Best American Restaurants in Medical Center

Price: Moderate (94)Price: Expensive (46)Price: Very Expensive (28)

78 restaurants available nearby

A photo of Alamo Biscuit Company & Panaderia restaurant

1. Alamo Biscuit Company & Panaderia

4.7

Exceptional(5)

Price: Moderate

• American • Northwest

Booked 4 times today

*For reservations over 12, please contact us directly at 210-204-8520. *On the weekend, we only take reservations for parties of 6-12, for questions please contact us directly 210-204-8520.Great hospitality is an extension of great service, taking it to another level. Here at Alamo Biscuit Co., hospitality is a great dining experience that goes far beyond great food and great service. A truly great dining experience is when our guest’s needs are anticipated and met for them, resulting in 100% satisfaction. Our goal is to always strive to make every moment memorable.

A photo of Dave & Buster's - San Antonio (Balcones Heights) restaurant

2. Dave & Buster's - San Antonio (Balcones Heights)

3.9

Excellent(97)

Price: Moderate

• American • Medical Center

Booked 49 times today

Dave & Buster's - San Antonio (Balcones Heights) stands as a quintessential example of good American cuisine. This venue has received rave reviews for its great food, excellent service, and accommodating atmosphere. Patrons have praised the restaurant as a "great place to eat and play and celebrate any occasion," while others have noted the "great experience and great service" they enjoyed during their visits. The food and service, described as "amazing," "satisfying," and "very good," contribute to the venue's reputation as a family-friendly destination. From last-minute reservations to large party accommodations, reviews highlight the easy and efficient service, making Dave & Buster's a go-to place to experience American cuisine.

A photo of 54th Street Restaurant & Drafthouse - The Colonnade restaurant

3. 54th Street Restaurant & Drafthouse - The Colonnade

(0)

Price: Moderate

• American • Medical Center

54th Street was founded in Kansas City, MO by Thomas E. Norsworthy in 1989. He envisioned a place that would accommodate a consistently crowded dining room as well as a lively bar crowd, while offering the quality food and drinks that exceed national chain competitors. At 54th Street, we believe that great food starts with fresh produce, high quality meats and ingredients and meals prepared from scratch. With our amazing range of scratch prepared menu items, we truly have something for everyone. The Five-Four promise is to forever uphold our tradition of serving generous portions of housemade food and drink at an honest price. 54th Street welcomes you for all occasions. Drop in for Happy Hour with friends, celebrate a special occasion, enjoy a family night out or fly solo! Ultimately, it’s your time. Join us, experience 54 and share the 54 experience with others.

4. Kona Grill - North Star

4.2

Awesome(575)

Price: Moderate

• American • North San Antonio

Booked 3 times today

Kona Grill - North Star serves up a fantastic experience of American cuisine, with many reviewers applauding the excellence of its food, service, and atmosphere. The menu is a pleasant mix of creativity and originality, with significant Asian influences. Reviewers were particularly intrigued by the Macadamia Nut French Toast, the Sunset roll, and the prime rib with lobster. The macadamia pie, similar to a pecan pie but decidedly better, was praised as a perfect ending to the meal. Customers also appreciated the attentive service, with people like one Greek waiter, making this a dining experience to remember. The restaurant doesn't shy away from embracing American brunch culture, offering dishes such as the Rocky Mountain Omelet and Eggs Benedict. Despite the occasional remark on high prices, the consensus is that Kona Grill - North Star provides a worthwhile dining experience.

A photo of Rock & Brews - San Antonio restaurant

5. Rock & Brews - San Antonio

4.3

Awesome(7)

Price: Moderate

• American • North Central

Booked 10 times today

We have it all! American food, craft beers, signature cocktails, large parties and private dining space, live music, catering, live sports, dog-friendly patios, and more! Rock your taste buds with our American inspired menu boasting creative spins on the standards. Our menu items are prepared from scratch using fresh ingredients from the local community. Wash down our culinary creations with one of our 48+ craft beers on tap from local, national, and international breweries or check out our signature cocktails and extensive bourbon and tequila selections! The restaurant can accommodate sports fanatics and large parties of any size (including family and corporate gatherings, youth sports teams, and rehearsal dinners) in our sizable dining room or on our private patios. The restaurant also features live music, weekday lunch specials, a dog-friendly outdoor patio (ask to see our dog menu), and brunch on the weekends.

A photo of Pinstack - San Antonio - Park North restaurant

6. Pinstack - San Antonio - Park North

3.7

Very Good(24)

Price: Moderate

• American • Victoria

Booked 4 times today

Pinstack - San Antonio is a top-notch locale for American cuisine. The restaurant stands out not only for its outstanding service, but also for its exquisite dishes, as numerous reviews testify. One customer enthusiastically praised the sriracha wings as "absolutely delicious", indicating the establishment's commitment to perfecting American favorites. Another commended the "outstanding" staff, a key factor in creating a memorable dining experience. From the enticing food offerings to the exceptional service, Pinstack - San Antonio certainly enhances the reputation of American cuisine.

A photo of Perry's Steakhouse & Grille - San Antonio restaurant

7. Perry's Steakhouse & Grille - San Antonio

4.8

Exceptional(9094)

Price: Expensive

• American • La Cantera

Booked 48 times today

Located at La Cantera Parkway in San Antonio, Perry's Steakhouse & Grille has made a name for itself with its premium steakhouse cuisine. Patrons continually praise the excellent service, exceptional food, and the thoughtful attention to detail. The restaurant is particularly acclaimed for its juicy pork chop, succulent New York strip flight, and perfectly cooked filets. The ambiance adds to the overall dining experience, making Perry's a popular place for celebrations. One reviewer said, "Food is amazing, great experience, pork chop is my favorite so far and the truffle wedges are a MUST when you go! By far my favorite steakhouse in San Antonio!" With consistently high praise, Perry's offers a truly satisfying steakhouse experience.

A photo of Chart House Restaurant - Tower of the Americas restaurant

8. Chart House Restaurant - Tower of the Americas

4.5

Awesome(16254)

Price: Moderate

• American • Downtown

Booked 142 times today

The Chart House Restaurant - Tower of the Americas in San Antonio is a favorite for its excellent seafood cuisine. Highly recommended by several reviewers, the restaurant offers a variety of fresh seafood dishes, including lobster, shrimp, and crab, all masterfully cooked. One patron shared that "the seafood appetizers and main dish selections had a wide variety." The freshness of the seafood is appreciated, as another customer highlighted that the restaurant gets its seafood within 12 hours of it being caught. The experience extends beyond the food, with the ambiance and service receiving accolades as well. Reviewers described the view as 'unforgettable' with many commending the outstanding service. Though, some noted that the space is quite cramped, they found the overall experience well worth it, making the Chart House a top choice for seafood lovers.

A photo of Ida Claire - San Antonio restaurant

9. Ida Claire - San Antonio

4.6

Exceptional(2405)

Price: Moderate

• American • Alamo Heights

Booked 105 times today

Ida Claire is a funky, southern influenced restaurant & bar open for breakfast, lunch, and dinner. The food is notched up southern but has influences from different regions. You’ll most likely see dishes you’ve heard of before but with little twists here and there. Our sandwiches will be served on biscuits & we’ll have chicken & waffles on every menu. Brunch is obviously southern & will be a big part of what we do. The drinks are takes on classics like the Mint Julep but revved up & including a lot of house made ingredients.

10. Signature

4.9

Exceptional(2544)

Price: Very Expensive

• American • La Cantera

Booked 31 times today

Signature, located in the heart of San Antonio, delivers an exceptional dining experience with its superb American cuisine. The restaurant has fast become one of San Antonio's best, applauded not only for its impressive food but also for its excellent service. According to various reviews, Signature has gained popularity due to its delicious food, inviting ambiance, and exemplary service. Dishes like Golden Beets with goat cheese, Summer Truffle Risotto, and Chilean Sea Bass are some of the favorites, drawing in diners again and again. Moreover, feedback highlights the expertise of the staff, the delicious cocktails, and the overall dining experience, with one diner even preferring it over a memorable meal in France.

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