Midtown Restaurants

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Best American Restaurants in Midtown

Three Kings Public House - The LoopThree Kings Public House - The Loop
(265)
$$$$
American | The Loop, Midtown
The Ritz-Carlton RestaurantThe Ritz-Carlton Restaurant
(135)
$$$$
American | Clayton, Midtown
AvenueAvenue
(436)
$$$$
American | Clayton, Midtown
Granite City Food & Brewery - Creve CoeurGranite City Food & Brewery - Creve Coeur
(97)
$$$$
American | Creve Coeur, Midtown
Herbie'sHerbie's
(1330)
$$$$
American | Clayton, Midtown
BoundaryBoundary
(517)
$$$$
American | Clayton, Midtown
TGI FRIDAYS - Creve CoeurTGI FRIDAYS - Creve Coeur
(27)
$$$$
American | Creve Coeur, Midtown
TGI FRIDAYS - Fairview HeightsTGI FRIDAYS - Fairview Heights
(21)
$$$$
American | Fairview Heights, Midtown
Annie Gunn'sAnnie Gunn's
(2611)
$$$$
American | St. Louis, Downtown
Spiro's - St. CharlesSpiro's - St. Charles
(53)
$$$$
American | Maryland Heights, West County
Anthony's BarAnthony's Bar
(151)
$$$$
American | Downtown St. Louis, Downtown
Frazer's Restaurant & LoungeFrazer's Restaurant & Lounge
(331)
$$$$
American | Soulard / Benton Park, Downtown
Billy G'sBilly G's
(87)
$$$$
American | Kirkwood, West County
Prasino - St. Charles, MOPrasino - St. Charles, MO
(1682)
$$$$
American | St. Charles, West County
Bishop's PostBishop's Post
(640)
$$$$
American | Chesterfield, West County
Balaban's - ChesterfieldBalaban's - Chesterfield
(333)
$$$$
American | Chesterfield, West County
Cardinals NationCardinals Nation
(411)
$$$$
American | Downtown St. Louis, Downtown

Best Italian Restaurants in Midtown

AceroAcero
(1065)
$$$$
Italian | Maplewood, Midtown
Café NapoliCafé Napoli
(1283)
$$$$
Italian | Clayton, Midtown
Katie's Pizza & Pasta Osteria - Rock HillKatie's Pizza & Pasta Osteria - Rock Hill
(759)
$$$$
Italian | Rock Hill, Midtown
IL Bel Lago - From the HillIL Bel Lago - From the Hill
(478)
$$$$
Italian | Creve Coeur, Midtown
SardellaSardella
(471)
$$$$
Italian | Clayton, Midtown
Giovanni's KitchenGiovanni's Kitchen
(546)
$$$$
Italian | Clayton, Midtown
Tavolo VTavolo V
(317)
$$$$
Italian | The Loop, Midtown
Maggiano's - St. LouisMaggiano's - St. Louis
(5592)
$$$$
Italian | Richmond Heights, Midtown
BassoBasso
(661)
$$$$
Italian | Clayton, Midtown
Napoli 2Napoli 2
(1317)
$$$$
Italian | Chesterfield, West County
Tony's - St. LouisTony's - St. Louis
(1280)
$$$$
Italian | St. Louis, Downtown
Charlie Gitto's 'On the Hill'Charlie Gitto's 'On the Hill'
(3623)
$$$$
Italian | The Hill, Downtown
Dominic's on the HillDominic's on the Hill
(557)
$$$$
Italian | The Hill, Downtown
Sapore Italian CafeSapore Italian Cafe
(167)
$$$$
Italian | Kirkwood, West County
Eleven Eleven MississippiEleven Eleven Mississippi
(3111)
$$$$
Italian | Soulard / Benton Park, Downtown
Charlie Gitto's at Hollywood CasinoCharlie Gitto's at Hollywood Casino
(1189)
$$$$
Italian | Maryland Heights, West County
Charlie Gitto's from the Hill - ChesterfieldCharlie Gitto's from the Hill - Chesterfield
(1481)
$$$$
Italian | Chesterfield, West County

Popular restaurants in St. Louis

Browse some of the most booked restaurants in St. Louis

Texas de Brazil - St Louis
(311)
$$$$
Steakhouse | St. Louis
Sardella
(417)
$$$$
Italian | Clayton
The Capital Grille - St. Louis - Clayton
(343)
$$$$
Steakhouse | Clayton
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Treat your taste buds: Explore Midtown restaurants.

Diners' Choice Winners: Best Overall

Midtown's best restaurants based upon thousands of OpenTable diner reviews
Acero1. Acero
1065 reviews
$$$$
Italian | Maplewood, Midtown

First time at Acero and will definitely return. What a wonderful surprise. The halibut on polenta with basil oil was cooked perfectly. Thoroughly enjoyed the tasting menu from the tomato salad to tagliatelle with sausage ragu. The dessert only added to the wonderful meal with blueberry cheesecake topped with berries and limoncello glaze. More

OpenTable Diner -
The Crossing2. The Crossing
1019 reviews
$$$$
French | Clayton, Midtown

The food was out of this world, and the service was even better. I would return in a flash. A little pricy but well worth it. More

OpenTable Diner -
Ruth's Chris Steak House - Clayton3. Ruth's Chris Steak House - Clayton
883 reviews
$$$$
Steakhouse | Clayton, Midtown

Fabulous restaurant with wonderful food and great service! It’s one of my very favorites! More

OpenTable Diner -
801 Fish - STL4. 801 Fish - STL
627 reviews
$$$$
Seafood | Clayton, Midtown

All staff very attentive. Waiter knew how to be properly available, and the ease of access of the location is awesome, Reminds me of upscale Florida. I enjoyed the Chilean Sea Bass, perfectly cooked and the raw oyster selection is amazing, realize your get what you pay for, gor for the more expensive and wow, its an adventure the different flavors. My favorite seafood restaurants in STL. More

OpenTable Diner -
Café Napoli5. Café Napoli
1283 reviews
$$$$
Italian | Clayton, Midtown

The service was outstanding and the food always the best. More

OpenTable Diner -

Discover Clayton

St. Louis, Missouri's inner-ring suburb of Clayton is known as not only the seat of St. Louis’s city government but also the spot for shopping, dining, and upscale hotels. A Taste of Clayton food festival is held here annually. Because “St. Louis’s second downtown” is a business hub, the dining atmosphere tends to be a hybrid of upscale and casual, with many restaurants that attract a business crowd. St. Louis barbecue is represented, along with burgers and Black Angus steaks. Visitors may be surprised to find many Italian influences along with a few bistros serving French-style food and more traditionally American pub food choices. The pedestrian-friendly neighborhood also offers sushi, vegetarian fare, and an espresso bar.