Best Regional Mexican Restaurants in Serra Mesa

Perfection at every level Celeste treated us amazing and cared for me and my family

We loved the food, the only bad thing is that we waited more than an hour for the food to arrive to the table. They had a baby-shower going on, the bad thing is that we couldn’t find our server to order a drink or any update on our order, we were very confused. My friend had to rush eating her meal and request a to-go box leaving without finishing her meal. They nicely send us a flan but still not a good experience for all of us.

If you’re looking for authentic, flavorful, and consistently delicious Mexican food in La Mesa, look no further than Mario’s de la Mesa. From the moment you walk in, you’re greeted with warm, friendly service that makes you feel like part of the family. The atmosphere is cozy, casual, and filled with the mouthwatering aroma of fresh, homemade dishes. Their carne asada burrito is hands-down one of the best in San Diego County — perfectly grilled, tender, and packed with flavor. The enchiladas are always spot on, smothered in rich, savory sauce, and their chile relleno is a must-try: crispy on the outside, soft and cheesy on the inside. The chips and salsa are fresh and addictive, and their margaritas are the perfect blend of tart and sweet. What really sets Mario’s apart is the genuine care they put into every plate and every guest experience. It’s no surprise this place has such a loyal local following. Whether you’re stopping by for a casual lunch, a family dinner, or celebrating with friends, Mario’s de la Mesa delivers every time. Highly, highly recommend — this gem is a La Mesa treasure!

Authentic food and incredible flavors! I hope this place blows up!