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Diners' Choice: Innovative restaurants in Key West / Florida Keys

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OpenTable
Updated May 05, 2025

Looking for the best restaurants that are fit for foodies in Key West / Florida Keys? You’re in the right place. Each month, OpenTable analyzes nearly 2 million global diner reviews from the past four months. We sort the results by location and category to help you discover new favorite restaurants. It's a great partnership: you reserve, eat, and review. We listen...and deliver the results for all to benefit. Enjoy!


A photo of Red Shoe Island Bistro restaurant
4.9
4.9 (1538)
$31 to $50
American
Key West
About the restaurant
Key West seafood restaurant in the heart of old town on Petronia. The menu is kept small so that everything is nice and fresh for you. Yellowtail snapper, fish of the day, Key West pink shrimp, and seafood medley highlight the menu.
Deviled Eggs topped with Scallops, Shrimp Mango Toast and Crispy Pork Belly Croustinis tantalize the pallet. Beef stroganoff made with certified black angus beef is a favorite.

Relaxing, unpretentious, and romantic.
Seating is very limited. We offer a 6 pm and an 8 pm seating.
24 Hour Cancellation window.
For the consideration of our guests, we do not accept parties over the size of six (6), without the permission for the owners.
20% gratuity added to parties of six (6) or more.
BEER AND WINE AVAILABLE ONLY.
No Children's menu available.

Top review
BeverlyVIP
Dined 5 days ago
Ambience, food quality and service were all excellent!
A photo of Santiago's Bodega Key West restaurant
4.8
4.8 (2421)
$31 to $50
Tapas / Small Plates
Key West
About the restaurant
Since 2003, Santiago's Bodega Key West in Bahama Village has been serving globally inspired small plates in a vibrant, inviting atmosphere. We offer indoor and outdoor seating. For parties of 6 or more, please call the restaurant to reserve. We are a neighborhood gem. Reservations are highly recommended.

Open daily from 11:00am-10:00pm. We offer Happy Hour seven days a week from 3:00pm-6:00pm featuring half-priced sangria, wine by the glass, draft beer, and select $7 tapa specials. We look forward to welcoming you!

Top review
Jenna
Dined 2 days ago
My mom and I had dinner at Santiago’s Bodega on the recommendation of a friend who used to live in Key West, and it did not disappoint. The ambiance was cozy and vibrant, and as two big fans of tapas (one vegetarian, one no fish), we were thrilled with the variety of options. We shared the patatas bravas (best I’ve had outside of Madrid!), avocado and pear salad, saganaki, and croquetas—each dish was absolutely divine. Our server, Chris, was kind, attentive, and made the experience even better. We also loved the red sangria—super refreshing and perfectly balanced. The only thing we didn’t love as much was the cheese selection on the charcuterie board. The truffle pecorino had a very soft texture and strong blue flavor, and the pepper cheddar packed an intense spicy punch. It was still fun to try, but a milder option like manchego would’ve been a welcome addition. Despite that, I’d go back in a heartbeat—if I can snag another reservation before we leave, I absolutely will. Highly recommend for anyone looking for amazing tapas in Key West!
A photo of Cafe Marquesa restaurant
4.8
4.8 (3110)
$50 and over
Contemporary American
Key West
About the restaurant
A premier choice for fine dining in Old Town Key West.

Like Charleston and other great ports of the South, Key West offers endless inspiration for chefs. Once a stop on trade routes to the Caribbean, the island developed a signature cuisine that’s practically an open book for flavors. Pair this with the bounty from two bodies of water and the signatures of great chefs who have dedicated time here and a compelling cuisine emerges.

From its inception, Café Marquesa has led the way in expressing a unique, coastal cuisine. Our kitchen combines the finest seafood, meats, and produce with classic preparations and creativity. We offer fine dining with an authentic, homespun essence, like freshly baked bread and desserts made daily in-house. A local favorite for special occasions, and a place to settle into and savor. Every dinner layers memory upon memory. Join us and find yours.


Top review
PeterVIP
Dined 7 days ago
Really wonderful food, great atmosphere, wonderful service. The grouper was superb, as was everything else
A photo of Seven Fish restaurant
4.8
4.8 (3177)
$31 to $50
Seafood
Key West
About the restaurant
Simple. Good. Food.

From humble beginnings over 20 years ago, Seven Fish has earned its place as a Key West Classic.

Serving the freshest local fish in a casual, contemporary bistro setting, it is the perfect finish to your Key West day.

Unpretentious dishes, with a commitment to only the finest ingredients, and made from scratch every day, it is the meal you don’t want to end.

Try our house specialty, Thai Curry Snapper, or any of our fresh fish dishes, or maybe the Banana Chicken or even the locals’ favorite, 7 Fish Meatloaf. There is something for everyone, lovingly prepared to exceed your expectations, including our specialty drinks and inspiring wine menu. Be sure to save room for one of our home made, classic desserts.

You will love our beautiful new building, enjoy our warm, friendly staff and come back again and again for the remarkable food.

Top review
Amy
Dined 3 days ago
What a lovely dining experience! Interesting menu options, fantastic food & drinks! Wait staff was was knowledgeable and personable. And gifted us a slice of Key Line pie to celebrate our anniversary! Top notch!
A photo of Little Pearl restaurant
4.8
4.8 (2945)
$50 and over
Seafood
Key West
About the restaurant

We are OPEN 6 nights a week with 3 seating times
Monday-Saturday 5pm/7pm/9pm
Offering Chef’s Tasting Menu only. Unfortunately, our regular menu is unavailable at this time. Follow our website, Facebook, or IG for most current menu offerings... or just give us a call!
Please contact the restaurant with ALL dietary restrictions 24 hours before reservation for us to accommodate.
Thank you for your support during these unprecedented times! Looking forward to seeing you again!

Nestled in the heart of Old Town and away from the bustling downtown streets of Key West, Florida, sits an excellent spot for fresh local catch and innovative cuisine with a tropical twist.
Reservations are recommended!! Please call us for parties larger than 4 people.

Top review
cliveVIP
Dined 6 days ago
A great little restaurant offering a lovely dinning experience.
A photo of Atlas Izakaya restaurant
4.8
4.8 (346)
$31 to $50
Japanese
Key West
About the restaurant
Atlas Izakaya is a chef-run restaurant focused on creating delicious, thought-provoking Japanese food. Meaning “stay-drink-place” in its native tongue, Izakaya is a word to describe the perfect spot to settle down with company as you dine together. Located in the heart of historic Key West steps from Duval Street, our restaurant provides a relaxed vibe to meet your palate. To live up to our name, we created a refined atmosphere that features an impressive open kitchen to complement the same great impression made by our menu. Complete with local seafood, sushi, fresh vegetable dishes, bao buns, dumplings, and much more, our offerings are the kind you’ll be craving in the weeks following your visit. If you’re in the mood for cozy comfort and whimsical Asian cuisine, join us at Atlas Izakaya.
305-998-4189

Top review
AlexVIP
Dined on May 13, 2025
Awesome experience from start to finish. Great food and great service. Wide variety of options and some incredible luxury ingredients. Take your time and enjoy. You can continue to order throughout the dining experience. This was our first time and we will be back.
A photo of Italian Food Company - Key Largo restaurant
4.7
4.7 (220)
$30 and under
Italian
Key Largo
About the restaurant
A slice of Italy in the Florida Keys! This approachable and genuine pizzeria/trattoria serves authentic Italian dishes in a warm and memorable atmosphere. Locals, families, couples, and groups flock to Italian Food Company for the food, service and attention to detail. Guests dine on imported, hand painted lava tables made by local artisans from the foothills of Mt. Etna, while overlooking our wine and beer garden. Hand painted murals depicting scenes from Sicily and the bay of Naples set the tone. Insta perfect picture spots come alive with a vintage Fiat 500 and the Italian Food Company Vino Van. If you have a love for all things Italy, you will come to adore this home away from home. Pizza Lovers beware - the Pizza is authentic Neapolitan, the real deal without the passport.
Top review
ANABEL
Dined 3 days ago
Great food, great service and teh three layer chocolate cake was amazing !!!
A photo of First Flight Island Restaurant & Brewery restaurant
4.5
4.5 (1459)
$30 and under
Seafood
Key West
About the restaurant
First Flight Island Restaurant and Brewery is located in the home of Pan Americans office, where the first American international flight ticket Key West- Havana, Cuba was bought on October 28th 1927. The restaurant features a beautiful garden dining area nestled under the canopies of 2 Strangler Figs, an inside dining room with Pan American memorabilia and an indoor- outdoor crash bar made from an airplane wing.This is also the birthplace of the Southernmost Brewery in the States where 3 flagship and seasonal beers are made by Brewmaster Andrew Koennecke. The restaurant menu focuses on locally sourced seafood, house brew braised dishes and fresh seasonal ingredients. The menu changes throughout the year by Executive Chef Ben Schneller who supplements tradition with an island twist.
Top review
JessieVIP
Dined 5 days ago
Beautiful outdoor seating and great atmosphere. The food was delicious. My son is in flight school so it was the perfect spot.
A photo of Yellowfin Bar & Kitchen restaurant
4.5
4.5 (53)
$31 to $50
Seafood
Key West
About the restaurant
Seafood sourced right from our marina, a char-grilled filet, or your own catch cooked right here? You’ve come to the right place. Executive Chef Yeni Mendoza and Yellowfin Bar & Kitchen celebrates flavors native to the Florida Keys while seamlessly blending them with the culinary influences and cooking styles of the Caribbean. Live music Fridays-Sundays. Enjoy your experience with us in our air-conditioned dining room, or marina-side shaded patio.
We look forward to your visit with us.

Top review
Craig
Dined on May 6, 2025
First visit to Yellowfin. The setting is first class and the staff was friendly and attentive. The Short Rib entree was the best I've had in the Keys. We will definitely return!
A photo of Salt + Ash at Hawk's Cay restaurant
4.4
4.4 (82)
$31 to $50
Farm-to-table
Duck Key
About the restaurant
Salt+Ash is a bold new dining experience by Chef Jeremy Ford, rooted in the vibrant connecton between land, sea and fire. This truly farm-to-table concept celebrates the raw beauty of natural ingredients, expertly charred and delicately seasoned with the essence of the ocean. With a curated yet effortless coastal aesthetic, Salt + Ash offers a space where bohemian charm meets refined craftsmanship, inviting guests to savor every flavor and texture that tells the story of its surroundings. Here, the elements are not just inspiration, they're the foundation.

Top review
Lauren
Dined 4 days ago
Jacob Michael Dale Beaty along with our waiter Omar, truly made the night very special. They were very attentive. The Service was impeccable! The food was spectacular! A night to remember. Will definitely be back.
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