Diners' Choice: Innovative restaurants in Jacksonville

OpenTable

Updated July 05, 2025

Looking for the best restaurants that are fit for foodies in Jacksonville? You’re in the right place. Each month, OpenTable analyzes nearly 2 million global diner reviews from the past four months. We sort the results by location and category to help you discover new favorite restaurants. It's a great partnership: you reserve, eat, and review. We listen...and deliver the results for all to benefit. Enjoy!

Rue Saint-Marc

4.9

4.9 (1797)

$50 and over

Contemporary European

Jacksonville

About the restaurant

Rue Saint-Marc is a modern restaurant serving French inspired cuisine in the San Marco neighborhood. We have an extensive cocktail program and a unique wine and craft beer list. The ambiance is stylish while still being quite comfortable. Seating includes tufted leather booths, handmade wooden tables, a beautiful bar-height communal table, and an outdoor patio. An open kitchen allows guests to view the chefs in action.

Top review

Kirkland

Dined 4 days ago

Excellent service with amazing food in a quaint, upscale atmosphere.

13 Gypsies

4.8

4.8 (599)

$31 to $50

Spanish

Jacksonville

About the restaurant

13 Gypsies is a cozy, intimate Spanish tapas restaurant. You can also find the influence of other cuisines throughout the menu. Primarily utilizing Spanish techniques to prepare both creative and classic renditions of Spanish dishes, Chef Howard and Chef Kevan operate a true craft kitchen. The two of them prepare and cook most everything from scratch including breads, cured meats, cheeses, sausages, spice blends, pickled vegetables, and desserts. This practice of making nearly everything in house promotes waste-free cooking and higher quality food. Our wines are mainly from Spain, and our beer is Florida local. We are located in a two-story Spanish-style building built in 1923 by Henrietta Dozier, Jacksonville's only female architect in the early part of the 20th century. You will find eclectic, maximalist religious iconography adorning the walls and original floor tile. We have few tables, so reservations are highly recommended. Last seating is an hour and a half before closing time.

Top review

ellenVIP

Dined 2 days ago

Culinary excellence, from salad to dessert. Treat yourself.

M Brothers at Mayo

4.7

4.7 (535)

$50 and over

Seafood

Jacksonville

About the restaurant

M Brothers at Mayo is a hidden gem tucked inside Jacksonville’s Mayo Clinic—a delightful reprieve where culinary excellence meets refined hospitality. A Medure Brothers Culinary Concept by acclaimed chefs Matthew and David Medure, M Brothers is led by Executive Chef Thomas Rivers and offers a sophisticated dining experience on Mayo Clinic's campus.

Enjoy globally inspired cuisine crafted with seasonal ingredients, and don’t miss our monthly Culinary Passport tasting menus, where we explore flavors from a different region of the world each month.

Visit our lounge for a handcrafted cocktail or select a bottle from our extensive wine list. Join us for Lunch Monday–Friday and Dinner Monday–Saturday. Unwind during Happy Hour in the lounge, Monday–Friday from 4–6 PM.

Whether you're sampling guest favorites like our burrata appetizer, savory shrimp étouffée, or a seasonal chef-driven entrée, M Brothers is a destination worth discovering.

Top review

RussellVIP

Dined 6 days ago

We had such an amazing experience at M Brothers at Mayo. The staff is amazing. The food was exceptional, and the restaurant was beautiful.

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The Melting Pot - Jacksonville

4.6

4.6 (975)

$31 to $50

Fondue

Baymeadows

About the restaurant

Enjoy an unforgettable interactive dining experience with friends and family with fondue at The Melting Pot in Jacksonville, FL. We believe in celebrating the everyday, so you don’t need a special reason to come out for our delicious menu offerings. Whether you’re here for drinks, cheese, and chocolate, or you want to dig into our four-course fondue experience, we know you’ll love every bite! From artisan cheeses to our decadent chocolate fondue desserts, there is something to tickle your taste buds in each pot. Let our friendly staff help you choose the right fondue experience for your table tonight.

Top review

AdrienneVIP

Dined on Jun 25, 2025

Our server was amazing and very helpful with two food allergies!

BJ's Restaurant & Brewhouse - Jacksonville

4.6

4.6 (182)

$30 and under

American

Baymeadows

About the restaurant

Time counts at BJ's Restaurant & Brewhouse. Since our humble beginnings back in 1978, we've continued to refine our brewhouse experience to make BJ's a place where you can make the most of any meal. We want BJ's to be a place where the moment you leave is the moment you plan on coming back. We pride ourselves in our craft and attention to detail. Our guests come here for our award-winning handcrafted beer. They come here for the Southern California twist we've put on the Chicago-style deep dish pizza. And they come here for our Pizookies®, our world-renowned dessert. But above all we know people come here to make their good times better. So in many ways we haven't just crafted a brand, but a mindset. And our guests are the reason for this. And it's because of them we're continually striving to make sure every moment they choose to spend with us counts. Welcome to BJ's, a restaurant with a Brewhouse soul.

Top review

Frank

Dined on Jun 29, 2025

Great sports bar to visit. Good food and drinks. Or service and server were great and responsive.

Odd Birds Kitchen and Cocktail Lounge

4.6

4.6 (16)

$30 and under

Latin American

St Johns

About the restaurant

Odd Birds Cocktail Lounge & Kitchen, located just east of the Bridge of Lions, is where the unexpected meets the unforgettable. In our fun and eclectic setting, oddness rules, and we embrace it with bold flavors, adventurous cocktails, and an atmosphere that keeps you coming back for more. Our Latin fusion menu is crafted entirely in-house, blending tradition with creativity for a dining experience that’s as unique as our vibe. But what truly sets us apart? Our craft cocktails—thoughtfully curated to push the boundaries of your palate. We use rare spirits, house-made syrups, and innovative techniques to create drinks that take you out of your comfort zone and into a world of flavor. Whether you’re here for the drinks, the food, or just the good energy, Odd Birds is a place to celebrate individuality, explore the unexpected, and raise a glass to the delightfully strange. Cheers to being odd! 🦉🍸

Top review

James

Dined 2 days ago

Great time at the Speak Easy! Relaxed atmosphere and the drinks and service were excellent.

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Experience

Charlotte 33 Speakeasy

CatalunaJax

4.6

4.6 (323)

$31 to $50

European

Baymeadows

About the restaurant

Discover a culinary voyage like never before at Jacksonville's latest sensation! This groundbreaking restaurant and bar seamlessly blend the rich flavors of Italian, Spanish, and Mediterranean cuisine within the opulent confines of one of the city's most breathtaking dining spaces. Boasting over 6,000 square feet of luxurious ambiance, the venue underwent a multi-million-dollar transformation, culminating in the creation of two exquisite bars, an enchanting 250-seat dining room, and captivating lighting and decor. The carefully curated menu promises a gastronomic symphony featuring succulent steaks, fresh seafood, and artisanal pasta, complemented by an international selection of wines and cocktails that span the spectrum from classic to cutting-edge, including both clarified and craft concoctions. Prepare to embark on a culinary journey that transcends boundaries and sets a new standard for dining excellence in Jacksonville.

Top review

Kristin

Dined 1 day ago

My husband and I visited over 4th of July weekend. It was quiet and just a beautiful atmosphere. We got the Brussels, a pita and spreads board (outstanding) and we split a beef tenderloin was was cooked perfect medium. I had a lovely craft cocktail. We will 1000 percent be back for a lovely night together. Perfect for an adult night out.

P.F. Chang's - Jacksonville

4.5

4.5 (366)

$30 and under

Chinese

Baymeadows

About the restaurant

We are an Asian & Chinese restaurant offering dine-in, takeout, to-go, delivery, and catering. Make a reservation online to dine in. Order Asian and Chinese food delivery, takeout, and catering online or through the P.F. Chang's mobile app. Let us cater the perfect feast for you - corporate office catering menus are also available. P.F. Chang's offers a variety of signature Asian, Thai, Korean, Japanese, Mongolian, and Chinese food dishes including Chicken Lettuce Wraps, Chicken Pad Thai, Signature Lo Mein, Fried Rice, Mongolian Beef, Chang's Spicy Chicken, and Pork and Shrimp Dumplings. Order online for sushi delivery and takeout. Many gluten-free and vegetarian menu items are available. Try our seasonal cocktails and seasonal menu items.

Top review

TimVIP

Dined on Jun 26, 2025

If you have shellfish allergies, ask for their special menu listing items safe to order. It is not intuitive on the main menu since sauces can frequently use oyster sauce and cooking methods can introduce cross contamination. The special menu is a nice innovation.

True Food Kitchen - Jacksonville

4.5

4.5 (1482)

$30 and under

American

Baymeadows

About the restaurant

True Food Kitchen is a chef-driven restaurant and scratch bar that was founded by Dr. Andrew Weil, the pioneer of integrative medicine, to provide food that tastes great and is good for you. Our menu features food and drinks crafted with nutrient-dense ingredients and carefully sourced proteins from the world’s most responsible and sustainable growers, farmers and producers. Expand your palate with our Edamame Dumplings, grab a bite of comfort food with our Grass-fed Burger or Lasagna Bolognese, or enjoy lighter fare with our O.G. Tuscan Kale Salad with Grilled Sustainable Salmon. Regardless of the occasion, we know our Jacksonville guests leave feeling energized, satisfied and most importantly, feeling great. Located in Jacksonville at The St. Johns Town center. New flavors, new combinations, new obsessions. Come see us for something completely new and delicious.

Top review

CindyVIP

Dined 5 days ago

Second time there in a week. My home town doesn’t have this restaurant and I love their food. It’s clean healthy food. Service was good as always.

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Whiskey Cake - Jacksonville

4.3

4.3 (296)

$30 and under

American

Baymeadows

About the restaurant

Our menus are all about bold, seasonal flavors, using ingredients from the best local farmers, ranchers, and growers—because fresh just hits different. Behind the bar, we’re mixing up garden-to-glass cocktails with house-made syrups and fresh juices, plus a barrel select whiskey program that’s all about the good stuff. Whiskey Cake is where great food and good company always come together.

Top review

David

Dined on Jun 24, 2025

Excellent food, service & ambience. Always enjoyed the San Antonio location. Excited to now have a location here in Jacksonville.

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