144 Best Southern American Restaurants In Mission Hills

A photo of Old Town Tequila Factory Restaurant & Cantina restaurant

1. Old Town Tequila Factory Restaurant & Cantina

4.0

Excellent(1159)

Price: Moderate

• Southern american • Old Town

Booked 3 times today

Old Town Tequila Factory Restaurant & Cantina is an exceptional spot for authentic American cuisine, offering a delightful experience in the heart of San Diego’s historic Old Town. Diners rave about the "great service" and "fantastic views," making it an ideal destination for both locals and visitors. The rooftop setting adds a unique charm, perfect for a sunset dinner. The Sunday Champagne brunch is a standout, described as "excellent" with "lots to choose from." Whether you're celebrating a special occasion or enjoying a casual meal, the "impeccable service" and delicious food ensure a memorable dining experience.

A photo of Casa De Freds, Tacos y Tequila restaurant

2. Casa De Freds, Tacos y Tequila

4.7

Exceptional(328)

Price: Moderate

• Southern american • Old Town

Booked 4 times today

Casa De Freds, Tacos y Tequila, nestled in the heart of Old Town San Diego, has been the go-to spot for authentic Tex-Mex cuisine since 2001. This vibrant restaurant enchants diners with its "amazing tacos and appetizers" and "outstanding service." What truly sets Casa De Freds apart is its dedication to "quality food" made from fresh, high-quality ingredients, ensuring every bite is bursting with Baja-infused flavors. Guests rave about the "pure pleasure" of dining in their dog-friendly outdoor patio, making it a delightful experience for all. Whether you're a local or just visiting, Casa De Freds promises a festive and flavorful Tex-Mex feast!

3. Starlite

4.7

Exceptional(165)

Price: Expensive

• Southern american • Mission Hills

Booked 98 times today

Starlite: A timeless San Diego icon with a fresh future, helmed by Chef Ted Smith.Please note: Our establishment is 21+

4. Herb & Wood

4.7

Exceptional(6702)

Price: Expensive

• Southern american • Little Italy

Booked 53 times today

Herb & Wood in San Diego's vibrant Little Italy is a shining example of exquisite American cuisine. Celebrated Chef Brian Malarkey crafts a menu that elevates rustic, wood-fired dishes, blending Mediterranean flair with California's commitment to seasonality and sustainability. Diners rave about the "incredible dinner" experience, showcasing "amazing, flavorful food" and "outstanding service." The ambiance is described as "beautiful" and "welcoming," making every visit memorable. Signature dishes like the pork belly and filet mignon are praised for their exceptional taste. Whether you're celebrating a special occasion or enjoying a night out, Herb & Wood promises a "truly memorable culinary experience."

A photo of The Henry - Coronado restaurant

5. The Henry - Coronado

4.8

Exceptional(2745)

Price: Moderate

• Southern american • Coronado

Booked 136 times today

The Henry - Coronado is a standout destination for exquisite Cocktail Bar cuisine, offering a vibrant and lively atmosphere that feels like a second home. Situated in the heart of Coronado, it features an inviting bar where "creative cocktails are crafted to perfection," ensuring a delightful experience with every visit. Patrons rave about the "outstanding service" and "lively vibe," making it an ideal spot for social gatherings or unwinding after a long day. Whether you're enjoying a holiday drink or a classic concoction, the bar at The Henry ensures a memorable and authentic cocktail experience that keeps guests coming back for more.

6. Kettner Exchange

4.7

Exceptional(1470)

Price: Expensive

• Southern american • Little Italy

Booked 37 times today

Kettner Exchange in Little Italy, San Diego, offers an exceptional Asian fusion experience that is both inventive and authentic. Executive Chef Brian Redzikowski’s creations have earned the restaurant a coveted spot on the Michelin Guide's Bib Gourmand list since 2019, showcasing high-quality meals at accessible prices. Diners rave about the "spicy garlic noodles" and "juicy cheeseburger special," underscoring the delightful fusion of flavors. The rooftop patio with stunning harbor views enhances the dining ambiance, making it perfect for any occasion. Guests frequently praise the "stellar service" and "amazing cocktails," solidifying Kettner Exchange as a must-visit destination for Asian cuisine enthusiasts.

A photo of Ironside Fish & Oyster restaurant

7. Ironside Fish & Oyster

4.6

Exceptional(4680)

Price: Moderate

• Southern american • Little Italy

Booked 104 times today

Ironside Fish & Oyster in San Diego's Little Italy is a quintessential hotspot for authentic American cuisine, seamlessly blending traditional and contemporary flavors. This gem pays homage to its roots in the fishing industry with a mouthwatering menu that features renowned dishes such as the lobster roll and clam chowder, praised for being “chock full of clams.” The vibrant atmosphere and top-notch service are frequently highlighted in reviews, with one diner noting the “excellent experience, food, and ambience.” With a stellar raw bar and an enticing happy hour, Ironside promises a “delightful experience” that diners find irresistible.

A photo of Great Maple San Diego restaurant

8. Great Maple San Diego

4.8

Exceptional(4524)

Price: Moderate

• Southern american • Hillcrest

Booked 49 times today

Great Maple San Diego, nestled in the vibrant neighborhood of Hillcrest, is a beacon of excellence in Contemporary American cuisine. This modern eatery is celebrated for its "outstanding" food and "exceptional" service, making it a favorite destination for brunch, lunch, and dinner. Diners rave about the delightful maple bacon donuts and "delectable" brisket hash, highlighting the creative use of fresh, local ingredients. Reviewers consistently praise the "huge portions" and "fantastic flavors," ensuring no one leaves hungry. With its inviting atmosphere and "friendly" staff, Great Maple offers a truly authentic and memorable dining experience that captures the essence of Contemporary American cuisine.

A photo of Farmer's Bottega Restaurant restaurant

9. Farmer's Bottega Restaurant

4.8

Exceptional(1671)

Price: Moderate

• Southern american • Mission Hills

Booked 16 times today

Farmer's Bottega in Mission Hills, San Diego, offers an exquisite French culinary experience that effortlessly combines authenticity with farm-to-table freshness. Diners rave about the "wonderful dining experience," highlighting the chef’s dedication to using locally sourced ingredients that bring the vibrant flavors of French cuisine to life. Whether indulging in the tender duck gnocchi or savoring the perfectly prepared Cacio E Pepe, each dish is a celebration of French culinary artistry. The charming ambiance, complemented by a beautiful outdoor patio, creates the ideal setting for an unforgettable meal. With exceptional service and a menu brimming with delightful options, this restaurant truly stands out as a neighborhood gem.

A photo of Rustic Root - Gaslamp restaurant

10. Rustic Root - Gaslamp

4.4

Awesome(1419)

Price: Expensive

• Southern american • Downtown

Booked 35 times today

Rustic Root showcases our take on New American Comfort food with a California twist. Classic dishes are rooted in tradition, including regional dishes from around the country. All reimagined with fresh and local ingredients and our Chef’s modern flair. Our Signature drink menus offer our take on timeless classic cocktails as well as Rustic Root originals using creative spirits and the freshest ingredients. Join us in our street-level dining room for dinner nightly or our award-winning weekend brunch. Our rooftop lounge is an excellent place to grab drinks & a bite with friends, enjoying the San Diego weather and our unique location in the heart of the Gaslamp Quarter. Close to the San Diego Convention Center, we're a favorite for locals and out of town tourists alike.

Best Southern American Restaurants in Mission Hills

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144 restaurants available nearby

1. Old Town Tequila Factory Restaurant & Cantina

2. Casa De Freds, Tacos y Tequila

3. Starlite

4. Herb & Wood

5. The Henry - Coronado

6. Kettner Exchange

7. Ironside Fish & Oyster

8. Great Maple San Diego

9. Farmer's Bottega Restaurant

10. Rustic Root - Gaslamp

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