Best American Restaurants in Uptown Denver

Jack's Uptown GrilleJack's Uptown Grille
(39)
$$$$
American | Uptown, Denver
Booked 2 times today
Randolph's at Warwick Denver HotelRandolph's at Warwick Denver Hotel
(661)
$$$$
American | Uptown, Denver
Booked 7 times today
the plimoththe plimoth
(876)
$$$$
American | Central, Denver
Booked 13 times today
Williams & GrahamWilliams & Graham
(22)
$$$$
American | Highlands, Denver
Booked 2 times today
Root DownRoot Down
(5371)
$$$$
American | Highlands, Denver
Booked 76 times today
Kevin Taylor's At The Opera HouseKevin Taylor's At The Opera House
(937)
$$$$
American | Downtown / LoDo, Denver
Citizen RailCitizen Rail
(108)
$$$$
American | Downtown / LoDo, Denver
Booked 47 times today
12@MADISON12@MADISON
(189)
$$$$
American | Downtown / LoDo, Denver
Booked 24 times today
Satchel's on 6thSatchel's on 6th
(658)
$$$$
American | Cherry Creek, Denver
Booked 12 times today
Table 6Table 6
(1624)
$$$$
American | Cherry Creek, Denver
Booked 33 times today
Butcher's BistroButcher's Bistro
(199)
$$$$
Steak | River North (Denver), Denver
Booked 4 times today
AssignmentsAssignments
(331)
$$$$
American | Central, Denver
Bremen's Wine & TapBremen's Wine & Tap
(17)
$$$$
American | Highlands, Denver
Booked 8 times today
Corridor 44Corridor 44
(425)
$$$$
American | Downtown / LoDo, Denver
Booked 6 times today
Hearth & DramHearth & Dram
(189)
$$$$
American | Downtown / LoDo, Denver
Booked 8 times today

Best Italian Restaurants in Uptown Denver

CopertaCoperta
(430)
$$$$
Italian | Uptown, Denver
Booked 27 times today
Brik on YorkBrik on York
(31)
$$$$
Italian | Uptown, Denver
Booked 4 times today
Tony P's Bar & Pizzeria - UptownTony P's Bar & Pizzeria - Uptown
(51)
$$$$
Italian | Uptown, Denver
Booked 2 times today
North Italia – DenverNorth Italia – Denver
(1789)
$$$$
Italian | Cherry Creek, Denver
Booked 44 times today
Barolo GrillBarolo Grill
(2269)
$$$$
Italian | Cherry Creek, Denver
Booked 30 times today
SpuntinoSpuntino
(306)
$$$$
Italian | Highlands, Denver
Booked 10 times today
Piatti - DenverPiatti - Denver
(1845)
$$$$
Italian | Cherry Creek, Denver
Booked 26 times today
Il PostoIl Posto
(222)
$$$$
Italian | River North (Denver), Denver
Booked 22 times today
CUCINA Colore of Cherry CreekCUCINA Colore of Cherry Creek
(1143)
$$$$
Italian | Cherry Creek, Denver
Booked 14 times today
Osteria MarcoOsteria Marco
(4091)
$$$$
Italian | Downtown / LoDo, Denver
Booked 62 times today
Quality Italian- DenverQuality Italian- Denver
(362)
$$$$
Italian | Cherry Creek, Denver
Booked 69 times today
Ristorante Lo StellaRistorante Lo Stella
(455)
$$$$
Italian | Downtown / LoDo, Denver
Booked 3 times today
Firenze a TavolaFirenze a Tavola
(1062)
$$$$
Italian | Highlands, Denver
Booked 5 times today
Odyssey Italian Restaurant & Wine BarOdyssey Italian Restaurant & Wine Bar
(863)
$$$$
Italian | Central, Denver
Booked 16 times today
Bar DoughBar Dough
(374)
$$$$
Italian | Highlands, Denver
Booked 48 times today
LucaLuca
(1662)
$$$$
Italian | Central, Denver
Booked 16 times today
Carmine's On PennCarmine's On Penn
(1695)
$$$$
Italian | Wash Park, Denver
Booked 12 times today
PanzanoPanzano
(4315)
$$$$
Italian | Downtown / LoDo, Denver
Booked 61 times today

Popular restaurants in Denver

Browse some of the most booked restaurants in Denver

Izakaya Den
(377)
$$$$
Japanese | Wash Park
El Five
(742)
$$$$
Mediterranean | Highlands
Quality Italian- Denver
(625)
$$$$
Italian | Cherry Creek
True Food Kitchen - Denver
(659)
$$$$
Mediterranean | Cherry Creek
View all Denver restaurants

Treat your taste buds: Explore Uptown Denver restaurants.

Uptown Denver Restaurants

Patxi's Pizza UptownPatxi's Pizza Uptown
26 reviews
$$$$
Pizzeria | Uptown, Denver
Booked 1 time today

The server was great as was the food. A little noisy but it is a pizza joint. More

OpenTable Diner -
Atelier by RadexAtelier by Radex
174 reviews
$$$$
French | Uptown, Denver
Booked 5 times today

I have always loved Radek Cerny's food. His seafood is outstanding and his sauces are perfection. The menu has lots of options for everyone. I especially love Atelier at lunch when the sun pours into the beautiful dining room. More

OpenTable Diner -
Bastien's RestaurantBastien's Restaurant
307 reviews
$$$$
Steakhouse | Uptown, Denver
Booked 1 time today

Food and atmosphere was great, I will return and it was very relaxing to listen to Frank Sinatra, the service could have been a lot better if the waitress was not rushing us to order. She was very rude and kept coming back to see if we were ready to order. We had an early reservstion just so we could take our time, and there was no need for the rush because there were very few people in the restaurant. More

OpenTable Diner -
Solera Restaurant & Wine BarSolera Restaurant & Wine Bar
1655 reviews
$$$$
Contemporary American | Uptown, Denver
Booked 5 times today

Solera has thoughtful, well-executed menu with excellent service. More

OpenTable Diner -
Beast and BottleBeast and Bottle
1031 reviews
$$$$
Contemporary American | Uptown, Denver
Booked 32 times today

Great interesting brunch options. Kids meals were lacking, and breakfast doesn’t include toast. However, all the food was great and the service was excellent. More

OpenTable Diner -
CopertaCoperta
430 reviews
$$$$
Italian | Uptown, Denver
Booked 27 times today

We went for our anniversary because it’s one of our favorite spots. This particular evening was definitely a night and a meal to remember thanks to the Coperta staff and service. More

OpenTable Diner -
D Bar DenverD Bar Denver
743 reviews
$$$$
Contemporary American | Uptown, Denver
Booked 29 times today

We had heard a lot about D Bar and finally got to try it for ourselves. I had a burger with fries and my wife ordered a salad, adding chicken. Our meals were prepared just as we had asked and were delicious. There were plenty of drink options, and we enjoyed our selections of beer and wine. Our server was helpful and attentive. The atmosphere, with high ceilings and large expanses of glass, was wonderful. Oh ya, and our shared dessert was out of this world! More

OpenTable Diner -
Humboldt Farm Fish WineHumboldt Farm Fish Wine
1047 reviews
$$$$
Contemporary American | Uptown, Denver
Booked 22 times today

I so enjoy the atrium room at Humboldt's! It is light and inviting. Even though tucked away from the crowd in the atrium, our server was attentive, gracious and timely. We enjoyed the fried brocolli the most, and the house bloody mary is a good, spicy start to Sunday brunch More

OpenTable Diner -
Ace Eat ServeAce Eat Serve
202 reviews
$$$$
Asian | Uptown, Denver

What a fabulous place to have fun and eat fantastic food! Happy Hour is amazing and the ping pong tables are a blast! Great for groups, special occasion and anyone that has an asian food fetish! More

OpenTable Diner -
Avenue Grill - DenverAvenue Grill - Denver
1484 reviews
$$$$
Contemporary American | Uptown, Denver
Booked 9 times today

Classic Denver establishment that has been around forever and for good reason. Solid food at a reasonable price in an upscale-casual environment. Ave Grill is a great business or date lunch spot. Plenty of designated restaurant-only parking is directly across 17th, which makes parking a breeze! Pretty traditional, comfort-foody fare. The pot stickers are awesome, BTW.. Warm, comfortable interior space. More

OpenTable Diner -
Tony P's Bar & Pizzeria - UptownTony P's Bar & Pizzeria - Uptown
51 reviews
$$$$
Italian | Uptown, Denver
Booked 2 times today

Took 11 incl 5 kids and all were very happy with service and make your own pizza for kids. Food was awesome and service was attentive and prompt. More

OpenTable Diner -
Jack's Uptown GrilleJack's Uptown Grille
39 reviews
$$$$
American | Uptown, Denver
Booked 2 times today

The shareable was sizable and delicious. We got the Captain crunch french toast sticks. The drinks were also good for the price. Overall, the food wasn't very exciting. It was average in flavor and made to sound more interesting than it was. More

OpenTable Diner -
Randolph's at Warwick Denver HotelRandolph's at Warwick Denver Hotel
661 reviews
$$$$
American | Uptown, Denver
Booked 7 times today

Excellent thanksgiving brunch. Hostess and hotel staff were amazing. Table staff need additional training on multi tasking More

OpenTable Diner -
Brik on YorkBrik on York
31 reviews
$$$$
Italian | Uptown, Denver
Booked 4 times today

Just as good the second time!! More

OpenTable Diner -
The Delectable EggThe Delectable Egg
7 reviews
$$$$
Breakfast | Uptown, Denver

The food was good but not great. Service started very slow but became better as the meal progressed. Pricing is average but menu selection is very diverse with unique selections. More

OpenTable Diner -
Las Delicas-UptownLas Delicas-Uptown
8 reviews
$$$$
Mexican | Uptown, Denver

THEY DO NOT HONOR OPEN TABLE RESERVATIONS. Don't make a reservation with them through Open Table. More

OpenTable Diner -

Uptown Denver Diners' Choice Winners

Uptown Denver's best restaurants based upon thousands of OpenTable diner reviews
Atelier by RadexAtelier by Radex
174 reviews
$$$$
French | Uptown, Denver
Booked 5 times today

I have always loved Radek Cerny's food. His seafood is outstanding and his sauces are perfection. The menu has lots of options for everyone. I especially love Atelier at lunch when the sun pours into the beautiful dining room. More

OpenTable Diner -
Bastien's RestaurantBastien's Restaurant
307 reviews
$$$$
Steakhouse | Uptown, Denver
Booked 1 time today

Food and atmosphere was great, I will return and it was very relaxing to listen to Frank Sinatra, the service could have been a lot better if the waitress was not rushing us to order. She was very rude and kept coming back to see if we were ready to order. We had an early reservstion just so we could take our time, and there was no need for the rush because there were very few people in the restaurant. More

OpenTable Diner -
Solera Restaurant & Wine BarSolera Restaurant & Wine Bar
1655 reviews
$$$$
Contemporary American | Uptown, Denver
Booked 5 times today

Solera has thoughtful, well-executed menu with excellent service. More

OpenTable Diner -
Beast and BottleBeast and Bottle
1031 reviews
$$$$
Contemporary American | Uptown, Denver
Booked 32 times today

Great interesting brunch options. Kids meals were lacking, and breakfast doesn’t include toast. However, all the food was great and the service was excellent. More

OpenTable Diner -
CopertaCoperta
430 reviews
$$$$
Italian | Uptown, Denver
Booked 27 times today

We went for our anniversary because it’s one of our favorite spots. This particular evening was definitely a night and a meal to remember thanks to the Coperta staff and service. More

OpenTable Diner -
D Bar DenverD Bar Denver
743 reviews
$$$$
Contemporary American | Uptown, Denver
Booked 29 times today

We had heard a lot about D Bar and finally got to try it for ourselves. I had a burger with fries and my wife ordered a salad, adding chicken. Our meals were prepared just as we had asked and were delicious. There were plenty of drink options, and we enjoyed our selections of beer and wine. Our server was helpful and attentive. The atmosphere, with high ceilings and large expanses of glass, was wonderful. Oh ya, and our shared dessert was out of this world! More

OpenTable Diner -
Ace Eat ServeAce Eat Serve
202 reviews
$$$$
Asian | Uptown, Denver

What a fabulous place to have fun and eat fantastic food! Happy Hour is amazing and the ping pong tables are a blast! Great for groups, special occasion and anyone that has an asian food fetish! More

OpenTable Diner -
Humboldt Farm Fish WineHumboldt Farm Fish Wine
1047 reviews
$$$$
Contemporary American | Uptown, Denver
Booked 22 times today

I so enjoy the atrium room at Humboldt's! It is light and inviting. Even though tucked away from the crowd in the atrium, our server was attentive, gracious and timely. We enjoyed the fried brocolli the most, and the house bloody mary is a good, spicy start to Sunday brunch More

OpenTable Diner -
Avenue Grill - DenverAvenue Grill - Denver
1484 reviews
$$$$
Contemporary American | Uptown, Denver
Booked 9 times today

Classic Denver establishment that has been around forever and for good reason. Solid food at a reasonable price in an upscale-casual environment. Ave Grill is a great business or date lunch spot. Plenty of designated restaurant-only parking is directly across 17th, which makes parking a breeze! Pretty traditional, comfort-foody fare. The pot stickers are awesome, BTW.. Warm, comfortable interior space. More

OpenTable Diner -
Jack's Uptown GrilleJack's Uptown Grille
39 reviews
$$$$
American | Uptown, Denver
Booked 2 times today

The shareable was sizable and delicious. We got the Captain crunch french toast sticks. The drinks were also good for the price. Overall, the food wasn't very exciting. It was average in flavor and made to sound more interesting than it was. More

OpenTable Diner -

Discover Uptown Denver

When it comes to enjoying the booming Denver culture, few neighborhoods can compete with exciting Uptown. Many restaurants in the area cater to the most straightforward tastes, with steakhouses that serve Colorado range beef and local pubs with standard bar food. However, many eateries also have diverse menu options inspired by the local immigrant history. The cheeseburger was invented in this town, and many eateries still serve their own variations of this American classic. Adventurous diners might want to try Rocky Mountain oysters. In addition, the Denver expansion has drawn in some of the best chef talent in the West.