from fresh, local ingredients, ARLO stands out as a beacon of quality Seafood cuisine. Diners rave about the "tender and packed with flavor" octopus and the "perfectly cooked and seasoned" Pan Roasted Seabass, praising the melt-in-your-mouth quality of the seafood. The restaurant's vibrant atmosphere, coupled with a sweeping patio and inventive cocktails, makes it a must-visit destination. ARLO's accolades, including Best Hotel Restaurant in San Diego Magazine's Best of 2024, further attest to its exceptional seafood offerings.
A photo of Parc Bistro-Brasserie restaurant
4.8
Exceptional(3292)
Price: Moderate
• Contemporary american • Banker's Hill
Booked 39 times today
Parc Bistro-Brasserie, nestled in the vibrant neighborhood of Banker's Hill in San Diego, is a hidden gem that has earned its place among OpenTable's "100 Best Neighborhood Gems in America for 2021." This charming bistro not only excels in French cuisine but also offers a delightful blend of American flavors, making it a standout choice for those seeking authentic American fare. Diners rave about the "amazing experience" and "excellent food and great service" that make every visit memorable. With a cozy ambiance and a menu that promises both tradition and innovation, Parc Bistro-Brasserie is a must-visit for anyone craving American culinary excellence.
A photo of LIPS - San Diego restaurant
4.9
Exceptional(154)
Price: Expensive
• Contemporary american • North Park
Booked 9 times today
Lips has been San Diego's ULTIMATE in Drag Dining for 25 years! Dinner, Drinks & fabulous Drag Shows, as well as Brunch on Saturdays & Sundays. Enjoy a great meal & cocktails served up by over-the-top Drag Queens. DIFFERENT SHOWS WEDNESDAY THRU SUNDAY. Wed: Bithcy Bingo; Thur: Dining with the Divas; Fri: Glitz & Glam Dinner; Sat: 2 Dragalicious Brunches & 2 Glitz & Glam Dinners; Sun: 2 Gospel Brunches & Sunday Nite Showstoppers. ***Prices- Wed/Thur/Sun Dinner: $35.95(shoe & 3-course dinner, drinks additional); Sat/Sun Brunch: $42.95(Show, meal & bottomless Mimosas/Champagne/Bloody Mary; Fri/Sat Nite: $49.95(show & 3-course dinner,drinks additional) All shows subject to 7.75%sales tax & 20% suggested gratuity; $12 celebration package for Birthdays/Bachelorette/Anniversary/Promotion/Graduation. 16+ to enter; 21+ to Drink. GOVERNMENT ID REQUIRED-ALL IDS CHECKED AT THE DOOR

How is content generated

See what locals rave about

From verified diners like you
From verified diners like you

Discover best Contemporary American restaurants in La Mesa

Discover the vibrant dining scene in La Mesa, East County San Diego, where contemporary American cuisine takes center stage. This area is a culinary hotspot, offering a diverse range of restaurants that specialize in modern American dishes, blending traditional flavors with innovative twists. Each establishment boasts a unique ambiance, from cozy, intimate settings to lively, upscale environments, catering to a variety of dining preferences. The menus are thoughtfully curated, featuring locally-sourced ingredients and seasonal specialties that highlight the region's abundant produce and artisanal products. Patrons can expect exceptional service and a memorable dining experience, underscored by a commitment to quality and creativity. As a cultural hub in San Diego, La Mesa's contemporary American restaurants not only satisfy the palate but also reflect the area's dynamic gastronomic excellence. Whether you're a local foodie or a visitor, the contemporary American eateries in La Mesa promise an enriching culinary journey.

OpenTable
  • About Us
  • Blog
  • Careers
  • Press
More
Businesses
  • Restaurant Management Solutions
  • Restaurant Reservation Software
  • Restaurant Marketing Software
  • Restaurant Event Software
  • OpenTable For Restaurants
  • OpenTable For Restaurant Groups
  • Restaurant Resources
  • OpenTable Pricing & Plans
Join us on
  • Privacy Policy
  • Terms of Use
  • Cookies and Interest-Based Ads
  • Do Not Sell or Share My Personal Information
  • Cookie Preferences
Copyright © 2025 OpenTable, Inc. 1 Montgomery St Ste 500, San Francisco CA 94104 - All rights reserved.
OpenTable is part of Booking Holdings, the world leader in online travel and related services.
Booking Logo
Priceline Logo
KAYAK Logo
Agoda Logo
OpenTable Logo