Midtown Restaurants

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Best American Restaurants in Midtown

Three Kings Public House - The LoopThree Kings Public House - The Loop
(262)
$$$$
American | The Loop, Midtown
The Ritz-Carlton RestaurantThe Ritz-Carlton Restaurant
(131)
$$$$
American | Clayton, Midtown
AvenueAvenue
(406)
$$$$
American | Clayton, Midtown
Granite City Food & Brewery - Creve CoeurGranite City Food & Brewery - Creve Coeur
(75)
$$$$
American | Creve Coeur, Midtown
Herbie'sHerbie's
(1279)
$$$$
American | Clayton, Midtown
BoundaryBoundary
(474)
$$$$
American | Clayton, Midtown
TGI FRIDAYS - Creve CoeurTGI FRIDAYS - Creve Coeur
(20)
$$$$
American | Creve Coeur, Midtown
TGI FRIDAYS - Fairview HeightsTGI FRIDAYS - Fairview Heights
(20)
$$$$
American | Fairview Heights, Midtown
Annie Gunn'sAnnie Gunn's
(2519)
$$$$
American | St. Louis, Downtown
Spiro's - St. CharlesSpiro's - St. Charles
(37)
$$$$
American | Maryland Heights, West County
Anthony's BarAnthony's Bar
(145)
$$$$
American | Downtown St. Louis, Downtown
Frazer's Restaurant & LoungeFrazer's Restaurant & Lounge
(300)
$$$$
American | Soulard / Benton Park, Downtown
Billy G'sBilly G's
(75)
$$$$
American | Kirkwood, West County
Prasino - St. Charles, MOPrasino - St. Charles, MO
(1606)
$$$$
American | St. Charles, West County
Bishop's PostBishop's Post
(573)
$$$$
American | Chesterfield, West County
Balaban's - ChesterfieldBalaban's - Chesterfield
(309)
$$$$
American | Chesterfield, West County
Cardinals NationCardinals Nation
(399)
$$$$
American | Downtown St. Louis, Downtown

Best Italian Restaurants in Midtown

AceroAcero
(1022)
$$$$
Italian | Maplewood, Midtown
Café NapoliCafé Napoli
(1240)
$$$$
Italian | Clayton, Midtown
Katie's Pizza & Pasta Osteria - Rock HillKatie's Pizza & Pasta Osteria - Rock Hill
(694)
$$$$
Italian | Rock Hill, Midtown
IL Bel Lago - From the HillIL Bel Lago - From the Hill
(448)
$$$$
Italian | Creve Coeur, Midtown
SardellaSardella
(418)
$$$$
Italian | Clayton, Midtown
Giovanni's KitchenGiovanni's Kitchen
(508)
$$$$
Italian | Clayton, Midtown
Tavolo VTavolo V
(289)
$$$$
Italian | The Loop, Midtown
BassoBasso
(637)
$$$$
Italian | Clayton, Midtown
Napoli 2Napoli 2
(1266)
$$$$
Italian | Chesterfield, West County
Tony's - St. LouisTony's - St. Louis
(1226)
$$$$
Italian | St. Louis, Downtown
Charlie Gitto's 'On the Hill'Charlie Gitto's 'On the Hill'
(3456)
$$$$
Italian | The Hill, Downtown
Dominic's on the HillDominic's on the Hill
(540)
$$$$
Italian | The Hill, Downtown
Sapore Italian CafeSapore Italian Cafe
(149)
$$$$
Italian | Kirkwood, West County
Eleven Eleven MississippiEleven Eleven Mississippi
(3024)
$$$$
Italian | Soulard / Benton Park, Downtown
Charlie Gitto's at Hollywood CasinoCharlie Gitto's at Hollywood Casino
(1137)
$$$$
Italian | Maryland Heights, West County
Charlie Gitto's from the Hill - ChesterfieldCharlie Gitto's from the Hill - Chesterfield
(1407)
$$$$
Italian | Chesterfield, West County

Popular restaurants in St. Louis

Browse some of the most booked restaurants in St. Louis

Texas de Brazil - St Louis
(142)
$$$$
Steakhouse | St. Louis
Sardella
(466)
$$$$
Italian | Clayton
The Capital Grille - St. Louis - Clayton
(409)
$$$$
Steakhouse | Clayton
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Treat your taste buds: Explore Midtown restaurants.

Diners' Choice Winners: Best Overall

Midtown's best restaurants based upon thousands of OpenTable diner reviews
Acero1. Acero
1022 reviews
$$$$
Italian | Maplewood, Midtown

Great food. Server was really professional. Took to long. Arrived at 7 and left at 10. Granted we had a meat and cheese plate plus 4 more courses....still it was a little slow in between courses. Thanks for a great experience. More

OpenTable Diner -
The Crossing2. The Crossing
966 reviews
$$$$
French | Clayton, Midtown

Spectacular food, wonderful service. The food presentation was as beautiful as it was delicious More

OpenTable Diner -
Katie's Pizza & Pasta Osteria - Rock Hill3. Katie's Pizza & Pasta Osteria - Rock Hill
694 reviews
$$$$
Italian | Rock Hill, Midtown

Celebrating my two staff members for Administrative Professional Week. More

OpenTable Diner -
Truffles - St. Louis4. Truffles - St. Louis
778 reviews
$$$$
Contemporary American | Clayton, Midtown

Great food and incredible service. Would highly recommend for special occasions. More

OpenTable Diner -
801 Chophouse - St. Louis5. 801 Chophouse - St. Louis
1303 reviews
$$$$
Steakhouse | Clayton, Midtown

Business meeting More

OpenTable Diner -

Discover Clayton

St. Louis, Missouri's inner-ring suburb of Clayton is known as not only the seat of St. Louis’s city government but also the spot for shopping, dining, and upscale hotels. A Taste of Clayton food festival is held here annually. Because “St. Louis’s second downtown” is a business hub, the dining atmosphere tends to be a hybrid of upscale and casual, with many restaurants that attract a business crowd. St. Louis barbecue is represented, along with burgers and Black Angus steaks. Visitors may be surprised to find many Italian influences along with a few bistros serving French-style food and more traditionally American pub food choices. The pedestrian-friendly neighborhood also offers sushi, vegetarian fare, and an espresso bar.