Enable JavaScript to run this app.
Skip to main content
OpenTable logo
  1. Home
  2. United States
  3. San Antonio

Best Neighborhood Gem Restaurants in Medical Center

Price
Cuisine
Regions
Neighborhoods
Top Rated
Dining Options
Seating Options
Accessibility

19 restaurants available nearby

How are Featured results ranked

A photo of Myron's at Alon Town Center restaurant
1. Myron's at Alon Town Center
4.9
Exceptional(4767)
Price: Expensive
• Steak • North San Antonio
Booked 16 times today
Myron’s Prime Steak House is located in Alon Towne Centre at Northwest Military Highway and Wurzbach Parkway. We are open nightly serving Chicago prime beef, the top 2% of all prime beef in the U.S. A full bar and award winning wine list are available. Owner Bill Been, known to most for his 34 years of restaurant experience In San Antonio, has created a casual but elegant dining experience and invites you to come to Myron's, and enjoy!
A photo of Selda Mediterranean Kitchen restaurant
2. Selda Mediterranean Kitchen
4.8
Exceptional(28)
Price: Moderate
• Mediterranean • North Central
Booked 3 times today
We are a Mediterranean restaurant that offers Turkish cuisine. We have a large variety of dishes that are delicious including kebabs, pide, lamacun, lamb, lots of salads and delicious desserts, including baklava. Our sister restaurant Selda Dallas is located in Dallas, Texas.
A photo of Luce Ristorante E Enoteca restaurant
3. Luce Ristorante E Enoteca
4.4
Awesome(1232)
Price: Moderate
• Italian • Medical Center
Booked 5 times today
Founded in 2006, Luce is a local favorite featuring many traditional dishes. Flavors which often bring our guests back to their best memories of Italian specialties.My goal for this restaurant to create a warm environment for all guests that is typical of a true Italian heritage. Our menu consists of many Buonincontri family recipes and recipes brought back from travel to Italy. Fresh fish, meats and produce expound throughout Luce's offerings and a focus on the finest ingredients are what make Luce special. House made Gnocchi, Italian rice balls and homemade Mozzarella are just a few examples our passion for the finest Italian food.The word Enoteca means wine library. The walls of the entire restaurant are covered with wine bottles as you would expect books to cover the walls of a library. Wine is a very important part of an experience at Luce, with over 125 choices from our wine list available to you.
A photo of Signature restaurant
4. Signature
4.9
Exceptional(2773)
Price: Very Expensive
• American • La Cantera
Booked 32 times today
*2024 Michelin Recommended*If you find yourself dreaming of the Texas Hill Country, savory comforts, spice, and the sultry depth of a fine Burgundy, you’ll be pleased to know about Signature at La Cantera Resort & Spa. The menu is straightforward and beguiling, featuring contemporary interpretations of classic dishes — fresher, brighter versions of traditional cuisine enlivened with unconventional Texas spirit. Gulf seafood conspires with Atlantic Coast oysters flown in fresh, and the Hill Country is well-represented year-round. Local and organic ingredients change the menu as the seasons peak and wane, but the constants are quality, flavor, artistry in the kitchen and a warm welcome when you walk in the door.
A photo of Meadow Neighborhood Eatery + Bar restaurant
5. Meadow Neighborhood Eatery + Bar
4.7
Exceptional(880)
Price: Expensive
• American • North Central
Meadow Neighborhood Eatery is the first restaurant by husband and wife team, Chef PJ Edwards and Lindsey Edwards. Opened September 2018, Meadow provides North Central San Antonio with a friendly, fun, warm and relaxing environment to enjoy dinner, brunch and lunch with family and friends. Our menus change frequently as we work closely with local farmers and ranchers to provide our guests with a truly Seasonal Texas Southern dining experience. A beautiful patio with a large wood burning fireplace is perfectly cozy during the cooler evenings. With a large dining room available for up to 60 people and a more intimate space in our private dining room for groups of up to 30 people, we Have the perfect space for your next party. Join us for date night or a brunch with friends and family and enjoy our ever changing truly Seasonal menu.
A photo of Biga on the Banks restaurant
6. Biga on the Banks
4.9
Exceptional(5880)
Price: Very Expensive
• Contemporary American • Downtown
Booked 13 times today
Overlooking the San Antonio River Walk since 2000, Bruce Auden’s Biga on the Banks continues to charm San Antonio foodies and Alamo City visitors with its constantly-changing new American menu featuring the best ingredients South Texas has to offer.It has been said that Bruce Auden has “put San Antonio on the culinary map” but this Chef is just getting started. The Biga menu features fresh caught fish like Mahi Mahi, True American Red Snapper and Ahi Tuna. Main stays on the menu usually include Hill Country Venison and Bandera Quail, Grilled Australian Rack of Lamb and Roasted Bell & Evans Chicken.The dining room is modern with a casual-well informed style of service.The wine list is eclectic and broad with hundreds of labels and the full bar offers craft cocktails.Biga on the Banks has a versatility about it. If you’re looking for a come-as-you-are impromptu bite, a celebratory dinner with family or a working dinner with business colleagues, Biga fits your needs.
A photo of Paloma Blanca Mexican Cuisine restaurant
7. Paloma Blanca Mexican Cuisine
4.7
Exceptional(1283)
Price: Moderate
• Mexican • Alamo Heights
Booked 17 times today
Paloma Blanca Mexican Cuisine is a neighborhood gem, consistently praised for its authentic Mexican dishes and excellent service. Reviewers rave about the 'excellent food', 'exceptional ambience', and 'superb' service. One even calls it a 'gem of a place'. The restaurant's 'beautiful patio' and 'expansive outdoor seating' are also noted as standout features. It's a favorite among locals, often described as a 'favorite restaurant in town'.
A photo of Boiler House at Pearl restaurant
8. Boiler House at Pearl
4.7
Exceptional(2175)
Price: Expensive
• Contemporary Southern • Downtown
Booked 6 times today
Boiler House at Pearl is a true Texas original. Situated in the historic Pearl Brewery complex on the San Antonio River Walk, this wine-centric restaurant occupies the former “boiler house” which powered the adjacent brewery. Lead by Executive Chef Alberto "Beto" Gutierrez, the menu focuses on grilled items from local farms and markets, with a focus on “Texas ranch-style” cuisine. These delicacies are paired with extraordinary wines from around the world (available by the glass, bottle and “to-go”), full bar, live music and a casual yet energetic atmosphere. The unique list of wines boasts some of the lowest prices in the area.The restaurant incorporates various private dining areas suitable for private or corporate functions and an expansive outdoor patio area where guests can enjoy dining alfresco. We can host groups anywhere from 9 up to 290 guests in our unique, flexible private event spaces.
A photo of Primo's restaurant
9. Primo's
4.8
Exceptional(50)
Price: Moderate
• Italian • Downtown
Booked 13 times today
PRIMO'SItalian Cuisine-Handmade Pasta's & Pizza's-Brunch - Lunch - Dinner-Covered Patio Seating
A photo of Ambler - Texas Kitchen + Cocktails restaurant
10. Ambler - Texas Kitchen + Cocktails
4.5
Awesome(613)
Price: Moderate
• Contemporary American • Downtown
Booked 12 times today
Inspired by Texas’ deep-rooted history of cattle ranches, Ambler Texas Kitchen + Cocktails serves as a culinary tribute to its beloved Lone Star State.Ambler, true to its character, is as bold in flavor as it is in design. The restaurant’s subtle masculine-yet-approachable interiors gives way to the bright and cheerful ambiance of San Antonio’s iconic Riverwalk. Offering vibrant flavors and jaw-dropping views 7 days a week for breakfast, lunch and dinner. Ambler is located on the lobby river-level of Hotel Contessa, a 265 all-suite destination property situated on the banks of the San Antonio River at 306 West Market Street. For more information or to make reservations, please visit Ambler online at amblersanantonio.com or call (210) 298-8040.
‘About the restaurant’ descriptions have been generated using an artificial intelligence model comprised of OpenTable proprietary data that has not been independently verified by OpenTable. The content is presented as-is, for informational purposes only.

See what locals rave about

From verified diners like you
From verified diners like you

Explore OpenTable

Discover
OpenTable
  • About Us
  • Blog
  • Careers
  • Press
More
Our sites
Businesses
  • Restaurant Management Solutions
  • Restaurant Reservation Software
  • Restaurant Marketing Software
  • Restaurant Event Software
  • OpenTable For Restaurants
  • OpenTable For Restaurant Groups
  • Restaurant Resources
  • OpenTable Pricing & Plans
Join us on
  • Privacy Policy
  • Terms of Use
  • Cookies and Interest-Based Ads
  • Do Not Sell or Share My Personal Information
  • Cookie Preferences
Copyright © 2025 OpenTable, Inc. 1 Montgomery St Ste 500, San Francisco CA 94104 - All rights reserved.
OpenTable is part of Booking Holdings, the world leader in online travel and related services.
Booking Logo
Priceline Logo
KAYAK Logo
Agoda Logo
OpenTable Logo