Enable JavaScript to run this app.
Skip to main content
OpenTable logo
  1. Home
  2. United States
  3. San Antonio

Best Cocktail Bars in Medical Center

Price
Regions
Neighborhoods
Top Rated
Dining Options
Seating Options
Accessibility

10 restaurants available nearby

How are Featured results ranked

A photo of Haywire - La Cantera restaurant
4.5
Awesome(460)
Price: Expensive
• Cocktail Bar • La Cantera
Booked 124 times today
Haywire - La Cantera in San Antonio is redefining the Cocktail Bar experience with its exceptional collection of highly allocated whiskeys and inventive cocktail creations. Guests rave about the "Vaquero and haywire old-fashioned," describing them as "top-notch" and perfect for an upscale night out. The rustic yet elegant atmosphere complements the expertly crafted drinks, creating a warm and inviting setting for any occasion. The attentive staff ensures a memorable visit, with one review highlighting a bartender who was "perfect" and contributed to a "relaxed but elegant" atmosphere. Haywire's cocktail offerings promise an unforgettable taste of Texas hospitality.
A photo of Chama Gaucha - San Antonio restaurant
4.9
Exceptional(6780)
Price: Very Expensive
• Cocktail Bar • Stone Oak
Booked 143 times today
Chama Gaucha in San Antonio is a standout destination for Cocktail Bar enthusiasts, offering an array of expertly crafted drinks that perfectly complement its renowned Brazilian steakhouse experience. Located in the vibrant Stone Oak neighborhood, this establishment has received glowing reviews for its "well-made cocktails" that are as delightful as their succulent meats. Patrons frequently praise the bar staff's "friendly and knowledgeable" service, ensuring each cocktail is tailored to perfection. Whether enjoying pre-dinner drinks or winding down with a nightcap, Chama Gaucha’s Cocktail Bar promises an exceptional experience that elevates any visit to this acclaimed dining hotspot.
A photo of Anaqua Garden Bar restaurant
4.8
Exceptional(37)
Price: Moderate
• Cocktail Bar • Downtown
Booked 7 times today
Nestled in the heart of downtown San Antonio, Anaqua Garden Bar offers a serene escape with its lush surroundings and impeccable Japanese Speciality cuisine. The restaurant delivers "excellent food and drinks," making it a standout destination for lovers of authentic Japanese flavors. Guests rave about the "sushi tacos and ceviche," highlighting the innovative fusion that elevates traditional recipes. The ambiance is described as a "chill lounge, garden vibe," perfect for indulgent evening getaways. With attentive staff who provide "great recommendations" and a menu that boasts delicacies like the "elote lobster," Anaqua Garden Bar promises an unforgettable dining experience.
A photo of Full Belly Cafe & Bar - Sonterra restaurant
4.5
Awesome(1028)
Price: Moderate
• Cocktail Bar • North San Antonio
Booked 15 times today
Full Belly Cafe & Bar in North San Antonio is a delightful destination for Contemporary American cuisine, renowned for its scratch-made brunch, breakfast, and lunch offerings. Diners rave about the "absolutely divine" food that's "fresh, flavorful, and expertly prepared," from the lobster eggs Benedict to the irresistible brown butter cinnamon roll. The restaurant's chef-driven approach highlights the authenticity of its Contemporary American dishes, featuring fresh breads and pastries that "feed your soul." With a vibrant atmosphere and exceptional service, Full Belly Cafe & Bar promises an unforgettable dining experience that keeps guests returning time and again for more culinary delights.
A photo of Ambler - Texas Kitchen + Cocktails restaurant
4.4
Awesome(611)
Price: Moderate
• Cocktail Bar • Downtown
Booked 2 times today
Ambler - Texas Kitchen + Cocktails in Downtown San Antonio is a standout destination for cocktail enthusiasts. Nestled along the picturesque Riverwalk, this cocktail bar dazzles with its vibrant ambiance and exceptional drink offerings. Reviewers rave about the "amazing creativity in cocktail selections," with drinks like the Southern Belle and Blue Bonnet receiving particular praise. Patrons consistently highlight the "fantastic bar selection" and the welcoming, efficient bartenders who ensure every visit is memorable. Whether you're savoring a perfectly crafted margarita or exploring the diverse cocktail menu, Ambler promises an authentic and delightful experience that celebrates the spirit of Texas.
A photo of Brenner's on the River Walk restaurant
4.7
Exceptional(434)
Price: Moderate
• Cocktail Bar • Downtown
Booked 21 times today
Brenner's on the River Walk in San Antonio offers a quintessential American dining experience that beautifully marries tradition with elegance. With roots tracing back to 1936, Brenner's is renowned for its commitment to authentic American flavors and exceptional quality. Guests rave about its "phenomenal" dishes, especially the American Wagyu and the delectable bacon-wrapped shrimp. The restaurant's picturesque setting along the River Walk adds to its charm, providing breathtaking views from both indoor and balcony seating. Patrons consistently highlight the "excellent" service, noting that it enhances their dining experience, making Brenner's a must-visit for anyone seeking top-tier American cuisine.
A photo of Hugman's Oasis restaurant
4.5
Awesome(88)
Price: Moderate
• Cocktail Bar • Downtown
Booked 1 time today
Hugman's Oasis in Downtown San Antonio offers an exceptional Lounge experience that transports diners to a "tropical paradise" right in the heart of the city. Known for its vibrant, tiki-themed ambiance and unique drink offerings, this establishment is a true gem for cocktail enthusiasts. The Secret Santa Sippin’ event has received rave reviews, with visitors praising the "great ambiance" and "amazing drinks." Guests appreciate the friendly and attentive service, ensuring an unforgettable visit. Whether it's enjoying a signature mai tai or sharing delightful food bites with friends, Hugman's Oasis promises a fun and festive escape that diners won’t want to miss.
A photo of Scuzzi's Italian Restaurant restaurant
4.7
Exceptional(1137)
Price: Moderate
• Cocktail Bar • North San Antonio
Booked 4 times today
Scuzzi's Italian Restaurant in North San Antonio stands out as a premier Cocktail Bar destination, offering an exceptional experience for cocktail enthusiasts. Diners rave about the "excellent cocktails," seamlessly complementing the restaurant's rich Italian offerings. The bar staff, like Jerry, receive accolades for their attentiveness and ability to craft customized drinks that cater to individual preferences. With a vast wine list and a selection of "perfect" bar drinks, Scuzzi's ensures every visit is memorable. Whether it's a smoked old-fashioned or a mango martini, the cocktails are crafted with precision, elevating any dining occasion into a celebration. Visit Scuzzi's for an unforgettable cocktail experience!
A photo of Little Rhein Prost Haus restaurant
4.0
Excellent(126)
Price: Moderate
• Cocktail Bar • Downtown
Little Rhein Prost Haus is a standout Cocktail Bar nestled in the historic La Villita Village in downtown San Antonio. Guests rave about its "phenomenal drinks" and vibrant atmosphere, making it a must-visit spot on the River Walk. The exquisite hand-crafted cocktails are a highlight, complementing the lively Texas country ambiance and stunning river views. Patrons are enchanted by the "amazing live entertainment" and the delightful experience of sipping colorful cocktails while enjoying the best sunsets in the southern USA. With its unique blend of German design and Texas charm, Prost Haus offers an authentic and memorable cocktail experience.
A photo of Crockett Tavern restaurant
3.6
Very Good(129)
Price: Moderate
• Cocktail Bar • Downtown
Booked 2 times today
Nestled in the heart of San Antonio's historic district, Crockett Tavern offers an unparalleled Cocktail Bar experience that captures the essence of Texas hospitality. Revered for its "excellent cocktails" and vibrant atmosphere, this charming venue is a must-visit for those seeking authenticity and flair. Guests rave about the "delicious" drinks, with many claiming they serve "the best margaritas" in town. The bar's ambiance, enriched by live music and a storied setting, creates an inviting space perfect for unwinding after exploring the historic Alamo. With attentive service and a fun, energetic vibe, Crockett Tavern promises a memorable cocktail journey.
‘About the restaurant’ descriptions have been generated using an artificial intelligence model comprised of OpenTable proprietary data that has not been independently verified by OpenTable. The content is presented as-is, for informational purposes only.

See what locals rave about

From verified diners like you
From verified diners like you
OpenTable
  • About Us
  • Blog
  • Careers
  • Press
More
Businesses
  • Restaurant Management Solutions
  • Restaurant Reservation Software
  • Restaurant Marketing Software
  • Restaurant Event Software
  • OpenTable For Restaurants
  • OpenTable For Restaurant Groups
  • Restaurant Resources
  • OpenTable Pricing & Plans
Join us on
  • Privacy Policy
  • Terms of Use
  • Cookies and Interest-Based Ads
  • Do Not Sell or Share My Personal Information
  • Cookie Preferences
Copyright © 2025 OpenTable, Inc. 1 Montgomery St Ste 500, San Francisco CA 94104 - All rights reserved.
OpenTable is part of Booking Holdings, the world leader in online travel and related services.
Booking Logo
Priceline Logo
KAYAK Logo
Agoda Logo
OpenTable Logo