Enable JavaScript to run this app.
Skip to main content
OpenTable logo
Casa Santo Stefano, Ybor City, FL

Casa Santo Stefano

4.7 (3914)
$30 and under
Sicilian
1607 N 22nd St, Ybor City, FL 33605

Make a reservation

2 people
7:30 PM
Booked 38 times today

About this restaurant

  • Good for special occasions
  • Charming
  • Good for groups
Benvenuti! Casa Santo Stefano is a Sicilian restaurant from the Gonzmart family, owners of the 1905 Family Of Restaurants. The lunch and dinner menus feature maccheroni (pasta), steaks, seafood, scacciata, salads, soups, desserts and hundreds of Sicilian wines. Curbside takeout is available by calling the main phone number. The rooftop Santo's Drinkeria also is open.

Housed in a beautifully re-imagined former 1925 Ybor City macaroni factory, the restaurant is a look back to Sunday suppers, simpler times and shared stories.

Dress code: Casa Santo Stefano often is visited for celebrations and special occasion meals, so it is common for our guests to sport formal wear in the dining room. We welcome everyone, but politely ask that men wear sleeves at Casa Santo Stefano.

Dining areas

Additional information

  • Dining style
    Casual Dining
  • Price
    $30 and under
  • Cuisines
    Sicilian
  • Hours of operation
    Lunch Daily 11:00 am–4:00 pm Dinner Daily 4:00 pm–10:00 pm
  • Phone number
  • Payment options
    AMEX, Discover, Mastercard, Visa
  • Dress code
    Business Casual
  • Catering
    Casa Santo Stefano offers a full takeout catering menu.
  • Private party facilities
    Call the Columbia Restaurant private dining department at 813.248.4961 and specify Casa Santo Stefano.
  • Delivery & takeout
  • Neighborhood
    Ybor City
  • Cross street
    Between 5th Avenue and 7th Avenue
  • Parking details
    Park free across from the restaurant in the large Columbia lot between 21st and 22nd streets. The Columbia also has several other free lots nearby. There is a new drop-off drive at 5th Avenue and 22nd Street, right next to the restaurant. (Look for the boar statue and 1925 Model T.)
  • Public transit
    The TECO Streetcar stops at Centennial Park, 20th Street and 8h Avenue. This streetcar runs between Downtown Tampa and Ybor City.
  • Additional
    Bar/Lounge, Beer, Chef's Table, Cigar Room, Cocktails, Counter Seating, Full Bar, Outdoor Smoking Area, Takeout, View, Wheelchair Access, Wine

Ask Concierge
AI Beta

Our AI assistant, Concierge, is here to answer your questions about this restaurant.

What 3,914 people are saying

Casa Santo Stefano reviews from people who’ve dined at this restaurant. Based on recent rating.

Overall ratings and reviews

Reviews can only be made by diners who have eaten at this restaurant

4.7
4.7 based on recent ratings
  • 4.7Food
  • 4.7Service
  • 4.8Ambience
  • 4.6Value

NoiseModerate

Review summary

AI-generated from verified diner reviews
Casa Santo Stefano in Tampa offers a "great dining experience" with "excellent food" and "superb service." Guests appreciate the restaurant's "beautiful decor" and "inviting atmosphere." The menu features authentic Sicilian dishes, with recommendations for the "grouper" and "pasta dishes." The rooftop bar adds a charming touch.
3,914 Reviews
  1. Tony VIP

    Tampa / Central Florida West9 reviews

    4.0

    Dined 1 day ago

    1. Overall 4
    2. Food 4
    3. Service 5
    4. Ambience 5
    Santo Stefano remains one of the best Italian restaurants in Tampa—great atmosphere, impeccable service, and consistently delicious meals. I’ve been a loyal customer since they opened, and their black ink squid pasta with octopus was hands down one of the best dishes in Tampa. I was heartbroken to discover it’s been removed from the menu after several months away. It was a true standout that showcased their culinary creativity. While the rest of the menu is still very good, I truly hope they consider bringing this incredible dish back. It’s sorely missed by those of us who loved it.

    Is this helpful?

  2. Kathe

    Tampa / Central Florida West3 reviews

    5.0

    Dined 5 days ago

    1. Overall 5
    2. Food 5
    3. Service 5
    4. Ambience 5
    Carlos was outstanding, and made our visit memorable for our birthday celebration!

    Is this helpful?

  3. Mike

    Chicago / Illinois16 reviews

    5.0

    Dined 7 days ago

    1. Overall 5
    2. Food 5
    3. Service 5
    4. Ambience 5
    First time there - The food was amazing and service absolutely fantastic!
    Casa Santo StefanoResponded 5 days ago
    Glad your first visit went so well, Mike!

    Is this helpful?

  4. Janice

    Tampa / Central Florida West19 reviews

    4.0

    Dined on June 28, 2025

    1. Overall 4
    2. Food 4
    3. Service 5
    4. Ambience 3
    Nice atmosphere. Carlos was an excellent server. Thanks
    Casa Santo StefanoResponded 5 days ago
    Thank you for taking time to praise Carlos's service, Janice. Hope you get to visit again soon.

    Is this helpful?

  5. Nancy

    Miami - Dade1 review

    5.0

    Dined on June 27, 2025

    1. Overall 5
    2. Food 5
    3. Service 5
    4. Ambience 5
    Food, service and ambience was excellent. Highly recommend this restaurant.
    Casa Santo StefanoResponded 5 days ago
    Thank you for your five-star rating, Nancy! We look forward to your next visit to Casa Santo Stefano.

    Is this helpful?

  6. Rick

    Tampa / Central Florida West18 reviews

    5.0

    Dined on June 27, 2025

    1. Overall 5
    2. Food 5
    3. Service 5
    4. Ambience 5
    We had great meal an excellent service! We will definitely be back
    Casa Santo StefanoResponded 5 days ago
    Thank you for your five-star rating, Rick! We look forward to your next visit to Casa Santo Stefano.

    Is this helpful?

  7. Roland

    Tampa / Central Florida West1 review

    5.0

    Dined on June 25, 2025

    1. Overall 5
    2. Food 5
    3. Service 5
    4. Ambience 5
    Absolutely love this place. The food and atmosphere are perfect for a date night. Our server, Pablo, has extensive knowledge about the wines and what paired well with the amazing filet I ordered.

    Is this helpful?

  8. Sergio

    Tampa / Central Florida West2 reviews

    5.0

    Dined on June 22, 2025

    1. Overall 5
    2. Food 4
    3. Service 5
    4. Ambience 5
    Overall great experience. Great service, good food, nice atmosphere.

    Is this helpful?

  9. Sue VIP

    Tampa / Central Florida West76 reviews

    5.0

    Dined on June 22, 2025

    1. Overall 5
    2. Food 5
    3. Service 5
    4. Ambience 5
    Always the best food and service! The vanilla cake with lemon is perfection.

    Is this helpful?

  10. Eileen

    Tampa / Central Florida West3 reviews

    5.0

    Dined on June 22, 2025

    1. Overall 5
    2. Food 5
    3. Service 5
    4. Ambience 5
    The food was super, the service amazing! It was our granddaughters birthdays and they treated them like queens. Carlos is magnificent. What a great place!

    Is this helpful?

FAQs

Casa Santo Stefano offers takeout which you can order by calling the restaurant at (813) 248-1925.

Casa Santo Stefano is rated 4.7 stars by 3914 OpenTable diners.

Yes, you can generally book this restaurant by choosing the date, time and party size on OpenTable.

  1. Home
  2. United States
  3. Tampa / Central Florida West
  4. Tampa
  5. Ybor City

Make a reservation

2 people
7:30 PM
Booked 38 times today
Google Map for Casa Santo Stefano

1607 N 22nd St, Ybor City, FL 33605

Dining areas

Additional information

  • Cross street
    Between 5th Avenue and 7th Avenue
  • Neighborhood
    Ybor City
  • Hours of operation
    Lunch Daily 11:00 am–4:00 pm Dinner Daily 4:00 pm–10:00 pm
  • Price
    $30 and under
  • Cuisines
    Sicilian
  • Dining style
    Casual Dining
  • Dress code
    Business Casual
  • Parking details
    Park free across from the restaurant in the large Columbia lot between 21st and 22nd streets. The Columbia also has several other free lots nearby. There is a new drop-off drive at 5th Avenue and 22nd Street, right next to the restaurant. (Look for the boar statue and 1925 Model T.)
  • Public transit
    The TECO Streetcar stops at Centennial Park, 20th Street and 8h Avenue. This streetcar runs between Downtown Tampa and Ybor City.
  • Payment options
    AMEX, Discover, Mastercard, Visa
  • Additional
    Bar/Lounge, Beer, Chef's Table, Cigar Room, Cocktails, Counter Seating, Full Bar, Outdoor Smoking Area, Takeout, View, Wheelchair Access, Wine
  • Delivery & takeout
  • Phone number
  • Catering
    Casa Santo Stefano offers a full takeout catering menu.
  • Private party facilities
    Call the Columbia Restaurant private dining department at 813.248.4961 and specify Casa Santo Stefano.
OpenTable
  • About Us
  • Blog
  • Careers
  • Press
More
Businesses
  • Restaurant Management Solutions
  • Restaurant Reservation Software
  • Restaurant Marketing Software
  • Restaurant Event Software
  • OpenTable For Restaurants
  • OpenTable For Restaurant Groups
  • Restaurant Resources
  • OpenTable Pricing & Plans
Join us on
  • Privacy Policy
  • Terms of Use
  • Cookies and Interest-Based Ads
  • Do Not Sell or Share My Personal Information
  • Cookie Preferences
Copyright © 2025 OpenTable, Inc. 1 Montgomery St Ste 500, San Francisco CA 94104 - All rights reserved.
OpenTable is part of Booking Holdings, the world leader in online travel and related services.
Booking Logo
Priceline Logo
KAYAK Logo
Agoda Logo
OpenTable Logo