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Best Southern American Restaurants in Winston-Salem

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20 restaurants available nearby

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A photo of Mozelle's restaurant
1. Mozelle's
4.9
Exceptional(2992)
Price: Moderate
• Southern american • Winston-Salem
Booked 50 times today
Mozelle’s Fresh Southern Bistro in Winston-Salem offers an authentic American dining experience with a delightful Southern twist. Known for its “superb Southern cooking,” Mozelle's uses the "finest and freshest ingredients" to craft dishes that leave a lasting impression. Diners rave about the fried chicken, shrimp and grits, and the "divine tomato pie," which are all standout favorites. The cozy, lively atmosphere and attentive service enhance the dining experience, providing a welcoming vibe that draws patrons back time and again. With its "exceptional food and service," Mozelle’s is truly "a gem" in the heart of Winston-Salem, perfect for both everyday dining and special occasions.
A photo of Sage & Salt Bistro restaurant
2. Sage & Salt Bistro
4.7
Exceptional(543)
Price: Expensive
• Southern american • Winston-Salem
Booked 16 times today
Sage & Salt Bistro in Winston-Salem is a must-visit for aficionados of Contemporary American cuisine. Guests rave about the "fantastic food" and "outstanding meal and service," highlighting the restaurant's ability to blend traditional flavors with modern flair. Diners have been particularly impressed by the expertly cooked steaks and the creative twists on classic dishes, like the "best risottos" paired with scallops. The attentive staff and warm ambiance, often complemented by live jazz, create a dining experience that feels both special and inviting. Whether celebrating an anniversary or simply enjoying a night out, Sage & Salt promises a memorable culinary journey.
A photo of Rooster's A Noble Grille restaurant
3. Rooster's A Noble Grille
4.7
Exceptional(2213)
Price: Expensive
• Southern american • Winston-Salem
Booked 35 times today
Rooster's A Noble Grille in Winston-Salem proudly showcases the best of American cuisine with an unwavering commitment to quality and authenticity. Founded by North Carolina chef Jim Noble, the restaurant thrives on the belief that "simple food is harder to execute," ensuring each dish is a masterpiece crafted from locally sourced ingredients. Diners rave about the "outstanding service" and "exceptional food," with favorites like the spit-roasted chicken cooked over an open fire. The atmosphere is both welcoming and refined, making it perfect for any occasion. With consistently rave reviews, Rooster's promises an unforgettable dining experience steeped in authentic American flavors.
A photo of The Old Fourth Street Filling Station restaurant
4. The Old Fourth Street Filling Station
4.7
Exceptional(1558)
Price: Expensive
• Southern american • Winston-Salem
Booked 19 times today
The Old Fourth Street Filling Station in Winston-Salem is a beacon of authentic American cuisine, celebrated for its inviting atmosphere and exceptional dishes. Diners consistently rave about the "perfectly cooked steak" and "absolutely delicious burgers," making it a must-visit for any food enthusiast. The restaurant's signature Shrimp and Grits have won over many, praised for their "amazing flavor." Whether enjoying a casual meal or celebrating a special occasion, this neighborhood favorite never disappoints. The outdoor patio dining experience, enhanced by charming string lighting, adds a unique touch to every visit. It's no wonder patrons declare it their "favorite restaurant in Winston-Salem!"
A photo of Bernardin's Restaurant at the Zevely House restaurant
5. Bernardin's Restaurant at the Zevely House
4.7
Exceptional(1838)
Price: Moderate
• Southern american • Winston-Salem
Booked 28 times today
Bernardin's Restaurant at the Zevely House in Winston-Salem is a shining beacon of Contemporary American cuisine, celebrated for its “rich and tasty” flavors and impeccable execution. Nestled in a charming historic house, the atmosphere is both cozy and elegant, perfect for a special occasion or a delightful date night. The menu is diverse, offering unique dishes like the highly-praised Lobster Lobster and Filet Mignon, each cooked to perfection. Guests rave about the attentive and friendly service, with standout mentions of staff members like Josh and Katie, ensuring a memorable dining experience. Discover why Bernardin’s is a cherished gem in Winston-Salem.
A photo of Jeffrey Adams on Fourth restaurant
6. Jeffrey Adams on Fourth
4.7
Exceptional(1999)
Price: Expensive
• Southern american • Winston-Salem
Booked 11 times today
Jeffrey Adams on Fourth in Winston-Salem is a beacon of exceptional Steakhouse cuisine, celebrated for its impeccable quality and authenticity. "The filet was perfectly done," raves one diner, highlighting the mastery in steak preparation that sets this restaurant apart. Guests consistently praise the "fantastic selection" of menu offerings, from hearty steaks to delectable seafood risottos, ensuring a delightful experience for all palates. The wood-fired grill imparts a distinctive smoky flavor, enhancing the succulent taste of each steak. With an inviting atmosphere and attentive service, Jeffrey Adams on Fourth is poised to impress, making it a must-visit for steak enthusiasts.
A photo of Milner's American Southern restaurant
7. Milner's American Southern
4.7
Exceptional(2358)
Price: Expensive
• Southern american • Winston-Salem
Booked 9 times today
Milner's American Southern in Winston-Salem is a culinary gem that proudly celebrates the essence of Low Country cuisine. Renowned for its "wonderful family-owned southern elegance vibe," this restaurant masterfully blends Southern American classics with contemporary culinary techniques. Diners rave about the "perfectly seasoned grouper" and "best collards in town," showcasing the authentic flavors of the region. With live jazz on Sunday nights and a "cool atmosphere," Milner's creates a dining experience that is both comforting and sophisticated. The dedication of Brother Chefs John and Buddy to sourcing the freshest local ingredients ensures every dish is a delightful homage to Low Country tradition.
A photo of Spotted Cow Steakhouse restaurant
8. Spotted Cow Steakhouse
4.6
Exceptional(314)
Price: Moderate
• Southern american • Winston-Salem
Booked 10 times today
At Spotted Cow Steakhouse in Winston-Salem, the steak experience is nothing short of exceptional. This cozy and inviting boutique steakhouse is renowned for its top-quality cuts, with the filet mignon and ribeye taking center stage. Diners rave about the "steak cooked to perfection," exuding rich, buttery flavors that elevate their dining experience. The staff's genuine hospitality and attentiveness enhance the atmosphere, making every meal memorable. Guests frequently highlight the "perfectly cooked" steaks and generous portions, ensuring a satisfying and gratifying visit. If you're seeking authentic steak cuisine with a warm, family-friendly vibe, Spotted Cow Steakhouse is a must-visit destination.
A photo of Six Hundred° restaurant
9. Six Hundred°
4.7
Exceptional(684)
Price: Expensive
• Southern american • Winston-Salem
Booked 11 times today
At Six Hundred°, located in the historic Bailey Powerplant in Winston-Salem, the Prime Rib is nothing short of extraordinary. Known for its chef-driven menu, this upscale dining establishment offers a Prime Rib experience that is both authentic and sublime. The culinary team ensures that each cut is “cooked perfectly,” achieving the ideal temperature every time, as noted by satisfied diners. The ambiance enhances the dining experience, with patrons relishing the “phenomenal” service and the opportunity to watch chefs at work. With glowing reviews applauding its “outstanding” food and service, Six Hundred° is the ultimate destination for Prime Rib enthusiasts.
A photo of Betty on Burke restaurant
10. Betty on Burke
4.8
Exceptional(177)
Price: Moderate
• Southern american • Winston-Salem
Booked 23 times today
Nestled in the heart of downtown Winston-Salem, Betty on Burke is a fresh and exciting addition to the city’s thriving dining scene. From the team behind Mozelle’s, a beloved local favorite, Betty on Burke brings its own unique flair, offering an inviting atmosphere where exceptional food and hospitality take center stage.Step inside and be transported by a stylish, bamboo-wrapped space that feels like a hidden gem just off bustling Burke Street. Our menu celebrates bold, approachable flavors with an elevated twist, designed to delight locals and visitors alike. Whether you’re indulging in a leisurely dinner or sharing small plates with friends, every dish is crafted to create memorable moments.As a locally owned gem with deep ties to the community, Betty on Burke is proud to carry on the legacy of excellence that Mozelle’s has established. Join us for an unforgettable dining experience that perfectly balances fun, flavor, and charm—right in the heart of Winston-Salem.
‘About the restaurant’ descriptions have been generated using an artificial intelligence model comprised of OpenTable proprietary data that has not been independently verified by OpenTable. The content is presented as-is, for informational purposes only.

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