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Best Comfort Food Restaurants in Medical Center

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9 restaurants available nearby

A photo of Whiskey Cake - San Antonio restaurant
1. Whiskey Cake - San Antonio
4.7
Exceptional(4229)
Price: Moderate
• Comfort food • La Cantera
Booked 152 times today
Whiskey Cake - San Antonio is a gem in American cuisine, offering an authentic farm-to-table experience that truly delights the senses. Nestled in La Cantera, this restaurant is celebrated for its innovative approach to New American comfort food, where "everything is absolutely wonderful." The menu features locally sourced ingredients, ensuring fresh and delectable dishes like the "amazing" Mac and Cheese with duck fat breadcrumbs. Guests rave about the infamous whiskey cake, a must-try dessert that perfectly encapsulates the restaurant's unique charm. With a warm and inviting atmosphere, Whiskey Cake offers not just a meal, but an unforgettable culinary journey.
A photo of Ambler - Texas Kitchen + Cocktails restaurant
2. Ambler - Texas Kitchen + Cocktails
4.2
Awesome(569)
Price: Moderate
• Comfort food • Downtown
Booked 13 times today
Ambler - Texas Kitchen + Cocktails in Downtown San Antonio is a standout destination for cocktail enthusiasts. Nestled along the picturesque Riverwalk, this cocktail bar dazzles with its vibrant ambiance and exceptional drink offerings. Reviewers rave about the "amazing creativity in cocktail selections," with drinks like the Southern Belle and Blue Bonnet receiving particular praise. Patrons consistently highlight the "fantastic bar selection" and the welcoming, efficient bartenders who ensure every visit is memorable. Whether you're savoring a perfectly crafted margarita or exploring the diverse cocktail menu, Ambler promises an authentic and delightful experience that celebrates the spirit of Texas.
A photo of Joe's Crab Shack - San Antonio restaurant
3. Joe's Crab Shack - San Antonio
3.1
Good(24)
Price: Moderate
• Comfort food • Downtown
Booked 5 times today
Joe’s Crab Shack offers a variety of favorites from all parts of the sea and shore. From its extensive menu, guests can choose from buckets of seasonal seafood, fried shrimp platters and fish dishes, as well as options from the “mainland” that include steak, sandwiches, and chicken. Guests can indulge in over-sized and creative cocktails, such as the Shark Bite which is playfully garnished with a shark toy. Since its inception, Joe’s popularity has stemmed not only from its menu, but also its retail store. With various pieces of merchandise for purchase, including the ever-popular tie-dye T-shirt with the phrase “Peace, Love and Crabs,” Joe’s has become synonymous with the word “fun.”
A photo of Esquire Tavern restaurant
4. Esquire Tavern
4.5
Awesome(653)
Price: Expensive
• Comfort food • Downtown
Booked 21 times today
Step into a world where history and modern mix at The Esquire Tavern, San Antonio’s oldest bar on the Riverwalk. Known for its innovative Dining Bar cuisine, the Esquire masterfully combines "classic techniques and new world flavors" to create an unforgettable cocktail experience. The craft cocktails are a standout, "amazing" and expertly curated, making it a leader in San Antonio's emerging cocktail culture. With a charming vintage ambiance and a vibrant atmosphere, it's the perfect spot for a relaxed meal or a lively night out. Whether you're a local or a visitor, The Esquire Tavern promises a delightful dining adventure.
A photo of Sustenio - Eilan Hotel restaurant
5. Sustenio - Eilan Hotel
4.2
Awesome(692)
Price: Moderate
• Comfort food • La Cantera
Booked 2 times today
Enjoy the diverse flavors of South Texas at Sustenio! Local fresh produce and proteins brought in daily; with influences from Traditional Mexico, Creole and Southern Comfort foods.
A photo of Bazille – Nordstrom La Cantera restaurant
6. Bazille – Nordstrom La Cantera
4.9
Exceptional(100)
Price: Moderate
• Comfort food • La Cantera
Booked 6 times today
Bazille – Nordstrom La Cantera is a delightful destination for authentic American cuisine that beautifully combines bold flavors with classic bistro favorites. Located on level 2 inside Nordstrom at The Shops at La Cantera, this hidden gem offers a chic and inviting atmosphere that's perfect for gathering with friends. Diners rave about the "wonderful meal and wonderful service," and praise the "delicious burger" as one of the best they've ever had. With expertly crafted brick-oven pizzas, fresh salads, and tempting housemade desserts, Bazille ensures a "pleasant dining experience" with its consistently good food and friendly, attentive staff.
A photo of Maggiano's - San Antonio restaurant
7. Maggiano's - San Antonio
4.7
Exceptional(4024)
Price: Moderate
• Comfort food • Northwest
Booked 94 times today
Maggiano's - San Antonio is a shining star of authentic American cuisine, nestled in the vibrant Northwest neighborhood. This beloved spot, with its warm and inviting atmosphere, offers a true taste of American comfort food, delightfully intertwined with Italian flair. Guests rave about the "excellent food and service," with standout dishes such as the rigatoni D and filet mignon medallions. The generous portions and consistently delicious meals keep patrons returning, while the attentive service from staff like "Austin" and "Spencer" ensures every visit feels special. Ideal for any occasion, Maggiano's promises a memorable dining experience that captures the essence of American culinary tradition.
A photo of Sugar Factory - San Antonio restaurant
8. Sugar Factory - San Antonio
3.5
Very Good(500)
Price: Expensive
• Comfort food • Downtown
Booked 27 times today
Sugar Factory - San Antonio is a dessert lover's paradise, nestled in the vibrant Downtown area. Known for its "insane milkshakes" and over-the-top treats, this hotspot delivers an exceptional dessert experience that is both visually stunning and delectably indulgent. Guests rave about the "rainbow brite insane milkshake" and the "peanut butter chocolate insane milkshake," highlighting their colossal size and delightful flavors. The restaurant's high-energy ambiance, complemented by friendly staff and chic decor, ensures every visit is a memorable one. Perfect for celebrations, Sugar Factory promises a "fun and delicious" adventure, making it a must-visit for anyone with a sweet tooth.
A photo of Cover 3 - San Antonio restaurant
9. Cover 3 - San Antonio
4.5
Awesome(57)
Price: Moderate
• Comfort food • North Central
Booked 11 times today
Cover 3 - San Antonio is a top-notch destination for sports enthusiasts and food lovers alike. Nestled in the vibrant Stone Oak neighborhood, this acclaimed Sports Bar boasts a lively atmosphere with "plenty of TVs to catch the game on" and an inviting ambience. Known for its award-winning Mac N Cheese and wings, Cover 3 takes pride in crafting dishes with the freshest ingredients. Diners rave about the "absolutely great meal and super service," making it a perfect spot for any occasion. Whether you're enjoying a game or indulging in their inventive American fare, Cover 3 promises an unforgettable experience.
‘About the restaurant’ descriptions have been generated using an artificial intelligence model comprised of OpenTable proprietary data that has not been independently verified by OpenTable. The content is presented as-is, for informational purposes only.

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