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Best Southwest American Restaurants in South San Antonio

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60 restaurants available nearby

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A photo of Domingo Restaurante restaurant
1. Domingo Restaurante
4.5
Awesome(963)
Price: Expensive
• Mexican • Downtown
Booked 85 times today
Join us in our open-air restaurant on the Historic San Antonio River Walk with a natural ambiance where curated contemporary art intersects with a historical setting. Domingo's menus offer the flavors of South Texas and an agave-forward beverage program celebrating the culture of San Antonio with modern culinary flair.
A photo of Bohanan's Prime Steaks and Seafood restaurant
2. Bohanan's Prime Steaks and Seafood
4.8
Exceptional(8447)
Price: Very Expensive
• Mexican • Downtown
Booked 33 times today
Bohanan's Prime Steaks and Seafood in downtown San Antonio elevates seafood dining to an art form. Known for its "succulent seafood flown in fresh daily," the restaurant ensures that each dish bursts with authentic, ocean-fresh flavors. Diners rave about the "macadamia encrusted red snapper" and "outstanding salmon" that epitomize the exquisite quality of their seafood offerings. The AAA Four Diamond-rated restaurant pairs its seafood with impeccable service, creating an extraordinary dining experience. Located in a historic building near the River Walk, Bohanan's is a must-visit for seafood lovers seeking a memorable meal in a stunning, elegant setting.
A photo of Brenner's on the River Walk restaurant
3. Brenner's on the River Walk
4.6
Exceptional(433)
Price: Moderate
• Mexican • Downtown
Booked 23 times today
Brenner's on the River Walk in San Antonio offers a quintessential American dining experience that beautifully marries tradition with elegance. With roots tracing back to 1936, Brenner's is renowned for its commitment to authentic American flavors and exceptional quality. Guests rave about its "phenomenal" dishes, especially the American Wagyu and the delectable bacon-wrapped shrimp. The restaurant's picturesque setting along the River Walk adds to its charm, providing breathtaking views from both indoor and balcony seating. Patrons consistently highlight the "excellent" service, noting that it enhances their dining experience, making Brenner's a must-visit for anyone seeking top-tier American cuisine.
A photo of Supper restaurant
4. Supper
4.7
Exceptional(3262)
Price: Expensive
• Mexican • Downtown
Booked 45 times today
Supper, nestled in the heart of Downtown San Antonio, is a shining beacon of exquisite American cuisine. Housed within the historic Hotel Emma, this restaurant seamlessly marries South Texas hospitality with a modern flair. Diners frequently rave about the "sensational" food and "wonderful atmosphere," making it a favored spot for both locals and visitors alike. Whether enjoying a brunch with friends or a romantic dinner overlooking the river, Supper offers a diverse menu that guarantees satisfaction. The "divine" dishes and "attentive" service ensure that every meal is a memorable experience, solidifying Supper as a must-visit destination for authentic American dining.
A photo of Little Em's Oyster Bar restaurant
5. Little Em's Oyster Bar
4.5
Awesome(901)
Price: Expensive
• Mexican • Downtown
Booked 35 times today
Little Em's Oyster Bar in Downtown San Antonio serves up some of the finest American cuisine, with a focus on fresh seafood that truly sets it apart. The restaurant's oysters are a standout, often described as "super delicious & fresh," and they're expertly shucked to perfection. But the culinary delight doesn't stop there; their lobster rolls, celebrated as "always delicious," offer an authentic taste of the American Northeast. With a welcoming atmosphere and attentive service, Little Em's is hailed as a "cute little gem" and the "best fresh-oyster restaurant in San Antonio." It's the perfect spot for a memorable dining experience!
A photo of Biga on the Banks restaurant
6. Biga on the Banks
4.8
Exceptional(5869)
Price: Very Expensive
• Mexican • Downtown
Booked 26 times today
Biga on the Banks, located in the heart of Downtown San Antonio, offers an exceptional Dining Bar experience that truly elevates the culinary scene. Overlooking the scenic San Antonio River Walk, it boasts a modern yet inviting ambiance that draws both locals and visitors alike. The menu, crafted by the renowned Bruce Auden, features exquisite dishes like Mahi Mahi and Hill Country Venison. Diners rave about the “fantastic food and great service,” while the eclectic wine list and craft cocktails provide the perfect accompaniment to any meal. With accolades for its consistently high-quality offerings, Biga on the Banks is undoubtedly a "must-go" for anyone seeking an unforgettable dining adventure.
A photo of Southerleigh Fine Food & Brewery restaurant
7. Southerleigh Fine Food & Brewery
4.8
Exceptional(3192)
Price: Moderate
• Mexican • Downtown
Booked 69 times today
Southerleigh Fine Food & Brewery in Downtown San Antonio stands as a beacon of authentic American cuisine, blending coastal classics with comforting Southern flavors. Helmed by the talented Chef Jeff Balfour, the restaurant offers a dynamic, seasonally shifting menu that showcases his innovative craftsmanship. Diners rave about the "fantastic food," with standout dishes like the perfectly fried Snapper Throats and "best fried chicken in San Antonio." The brewery enhances the dining experience with its custom-crafted beers. Guests consistently praise the "outstanding service" and inviting atmosphere, making it a must-visit for anyone seeking a true taste of American culinary excellence.
A photo of Bliss Restaurant restaurant
8. Bliss Restaurant
4.9
Exceptional(5099)
Price: Very Expensive
• Mexican • Downtown
Booked 43 times today
Bliss is consistently among San Antonio’s best restaurants in terms of quality, service and atmosphere. Bliss is located just blocks away from downtown San Antonio in the burgeoning Southtown area. Our mission is to express excellence in the most inclusive, genuine and hospitable way. Bliss serves contemporary American cuisine. Our menu changes frequently with an emphasis on what is seasonal and creative over what is predictable and familiar. Our goal is to create a relaxed yet elegant dining experience in a genuine and comfortable environment.
A photo of Boiler House at Pearl restaurant
9. Boiler House at Pearl
4.7
Exceptional(2166)
Price: Expensive
• Mexican • Downtown
Booked 52 times today
Boiler House at Pearl is a standout destination for authentic American cuisine in Downtown San Antonio. Nestled in the historic Pearl Brewery complex along the vibrant River Walk, this restaurant offers a unique dining experience with a focus on "Texas ranch-style" dishes that capture the essence of American flavors. Led by Executive Chef Alberto "Beto" Gutierrez, the menu boasts high-quality, locally-sourced grilled items that are consistently praised by diners. Reviewers rave about the "amazing experience" and "delicious food," with standout dishes like the perfectly cooked porterhouse steak and the inventive shrimp fritto misto. The warm, welcoming atmosphere and attentive service make Boiler House a must-visit.
A photo of Landry's Seafood House - San Antonio restaurant
10. Landry's Seafood House - San Antonio
4.4
Awesome(2682)
Price: Moderate
• Mexican • Downtown
Booked 32 times today
Landry's Seafood House in Downtown San Antonio offers an authentic taste of American cuisine with a Gulf Coast flair. Known for its "phenomenal" seafood dishes, this restaurant excels in delivering both quality and flavor, making it a standout destination for American dining. Guests rave about the "exceptional" service, with attentive staff like Ernesto and Crystal enhancing the dining experience. Nestled along the Riverwalk, the ambiance adds to the allure, providing a perfect setting for celebrations. Whether indulging in the melt-in-your-mouth bass or the delectable butter cake, diners leave with a "great experience" that keeps them coming back for more.
‘About the restaurant’ descriptions have been generated using an artificial intelligence model comprised of OpenTable proprietary data that has not been independently verified by OpenTable. The content is presented as-is, for informational purposes only.

See what locals rave about

From verified diners like you
From verified diners like you
  • Tiffany
    San Antonio •4 reviews
    5.0
    Dined 4 days ago
    Food was delicious! New strawberry salad that comes with the asados course was DELICIOUS. Thank you to Pace and others that helped throughout our night! Outstanding service and veryyyyy amazing food!!
    More info
    MezquitePrice: Moderate• Northern Mexican• Downtown
    •
    4.4
  • Cari
    Houston •10 reviews
    4.0
    Dined 5 days ago
    Food was great! Loved the beef skewers and fajitas. Service was good. Restaurant could have been a little cleaner and there was a bird flying around in the restaurant that needed to be removed.
    More info
    ÁcenarPrice: Moderate• Contemporary Mexican• Downtown
    •
    4.4
  • Ana
    San Antonio •1 review
    4.0
    Dined 6 days ago
    The food was great and I loved everything except for the service. Our waiter was not attentive at all. I made a reservation indicating that we were celebrating an 88th birthday, and it wasn’t even acknowledged.
    More info
    Domingo RestaurantePrice: Expensive• Mexican / Southwestern• Downtown
    •
    4.5
  • Joe
    San Antonio •1 review
    5.0
    Dined 7 days ago
    When my party first arrived the staff were very polite and friendly and when I had to inform them my party is bigger than what I had reserved they were very understanding and were quick to work on a solution for my party. Due to my party being higher than 8 people we did have to sit outside but that was no problem at all because they have fans that helped cool us off, and they also have water mist they can enable to further cool off guest. The food was fantastic and everything looked picture perfect, I plan on returning to try more!
    More info
    Alamo Biscuit Company & PanaderiaPrice: Moderate• Mexican / Southwestern• Downtown
    •
    4
  • NoelVIP
    San Antonio •67 reviews
    5.0
    Dined on Jun 3, 2025
    Top quality TexMex as always. Only service quibble: we normally receive a little cup of melted butter with the grilled shrimp. No big deal to me, but my husband enjoys it. Will make a point to ask for it next time if it doesn't appear. Otherwise great as usual.
    More info
    Dos Rios Mexican Bar & GrillPrice: Moderate• Mexican• New Braunfels
    •
    4.8

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