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Sassafras Southern Bistro, Greenville, SC

Sassafras Southern Bistro

4.8 (3622)
$30 and under
Southern
103 N Main St #107, Greenville, SC 29601

Make a reservation

2 people
7:30 PM
Booked 49 times today

About this restaurant

  • Good for special occasions
  • Charming
  • Neighborhood gem
Located in the heart of downtown Greenville, South Carolina, Sassafras Southern Bistro serves an eclectic menu of American cuisine with a truly Southern influence. Menu items include steak, fresh seafood, salads, and amazing desserts. Sassafras Southern Bistro has a full bar featuring local beers on tap and an extensive wine selection both by the glass and by the bottle.



Start out your meal at Sassafras Southern Bistro with one of their amazing appetizers like the spicy pork tenderloin or the famous blue crab and pepper-jack nachos. Choose from entrees like the raved about shrimp and grits or the filet with house made pimento. Some vegetarian and gluten free options are available upon request.

Additional information

  • Dining style
    Casual Dining
  • Price
    $30 and under
  • Cuisines
    Southern, American
  • Hours of operation
    Mon–Thu 5:00 pm–9:00 pm Fri 5:00 pm–9:30 pm Sat 4:30 pm–9:30 pm
  • Phone number
  • Payment options
    AMEX, Discover, Mastercard, Visa
  • Dress code
    Casual Dress
  • Neighborhood
    Greenville
  • Cross street
    Main Street and Coffee Street
  • Parking details
    Parking is available in the Richardson Street parking garage that is conveniently located just a few steps away and is free to park on the weekends!
  • Public transit
    Parking garage is located at 66 Richardson Street. Once you park your car walk out of the parking garage and walk right into the open area. You will see Sassafras here, we have the green awning!
  • Additional
    Bar/Lounge, Beer, BYO Wine, Cocktails, Corkage Fee, Full Bar, Gluten-free Options, Happy Hour, Non-Smoking, Patio/Outdoor Dining, Patio/Outdoor Dining, Private Room, Wheelchair Access, Wine

What 3,622 people are saying

Sassafras Southern Bistro reviews from people who’ve dined at this restaurant. Based on recent rating.

Overall ratings and reviews

Reviews can only be made by diners who have eaten at this restaurant

4.8
4.8 based on recent ratings
  • 4.8Food
  • 4.9Service
  • 4.7Ambience
  • 4.7Value

NoiseModerate

Loved For

  • South Carolina

    Best Service

  • South Carolina

    Best Value

  • South Carolina

    Southern

  • Greenville

    Best Overall

  • Greenville

    Best Service

  • Greenville

    Best Value

  • Greenville

    Most Booked

Review summary

AI-generated from verified diner reviews
Sassafras Southern Bistro charms diners with its "great service and food," offering a warm, inviting atmosphere perfect for celebrations. The menu features Southern flavors with a modern twist, and the staff's attentiveness enhances the dining experience. Known for generous portions and reasonable prices, it's a Greenville favorite.
3,622 Reviews
  1. Paul

    South Carolina4 reviews

    3.0

    Dined 1 day ago

    1. Overall 3
    2. Food 5
    3. Service 5
    4. Ambience 1
    Noisy. Made extra noisy by a waitress and her friends talking very loudly at the table behind us.

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  2. John VIP

    South Carolina65 reviews

    5.0

    Dined 1 day ago

    1. Overall 5
    2. Food 5
    3. Service 5
    4. Ambience 5
    Sassafras has been our steady choice for years because it never disappoints. The food, service, staff, ambience and location are all ideal. The she crab soup was so good I wanted to ask them to bring it in a gallon container and the seafood trio blackened was amazing. Got the Brussels sprouts this time and they are the best I’ve ever had so please don’t change that recipe. My wife said it best, “the staff at Sassafras makes me feel like we’re old friends stopping by to eat.”

    Is this helpful?

  3. Stephanie

    Greensboro / Winston Salem / Highpoint1 review

    5.0

    Dined 1 day ago

    1. Overall 5
    2. Food 5
    3. Service 5
    4. Ambience 5
    Everything was excellent…ambience, service, and food! And all for a great price!

    Is this helpful?

  4. Martin

    Washington, D.C. Area6 reviews

    5.0

    Dined 2 days ago

    1. Overall 5
    2. Food 5
    3. Service 5
    4. Ambience 4
    Really nice experience, great food in a pleasant environment, very good staff.

    Is this helpful?

  5. patrick

    South Carolina3 reviews

    5.0

    Dined on June 26, 2025

    1. Overall 5
    2. Food 5
    3. Service 5
    4. Ambience 5
    Great service and food. I love the value provided each time I dine there.

    Is this helpful?

  6. Leah

    Chicago / Illinois2 reviews

    3.0

    Dined on June 25, 2025

    1. Overall 3
    2. Food 2
    3. Service 5
    4. Ambience 3
    The server was great. Perhaps this restaurant is better suited to meat. Our fish was over cooked. I did not eat it. The Fried Green tomatoes were fine.

    Is this helpful?

  7. Brooke

    South Carolina1 review

    4.0

    Dined on June 24, 2025

    1. Overall 4
    2. Food 4
    3. Service 5
    4. Ambience 2
    We LOVE Sassafras and go multiple times a year for dinner, as well as for our anniversary every year. We also ALWAYS bring friends and out of town guests to Sassafras because we love it so much. We had fantastic service last evening, as usual. And the food was excellent, overall. However, the only part regarding the food that was not top notch was that there was WAY too much pepper/Montreal seasoning on my filet. I had to scrape it continuously to try to get it off and eventually I was able to eat it. I could not even taste the meat bc it just tasted like pepper. We also always love Sassafras because of the ambiance. Last night we were put in a room we have never been sat in. (It was the room furthest from the door). It was SUPER loud (I am not sure if the flooring was different in this room to make it loud?....it was tile.) and the music was way too loud as well. My husband and I had to repeatedly ask each other to repeat ourselves because we could not hear one another. (We are in our 40s...so we do not have trouble hearing one another typically.) If this had been our only experience with Sassafras, we would not return. Thankfully, this was not the Sassafras we have grown to know and love and feel we just hit them on an "off" night. So, not the best anniversary dinner this year. But we will try again next year.

    1 person found this helpful

  8. BARBARA VIP

    South Carolina2 reviews

    5.0

    Dined on June 24, 2025

    1. Overall 5
    2. Food 5
    3. Service 5
    4. Ambience 5
    What a wonderful spot. We had the best time for our anniversay. Sally, our waitress, was an amazing person and wonderful. The young lady at the front of the house made it quite special also. Our food was so good. If you have a special occasion to celebrate, this is the spot!

    Is this helpful?

  9. David

    South Carolina1 review

    5.0

    Dined on June 24, 2025

    1. Overall 5
    2. Food 5
    3. Service 5
    4. Ambience 5
    Sassafras is our go to for any celebration or a “just because” on a Tuesday!

    Is this helpful?

  10. Wayne

    South Carolina19 reviews

    5.0

    Dined on June 23, 2025

    1. Overall 5
    2. Food 5
    3. Service 5
    4. Ambience 4
    My wife and I dined there for our anniversary, and we had a wonderful experience. The food, the service, environment was very pleasant.

    Is this helpful?

FAQs

Sassafras Southern Bistro is rated 4.8 stars by 3622 OpenTable diners.

Yes, you can generally book this restaurant by choosing the date, time and party size on OpenTable.

  1. Home
  2. United States
  3. South Carolina
  4. Greenville
  5. Greenville

Make a reservation

2 people
7:30 PM
Booked 49 times today
Google Map for Sassafras Southern Bistro

103 N Main St #107, Greenville, SC 29601

Additional information

  • Cross street
    Main Street and Coffee Street
  • Neighborhood
    Greenville
  • Hours of operation
    Mon–Thu 5:00 pm–9:00 pm Fri 5:00 pm–9:30 pm Sat 4:30 pm–9:30 pm
  • Price
    $30 and under
  • Cuisines
    Southern, American
  • Dining style
    Casual Dining
  • Dress code
    Casual Dress
  • Parking details
    Parking is available in the Richardson Street parking garage that is conveniently located just a few steps away and is free to park on the weekends!
  • Public transit
    Parking garage is located at 66 Richardson Street. Once you park your car walk out of the parking garage and walk right into the open area. You will see Sassafras here, we have the green awning!
  • Payment options
    AMEX, Discover, Mastercard, Visa
  • Additional
    Bar/Lounge, Beer, BYO Wine, Cocktails, Corkage Fee, Full Bar, Gluten-free Options, Happy Hour, Non-Smoking, Patio/Outdoor Dining, Patio/Outdoor Dining, Private Room, Wheelchair Access, Wine
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