Diners' Choice: Lively restaurants in Midtown

OpenTable

Updated June 05, 2025

Looking for restaurants that have the most vibrant bar scenes in Midtown? You’re in the right place. Each month, OpenTable analyzes nearly 2 million global diner reviews from the past four months. We sort the results by location and category to help you discover new favorite restaurants. It's a great partnership: you reserve, eat, and review. We listen...and deliver the results for all to benefit. Enjoy!

Truffles - St. Louis

4.9

4.9 (1424)

$31 to $50

Contemporary American

Clayton

About the restaurant

"Truffles has always managed that elusive balance of refinement and relaxed casualness...” Sauce, 8/2011

“This is a top-tier eatery. The kitchen is reinvigorated and inventive…” STL Magazine, 5/2011.

Truffles strives to produce a menu that easily fuses rustic and contemporary American cooking. With simplicity and seasonality as our guide, house-made specialties such as pasta and salumi are prepared fresh every day and are complemented by choice selections of locally sourced and raised meats, seafood and inventive sides. The Truffles menu begins in the fields, rivers and farms of the Midwest and our award-winning wine list features wines from every corner of the earth. We bring the best flavors of the season direct to your plate.

Top review

CarolynVIP

Dined 3 days ago

A friend and I very much enjoyed our drinks and dinner. David was a great waiter. We loved the beet salad and Tortellini. There were many tempting menu items. The noise level was vibrant, but fun.

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4.8

4.8 (2312)

$30 and under

Italian

Clayton

About the restaurant

Café Napoli is a family owned restaurant, established in 1989 by Tony and Kathy Pietoso. Quickly becoming a success, they moved the small basement restaurant to a larger location at the corner of Forsyth and Bemiston in the heart of Clayton. In 2003, sons Ande and Kye expanded their family restaurant by adding Bar Napoli, a swank cocktail lounge. A few years later, Napoli Reserve was added onto Bar Napoli allowing for private event space and an additional bar and lounge for the weekends. After years of a flourishing business, Kathy and Tony decided to take their ventures West to Town and Country where they opened their second location, Napoli2, managed by Ande. Kye has taken the reigns from his father and is now the front man for the 8,000 square foot establishment in Clayton. Café Napoli and Bar Napoli have recently undergone a face lift inside and out. Inside the kitchen, Executive Chef from Napoli2 Jon Berger was recently added to the team, bringing fresh ideas and innovation to the regional Italian specialties.

Top review

MichaelVIP

Dined 2 days ago

After 35 years, Cafe Napoli remains reliably good and reliably enjoyable. There's nothing else quite like it. Great food. Great service. Great atmosphere.

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Louie's Wine Dive - Saint Louis

4.8

4.8 (507)

$31 to $50

Wine Bar

Clayton

About the restaurant

Louie's Wine Dive is an unpretentious wine bar where guests can try an assortment of wine and some delicious food to go with them. Come check out our wine board with rotating specialty wines and cocktails. Monday is all day happy hour and we do brunch on Saturday and Sunday. Thank you to all of our wonderful guests who make this place amazing. Please call to make a reservation for a party of 5 or more and limited reservations are available on Thursday, Friday and Saturday nights. Walk ins are always welcome!

Top review

PatVIP

Dined on May 15, 2025

Had a great lunch here. The food was great and atmosphere perfect

Oceano Bistro - Clayton

4.7

4.7 (3704)

$31 to $50

Seafood

Clayton

About the restaurant

Welcome to Oceano Bistro, St. Louis premiere fresh fish bistro.

Our chefs, in partnerships with fishermen, farmers, and food artisans have searched the world's seas to bring the St. Louis area what is enjoyed by those who are living on the coast. We then pair it innovative and exciting fresh local producers and flavor combinations certain to dazzle every discerning palate at prices that are a great value for a great catch.

Top review

Viridiana

Dined 1 day ago

Food was delicious and the ambience was very pleasant!

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4.7

4.7 (724)

$31 to $50

American

Rock Hill

About the restaurant

Join us for a Night out on the corner of Manchester and Mcknight. Inside seating available. Please call 314-473-1221 to book a Party over 6 People.

Top review

Nick

Dined on Jun 6, 2025

Overall, great experience. Live music was a little loud, hard to hear others at our table.

Beyond Sweet

4.6

4.6 (392)

$50 and over

American

The Loop

About the restaurant

Beyond Sweet Kitchen + Bar is St. Louis' newest vibe.

Top review

Alecia

Dined on May 17, 2025

Although a tornado has come through and destroyed this place, it is hands down my favorite restaurant in St. Louis. From the music, to the food. I love everything about this place. Hoping it’s rebuilt.

MoMo Coffee Champagne Kitchen

4.6

4.6 (25)

$30 and under

American

Rock Hill

About the restaurant

We want to bring a different type of fun to the corner of Manchester and McKnight. COFFEE, MIMOSAS, BLOODY MARYS AND GOOD FOOD
Locally Sourced / Crafted for Fun.
The owners of The Mud House, have opened a new breakfast-and-lunch spot next to Hangar in Rock Hill. Momo’s chef is Jesse Mills, a former sous chef at the Tavern and at Hangar. Both Mills and the Sedlaks believe in using the highest quality products throughout the menu, such as farm eggs from Buttonwood Farms. That’s what sets Momo’s aside from other breakfast places. You can see and taste the difference, both in the standard dishes and on the sandwiches containing eggs.

The Momo restaurant’s tagline is “coffee-champagne-kitchen,” which hallmarks of a fun brunch. You can grab a regular breakfast or lunch, or you can crank it up with brunch-based cocktails. Momo is about coffee and cocktails and just happens to serve really good food. The restaurant is open is open for breakfast and lunch daily from 7 a.

Top review

Laura

Dined on May 10, 2025

Nice patio, good wait staff, good food and good drinks.

High Bar Clayton Rooftop

4.5

4.5 (53)

$31 to $50

Tapas / Small Plates

Clayton

About the restaurant

High Bar pays homage to the high standards and aspirations of Clayton’s business professionals. Inspired by the rigorous bar exam—a symbol of dedication and achievement—High Bar stands as a beacon for those who strive for excellence. With its industrial-chic design and panoramic skyline views, it is the perfect setting in which to sip a cocktail and enjoy sophisticated American-style cuisine crafted from locally sourced ingredients.

High Bar provides a space for meaningful connections and memorable moments, reflecting the precision and creativity of the community. Here, the elevated standards of Clayton's professionals and residents are mirrored in every detail, raising the bar for rooftop dining experiences.

Top review

JillSVIP

Dined 7 days ago

Beautiful view, good drinks, and a perfect night. I would recommend sitting outside if weather permits

Herbie's

4.4

4.4 (2476)

$30 and under

American

Clayton

About the restaurant

Herbie's is an American restaurant and bar inspired by the food & atmosphere of the French bistro as well as the cuisines of Italy, Asia, and the coastal American South. Our focus is on seasonal dishes with local ingredients, featuring rotating menus and daily specials with something to satisfy every palate. Renowned for our welcoming hospitality and gorgeous dining rooms & patios, we strive to make every guest feel at home, whether here for a business meeting, an intimate dinner, or any other occasion!

We accept reservations online & over the phone. For parties larger than 6 guests, please email reservations@herbies.com with your name, party size, date, time, phone number, and any additional requests.

To book an event, private room, or catering, please visit our website Herbies.com/private-events and fill out a contact form & a member of our team will respond promptly!

We look forward to serving you soon!

Top review

LindaVIP

Dined 2 days ago

Delicious food and a great value! Ate on the patio, which was lovely!

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Popular dish

Morel Pasta

Cafe La Vie

3.8

3.8 (229)

$31 to $50

French

Clayton

About the restaurant

Welcome to Cafe la Vie located inside the Le Meridien Hotel in Clayton!

Indulge yourself in the wonderous French European style cuisine created by our amazing team of culinary artists or a signature cocktail poured by our talented bartenders. Our spacious 7,400 sq. foot restaurant is open for breakfast, lunch, Sparkling Hour (our version of happy hour) and dinner in the heart of downtown Clayton.

Cafe la Vie offers dishes highlighting European classics with local St. Louis flavors in a warm and inviting environment.

Top review

Erica

Dined 4 days ago

The service from Matthew was excellent. We had a very relaxing meal and the food was delicious - the baked brie as a shared appetizer and the campanelle a la vodka and short ribs for entrees.

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