Enable JavaScript to run this app.
Skip to main content
OpenTable logo
Casa Santo Stefano, Ybor City, FL

Casa Santo Stefano

4.8 (3848)
$30 and under
Sicilian
1607 N 22nd St, Ybor City, FL 33605

Make a reservation

2 people
10:30 PM
Booked 66 times today

About this restaurant

  • Good for special occasions
  • Charming
  • Neighborhood gem
Benvenuti! Casa Santo Stefano is a Sicilian restaurant from the Gonzmart family, owners of the 1905 Family Of Restaurants. The lunch and dinner menus feature maccheroni (pasta), steaks, seafood, scacciata, salads, soups, desserts and hundreds of Sicilian wines. Curbside takeout is available by calling the main phone number. The rooftop Santo's Drinkeria also is open.

Housed in a beautifully re-imagined former 1925 Ybor City macaroni factory, the restaurant is a look back to Sunday suppers, simpler times and shared stories.

Dress code: Casa Santo Stefano often is visited for celebrations and special occasion meals, so it is common for our guests to sport formal wear in the dining room. We welcome everyone, but politely ask that men wear sleeves at Casa Santo Stefano.

Dining areas

Additional information

  • Dining style
    Casual Dining
  • Price
    $30 and under
  • Cuisines
    Sicilian
  • Hours of operation
    Lunch Daily 11:00 am–4:00 pm Dinner Daily 4:00 pm–10:00 pm
  • Phone number
  • Payment options
    AMEX, Discover, Mastercard, Visa
  • Dress code
    Business Casual
  • Catering
    Casa Santo Stefano offers a full takeout catering menu.
  • Private party facilities
    Call the Columbia Restaurant private dining department at 813.248.4961 and specify Casa Santo Stefano.
  • Delivery & takeout
  • Neighborhood
    Ybor City
  • Cross street
    Between 5th Avenue and 7th Avenue
  • Parking details
    Park free across from the restaurant in the large Columbia lot between 21st and 22nd streets. The Columbia also has several other free lots nearby. There is a new drop-off drive at 5th Avenue and 22nd Street, right next to the restaurant. (Look for the boar statue and 1925 Model T.)
  • Public transit
    The TECO Streetcar stops at Centennial Park, 20th Street and 8h Avenue. This streetcar runs between Downtown Tampa and Ybor City.
  • Additional
    Bar/Lounge, Beer, Chef's Table, Cigar Room, Cocktails, Counter Seating, Full Bar, Outdoor Smoking Area, Takeout, View, Wheelchair Access, Wine

What 3,848 people are saying

Casa Santo Stefano reviews from people who’ve dined at this restaurant. Based on recent rating.

Overall ratings and reviews

Reviews can only be made by diners who have eaten at this restaurant

4.8
4.8 based on recent ratings
  • 4.7Food
  • 4.7Service
  • 4.8Ambience
  • 4.6Value

NoiseModerate

Loved For

  • Tampa

    Best Ambiance

Review summary

AI-generated from verified diner reviews
Casa Santo Stefano offers a vibrant dining experience with "excellent Sicilian food" and "outstanding service." Guests praise the "beautiful decor" and "lovely rooftop bar," making it a perfect spot for any occasion. Consistent favorites include the eggplant appetizer, sea bass, and pistachio cheesecake. "A true gem" in Tampa's Ybor City.

3,848 Reviews
  1. Jesus

    Tampa3 reviews

    4.0

    Dined 2 days ago

    1. Overall 4
    2. Food 5
    3. Service 3
    4. Ambience 5
    Our service suffered because our server was too busy with all the tables he was responsible for.
    Casa Santo StefanoResponded 1 day ago
    Thank you for your feedback, Jesus. Much appreciated. Sorry that your service did not meet expectations.

    Is this helpful?

  2. Peter VIP

    New York City34 reviews

    5.0

    Dined 3 days ago

    1. Overall 5
    2. Food 5
    3. Service 5
    4. Ambience 5
    Our waitress Theo made the night - awesome wait service and ambience and mostly food was awesome. Thank you
    Casa Santo StefanoResponded 2 days ago
    Peter, thank you for the kind words and thank you for your five-star rating! We look forward to your next visit to Casa Santo Stefano.

    Is this helpful?

  3. george

    Tampa17 reviews

    5.0

    Dined 5 days ago

    1. Overall 5
    2. Food 5
    3. Service 5
    4. Ambience 5
    We totally in joyed our evening. Starting with the bar area. Then with our server Mattie who was delightful. She was very friendly and did rush us to order our meals  while we are eating our appetizers. The total experience was phenomenal.
    Casa Santo StefanoResponded 3 days ago
    Glad the team could provide such a wonderful experience, George. Thank you for sharing.

    Is this helpful?

  4. Samantha

    Nashville19 reviews

    3.0

    Dined 5 days ago

    1. Overall 3
    2. Food 3
    3. Service 3
    4. Ambience 4
    We have been here before while on vacation in Tampa and it was a good experience. This time wasn’t quite as good. It was pretty busy since it was me a weekend so we expected some delays hit to wait 20 minutes just to get water was too much. Our waiter was seemed lovely and like she was trying. She may have been new but she seemed overwhelmed. She didn’t know the wine menu when we asked questions. My gnocchi dish was good but so salty I couldn’t finish it. Everything just took so long to get, water, bread, we would not see our waiter for long periods. At one point I asked a bus boy to please bring me some Parmesan cheese and I appreciated his willingness to help. We know our waiter was trying hard so we tried to be understanding. She just needs more time to get the hang of it. But the lack of efficient service might make me reconsider where to dorm st during our next trip here. I would definitely avoid on a weekend.
    Casa Santo StefanoResponded 3 days ago
    Samantha, we apologize for our poor service. Thank you for your feedback - and for your patience. We'll share with our operations team for their response. Everything you mentioned is absolutely fixable.

    Is this helpful?

  5. Meredith

    Tampa1 review

    5.0

    Dined 5 days ago

    1. Overall 5
    2. Food 5
    3. Service 5
    4. Ambience 5
    Always have great food and service here. Go early and enjoy a drink at the bar first.
    Casa Santo StefanoResponded 3 days ago
    Great tips. Love the vibe at the bar. Glad you did, too, Meredith. Thanks for your lovely comments.

    Is this helpful?

  6. Richard VIP

    Tampa39 reviews

    5.0

    Dined 7 days ago

    1. Overall 5
    2. Food 5
    3. Service 5
    4. Ambience 5
    Great place. Been there a dozen times. Always great
    Casa Santo StefanoResponded 3 days ago
    Thank you for your five-star rating! So glad you enjoyed and are a continued patron. We look forward to your next visit to Casa Santo Stefano.

    Is this helpful?

  7. Douglas

    Tampa14 reviews

    5.0

    Dined 7 days ago

    1. Overall 5
    2. Food 5
    3. Service 5
    4. Ambience 5
    The grilled sea bass is always fresh and perfectly prepared. I always enjoy the excellent service.
    Casa Santo StefanoResponded 2 days ago
    The sea bass is a customer favorite. So glad it's yours as well, Douglas!

    Is this helpful?

  8. Celeste

    Tampa4 reviews

    5.0

    Dined on April 30, 2025

    1. Overall 5
    2. Food 5
    3. Service 5
    4. Ambience 5
    Great dinner with long time friends. 2 out of 3 of us are Italian, and the red sauce with meatballs, pork, sausage and hard boiled egg was just like our nonnas used to make. Mateo our service was a pleasant and attentive as possible. Looking forward to the return of the squid ink pasta!
    Casa Santo StefanoResponded 2 days ago
    Thank you for your outstanding rating and wonderful compliments, Celeste. We're working to bring back the squid ink pasta. We look forward to your next visit to Casa Santo Stefano.

    Is this helpful?

  9. SUSAN VIP

    Tampa1 review

    3.0

    Dined on April 28, 2025

    1. Overall 3
    2. Food 5
    3. Service 3
    4. Ambience 3
    Food is spectacular. Service is inconsistent. We've been a few times and most recently, service was not great. Waters empty, had to ask for refills multiple times, didn't get asked if we wanted parm with pasta, wine went without an ask if we wanted another glass until too late into our meal, etc. Also, the floors are incredibly slippery and dangerous. Even trying my best to step carefully, I still slipped and fell.
    Casa Santo StefanoResponded on April 30, 2025
    Thank you for your feedback, Susan. We'll work hard to improve, thanks to your comments.

    Is this helpful?

  10. Joe

    New York City1 review

    5.0

    Dined on April 27, 2025

    1. Overall 5
    2. Food 5
    3. Service 5
    4. Ambience 5
    Once again, Casa Santo Stefano has distinguished itself as a rare exemplar of culinary and hospitality excellence. From the moment of entry, the ambiance is nothing short of transcendent—an exquisite balance of warmth, elegance, and authenticity that evokes both nostalgia and sophistication. The carefully curated interiors, ambient lighting, and impeccable attention to detail cultivate a setting that is as emotionally resonant as it is aesthetically refined. The cuisine is a masterclass in tradition elevated by contemporary artistry. Every dish is executed with precision, using ingredients of exceptional quality, resulting in a harmonious interplay of bold, authentic flavors and nuanced textures. It is evident that the culinary team operates with a profound respect for heritage, combined with the creative audacity necessary to achieve true excellence. Integral to the evening’s success was the impeccable service provided by our waiter, Rich. His consummate professionalism, intuitive attentiveness, and encyclopedic knowledge of the menu elevated the experience immeasurably. Rich anticipated needs with unobtrusive grace, offered insightful recommendations, and engaged with a warmth and authenticity that epitomize the highest ideals of hospitality. Casa Santo Stefano transcends the conventional dining experience; it is a celebration of culture, craft, and genuine human connection. In an era often marked by superficiality, this establishment stands as a beacon of authenticity and refinement. I offer my highest and most enthusiastic recommendation. Casa Santo Stefano is not merely a restaurant—it is an extraordinary experience worthy of both reverence and frequent return.
    Casa Santo StefanoResponded on April 30, 2025
    Thank you for your outstanding rating and wonderful compliments, Joe. We are overwhelmed by the generosity. We look forward to your next visit to Casa Santo Stefano.

    Is this helpful?

FAQs

Casa Santo Stefano offers takeout which you can order by calling the restaurant at (813) 248-1925.

Casa Santo Stefano is rated 4.8 stars by 3848 OpenTable diners.

Yes, you can generally book this restaurant by choosing the date, time and party size on OpenTable.

  1. Home
  2. United States
  3. Tampa / Central Florida West
  4. Tampa
  5. Ybor City

Make a reservation

2 people
10:30 PM
Booked 66 times today
Google Map for Casa Santo Stefano

1607 N 22nd St, Ybor City, FL 33605

Dining areas

Additional information

  • Cross street
    Between 5th Avenue and 7th Avenue
  • Neighborhood
    Ybor City
  • Hours of operation
    Lunch Daily 11:00 am–4:00 pm Dinner Daily 4:00 pm–10:00 pm
  • Price
    $30 and under
  • Cuisines
    Sicilian
  • Dining style
    Casual Dining
  • Dress code
    Business Casual
  • Parking details
    Park free across from the restaurant in the large Columbia lot between 21st and 22nd streets. The Columbia also has several other free lots nearby. There is a new drop-off drive at 5th Avenue and 22nd Street, right next to the restaurant. (Look for the boar statue and 1925 Model T.)
  • Public transit
    The TECO Streetcar stops at Centennial Park, 20th Street and 8h Avenue. This streetcar runs between Downtown Tampa and Ybor City.
  • Payment options
    AMEX, Discover, Mastercard, Visa
  • Additional
    Bar/Lounge, Beer, Chef's Table, Cigar Room, Cocktails, Counter Seating, Full Bar, Outdoor Smoking Area, Takeout, View, Wheelchair Access, Wine
  • Delivery & takeout
  • Phone number
  • Catering
    Casa Santo Stefano offers a full takeout catering menu.
  • Private party facilities
    Call the Columbia Restaurant private dining department at 813.248.4961 and specify Casa Santo Stefano.
OpenTable
  • About Us
  • Blog
  • Careers
  • Press
More
Businesses
  • Restaurant reservation software
  • Industry insights
  • Hospitality resources
  • Marketing resources
  • Operation resources
  • How to open a restaurant
  • For restaurants
  • For restaurant groups
Join us on
  • Privacy Policy
  • Terms of Use
  • Cookies and Interest-Based Ads
  • Do Not Sell or Share My Personal Information
  • Cookie Preferences
Copyright © 2025 OpenTable, Inc. 1 Montgomery St Ste 500, San Francisco CA 94104 - All rights reserved.
OpenTable is part of Booking Holdings, the world leader in online travel and related services.
Booking Logo
Priceline Logo
KAYAK Logo
Agoda Logo
OpenTable Logo