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Best American Restaurants in South Side East

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51 restaurants available nearby

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A photo of Domingo Restaurante restaurant
1. Domingo Restaurante
4.5
Awesome(963)
Price: Expensive
• American • Downtown
Booked 85 times today
Join us in our open-air restaurant on the Historic San Antonio River Walk with a natural ambiance where curated contemporary art intersects with a historical setting. Domingo's menus offer the flavors of South Texas and an agave-forward beverage program celebrating the culture of San Antonio with modern culinary flair.
A photo of Brenner's on the River Walk restaurant
2. Brenner's on the River Walk
4.7
Exceptional(434)
Price: Moderate
• American • Downtown
Booked 23 times today
Brenner's on the River Walk in San Antonio offers a quintessential American dining experience that beautifully marries tradition with elegance. With roots tracing back to 1936, Brenner's is renowned for its commitment to authentic American flavors and exceptional quality. Guests rave about its "phenomenal" dishes, especially the American Wagyu and the delectable bacon-wrapped shrimp. The restaurant's picturesque setting along the River Walk adds to its charm, providing breathtaking views from both indoor and balcony seating. Patrons consistently highlight the "excellent" service, noting that it enhances their dining experience, making Brenner's a must-visit for anyone seeking top-tier American cuisine.
A photo of Bohanan's Prime Steaks and Seafood restaurant
3. Bohanan's Prime Steaks and Seafood
4.8
Exceptional(8453)
Price: Very Expensive
• American • Downtown
Booked 23 times today
Bohanan's Prime Steaks and Seafood in downtown San Antonio elevates seafood dining to an art form. Known for its "succulent seafood flown in fresh daily," the restaurant ensures that each dish bursts with authentic, ocean-fresh flavors. Diners rave about the "macadamia encrusted red snapper" and "outstanding salmon" that epitomize the exquisite quality of their seafood offerings. The AAA Four Diamond-rated restaurant pairs its seafood with impeccable service, creating an extraordinary dining experience. Located in a historic building near the River Walk, Bohanan's is a must-visit for seafood lovers seeking a memorable meal in a stunning, elegant setting.
A photo of Bliss Restaurant restaurant
4. Bliss Restaurant
4.9
Exceptional(5099)
Price: Very Expensive
• American • Downtown
Booked 30 times today
Bliss is consistently among San Antonio’s best restaurants in terms of quality, service and atmosphere. Bliss is located just blocks away from downtown San Antonio in the burgeoning Southtown area. Our mission is to express excellence in the most inclusive, genuine and hospitable way. Bliss serves contemporary American cuisine. Our menu changes frequently with an emphasis on what is seasonal and creative over what is predictable and familiar. Our goal is to create a relaxed yet elegant dining experience in a genuine and comfortable environment.
A photo of Biga on the Banks restaurant
5. Biga on the Banks
4.8
Exceptional(5871)
Price: Very Expensive
• American • Downtown
Booked 25 times today
Biga on the Banks, located in the heart of Downtown San Antonio, offers an exceptional Dining Bar experience that truly elevates the culinary scene. Overlooking the scenic San Antonio River Walk, it boasts a modern yet inviting ambiance that draws both locals and visitors alike. The menu, crafted by the renowned Bruce Auden, features exquisite dishes like Mahi Mahi and Hill Country Venison. Diners rave about the “fantastic food and great service,” while the eclectic wine list and craft cocktails provide the perfect accompaniment to any meal. With accolades for its consistently high-quality offerings, Biga on the Banks is undoubtedly a "must-go" for anyone seeking an unforgettable dining adventure.
A photo of 1 Watson restaurant
6. 1 Watson
4.4
Awesome(536)
Price: Moderate
• American • Downtown
Booked 22 times today
Escape the ordinary at 1 Watson, a rooftop oasis 15 floors above San Antonio. Enjoy stunning views of the River Walk, Main Plaza, and San Fernando Cathedral while indulging in modern Southwestern cuisine and expertly crafted cocktails.Savor Texas-inspired dishes like Smoked Brisket Tacos or The Chicken Tinga Salad, each reflecting the region's culinary heritage with a contemporary twist.Quench your thirst with a curated selection of craft cocktails. Enjoy refreshing margaritas, the smoky notes of Texas-made bourbon, or vibrant handcrafted gin and tonics. Each drink is designed to enhance the breathtaking views and delicious food.Step into a sophisticated ambiance with industrial-chic design and modern Texas touches. Relax in plush seating and bask in the warm glow of the fire, making 1 Watson the perfect destination for an unforgettable dining experience.**Please note after 9:00PM we are 21+, no reservations will be honored after this time to any individuals under 21.
A photo of Four Brothers Southern Provisions restaurant
7. Four Brothers Southern Provisions
4.6
Exceptional(468)
Price: Expensive
• American • Downtown
Booked 18 times today
Four Brothers Southern Provisions in Downtown San Antonio offers a delightful journey into Contemporary Latin cuisine, seamlessly blending modern South Texas flavors with Latin and French influences. Diners rave about the standout dishes like the "Texas-sized cornbread" and "shrimp and grits," which are lauded as must-tries. The vibrant atmosphere and impeccable service enhance the dining experience, with patrons frequently praising the staff's attentiveness. One reviewer excitedly noted, "The food was phenomenal," while another declared, "Amazing food! Great service!" The restaurant's beautiful Riverwalk location adds to its charm, making it a perfect spot to enjoy authentic and innovative Latin-inspired dishes.
A photo of Little Em's Oyster Bar restaurant
8. Little Em's Oyster Bar
4.5
Awesome(902)
Price: Expensive
• American • Downtown
Booked 36 times today
Little Em's Oyster Bar in Downtown San Antonio serves up some of the finest American cuisine, with a focus on fresh seafood that truly sets it apart. The restaurant's oysters are a standout, often described as "super delicious & fresh," and they're expertly shucked to perfection. But the culinary delight doesn't stop there; their lobster rolls, celebrated as "always delicious," offer an authentic taste of the American Northeast. With a welcoming atmosphere and attentive service, Little Em's is hailed as a "cute little gem" and the "best fresh-oyster restaurant in San Antonio." It's the perfect spot for a memorable dining experience!
A photo of Landry's Seafood House - San Antonio restaurant
9. Landry's Seafood House - San Antonio
4.4
Awesome(2683)
Price: Moderate
• American • Downtown
Booked 31 times today
Landry's Seafood House in Downtown San Antonio offers an authentic taste of American cuisine with a Gulf Coast flair. Known for its "phenomenal" seafood dishes, this restaurant excels in delivering both quality and flavor, making it a standout destination for American dining. Guests rave about the "exceptional" service, with attentive staff like Ernesto and Crystal enhancing the dining experience. Nestled along the Riverwalk, the ambiance adds to the allure, providing a perfect setting for celebrations. Whether indulging in the melt-in-your-mouth bass or the delectable butter cake, diners leave with a "great experience" that keeps them coming back for more.
A photo of Ácenar restaurant
10. Ácenar
4.4
Awesome(2657)
Price: Moderate
• American • Downtown
Booked 25 times today
Ácenar in Downtown San Antonio is a true gem for lovers of Fusion and Eclectic cuisine, seamlessly blending contemporary Mexican flavors with Texas regional influences. This innovative culinary hotspot is celebrated for its "culinary explosion of bold Latin-infused flavors," as described by delighted diners. Executive Chef Richard Sánchez crafts dishes that offer a modern twist on traditional favorites, such as seafood enchiladas and sizzling parrilladas, which have been described as "exceptional" and "absolutely delicious." With its hip design and vibrant atmosphere, Ácenar provides a memorable dining experience that stands out on the River Walk, making it a must-visit destination.
‘About the restaurant’ descriptions have been generated using an artificial intelligence model comprised of OpenTable proprietary data that has not been independently verified by OpenTable. The content is presented as-is, for informational purposes only.

See what locals rave about

From verified diners like you
From verified diners like you
  • Chris
    Detroit / Eastern Michigan •5 reviews
    5.0
    Dined 2 days ago
    Great place. Service was great and food was incredible. I had the New York Strip and it was one of the best streaks I've ever had. The Mac and cheese was awesome too.
    More info
    Bohanan's Prime Steaks and SeafoodPrice: Very Expensive• Steakhouse• Downtown
    •
    4.8
  • Wesley
    San Antonio •15 reviews
    5.0
    Dined 2 days ago
    Biga on the Banks is on our very-short list of favorites for special events. This time, my wife was treating me to an early Father's Day celebration. The food was delicious. I started with the spinach salad; my wife had the roasted beet and goat cheese. For entrees, we chose the wild game (antelope and quail) and tenderloin. The medium rare preparation was perfect! Unable to make a decision from among the excellent choices for dessert, we opted for the Biga sampler and asked for a small scoop of vanilla bean on the side. A perfect end to the meal! Rosemary, our server, was great! She was able to strike that difficult balance of being sufficiently attentive but leaving us to converse uninterrupted. Rosemary had helpful suggestions for wine pairings (a zinfandel for the wild game and a syrah for the tenderloin). All in all, a fine evening of fine dining on the river!
    More info
    Biga on the BanksPrice: Very Expensive• Contemporary American• Downtown
    •
    4.8
  • Roger
    San Antonio •4 reviews
    5.0
    Dined 2 days ago
    Simply amazing as usual...nailed every single detail of service and food. Family was amazed at all the flavors and complexity of all the dishes. Butter Cake was the cherry on top!
    More info
    Bliss RestaurantPrice: Very Expensive• Contemporary American• Downtown
    •
    4.9
  • Ana
    San Antonio •1 review
    4.0
    Dined 7 days ago
    The food was great and I loved everything except for the service. Our waiter was not attentive at all. I made a reservation indicating that we were celebrating an 88th birthday, and it wasn’t even acknowledged.
    More info
    Domingo RestaurantePrice: Expensive• Mexican / Southwestern• Downtown
    •
    4.5
  • OpenTable Diner
    Texas Panhandle •3 reviews
    5.0
    Dined on Jun 5, 2025
    Beautiful food, great service. Even sat us before our reservation!
    More info
    Brenner's on the River WalkPrice: Moderate• Steakhouse• Downtown
    •
    4.7

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