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Diners' Choice: Seafood restaurants in South Carolina

OpenTable

Updated January 05, 2025

Looking for restaurants with the best overall Seafood cuisine in South Carolina? You’re in the right place. Each month OpenTable analyzes more than 400,000 new diner reviews. We sort the results by category to help you discover new favorites. It's a great partnership: you reserve, eat, and review. We listen...and deliver the results for all to benefit. Enjoy!

A photo of Charlie's Coastal Bistro (L'etoile Verte) restaurant

Charlie's Coastal Bistro (L'etoile Verte)

4.9

4.9 (5374)

$31 to $50

Seafood

Hilton Head Island

About the restaurant

Focusing predominately on fresh local seafood with a French, Lowcountry flare, Charlie’s is the place for good food, good wine and unforgettable memories all enjoyed in a quaint French country atmosphere.

A Savannah native, Charlie Golson’s interest in the French language and culture took him to Paris. After a long stint in the fast paced hotel kitchens of Washington DC, he was ready to move back closer to home. It was at that time he was able to open up a one room French bistro. The restaurant has grown over the years, but the ‘Green Star’ remains steadfast in offering the finest ingredients the Low country has to offer with a menu that is hand written daily. Resort Casual.

Top review

L

Lincoln

Dined 2 days ago

Charley's is the place to go for a special occassion.

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A photo of Bread Pudding Crème Anglaise of a restaurant

Bread Pudding Crème Anglaise

A photo of Caramel Cake of a restaurant

A photo of Cobb Salad of a restaurant

A photo of Park Avenue Oyster Bar & Grill restaurant

Park Avenue Oyster Bar & Grill

4.8

4.8 (369)

$30 and under

Seafood

Aiken

About the restaurant

Park Avenue Oyster Bar & Grill specializes in seasonal cuisine, emphasizing regional seafood dishes. On the second floor, you will discover our elegant event spaces and refined bar and lounge area.

Top review

K

Kathryn

Dined 5 days ago

Back again for the Mahi which is still outstanding. The calamari is ALWAYS to die for. The 5 oz beef filet was perfectly cooked. Mussels were great, too! Another great experience with fabulous service. We'll definitely be back!

A photo of The Establishment restaurant

The Establishment

4.8

4.8 (2672)

$50 and over

Seafood

Downtown Charleston

About the restaurant

Everything at The Establishment begins with well-sourced ingredients from sea and field. Through developing relationships with local farmers and fishermen, our ingredients will be consistently seasonal, fresh, and pure. Chef Elliott Howells' menu will always reflect a clean, focused, and balanced approach, delivering a selection of thoughtful and refined cuisine.

Located in Charleston’s historic French Quarter a few blocks away from Rainbow Row, Charleston City Market, and Waterfront Park, The Establishment features an award-winning wine cellar, over 150 bourbon and whiskey offerings, and a lively bar scene complete with daily happy hour. We feature Live Music every Friday and Saturday starting at 8:00 PM, featuring multiple local artists performing an array of musical genres. Our private dining rooms are perfect for birthdays, anniversaries, graduations, or business meetings. We look forward to hosting you for a casual night out or an elevated dining experience.

Top review

A

Ann

Dined 4 days ago

My friends and I had a wonderful evening! We’ve been friends since the 6th grade and enjoyed catching up on things…

A photo of The Pearl restaurant

4.8

4.8 (2882)

$30 and under

Seafood

Bluffton

About the restaurant

Bringing to Old Town Bluffton a bright, fresh take on the dining experience, The Pearl Kitchen & Bar will please your palate with the freshest of ingredients prepared in a manner that will excite, entice, and keep you coming back for more.

Top review

P

peterVIP

Dined 3 days ago

The Pearl never fails to give a great dining experience.

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A photo of Shrimp + Grits of a restaurant

A photo of Peach + Banana Bread Pudding of a restaurant

Peach + Banana Bread Pudding

A photo of Grouper Casino of a restaurant

A photo of Red Fish - Hilton Head restaurant

Red Fish - Hilton Head

4.7

4.7 (5606)

$31 to $50

Seafood

Hilton Head Island

About the restaurant

Red Fish specializes in excellent seafood and steaks. A recipient of Wine Spectator Magazine's Best of Award of Excellence since 2001, Red Fish offers over 1300 wines from around the world for you to choose in our retail shop to enjoy with your meal (with a small corkage fee) or to take home.

Top review

G

George

Dined 2 days ago

Our server, Jenn, was attentive and knowledgeable. White wine was well chilled and served properly with the amazing flounder special. Carrot cake is a great finish to a great meal.

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A photo of Blackened Grouper of a restaurant

Blackened Grouper

A photo of Filet Mignon of a restaurant

A photo of Chilean Sea Bass of a restaurant

Chilean Sea Bass

A photo of Clark's Seafood and Chop House restaurant

Clark's Seafood and Chop House

4.8

4.8 (3567)

$30 and under

Seafood

Little River

About the restaurant

The ultimate in Myrtle Beach Chophouse dining. Clark’s is comfortable yet sophisticated and soaks up the beautiful Coquina Harbour for the perfect backdrop to delicious dining.

Clark’s offers only USDA Choice steaks. Our awe inspiring 14 oz. New York Strip, 9 oz. Filet Mignon, and Prime Rib are all served charred and bursting with prime aged flavor. Seafood is fresh and local, with a twist of seafood favorites which include oysters, shrimp, scallops and fresh catch of the day.

Our bar menu includes an extensive wine list which features a wide array of wines by the glass. Specialty martinis and cocktails and great cuisine take center stage at this scenic Little River restaurant. Clark’s Seafood and Chop House is at the top of the restaurant list for locals and Grand Strand visitors. Whether you come for lunch or dinner, we’re sure you will come back again and again.

Top review

H

Hersey

Dined 3 days ago

We got prime rib and filet steaks cooked perfectly. Calamari was excellent The shecarb soup was excellent. Only complaint is the croissants should have been warm.

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A photo of Filet Mignon of a restaurant

A photo of Prime Rib Sandwich of a restaurant

Prime Rib Sandwich

A photo of New York Strip of a restaurant

A photo of Amen Street Fish + Raw Bar restaurant

Amen Street Fish + Raw Bar

4.7

4.7 (5101)

$30 and under

Seafood

Downtown Charleston

About the restaurant

Amen Street Fish & Raw Bar opened in 2009, reviving the former Amen name of Cumberland Street and restoring this historic corner. The new renovation stays true to the beauty of the original 1800's architecture while creating a comfortable atmosphere for contemporary life.

Located at 205 East Bay Street in the heart of the historic district this Charleston seafood restaurant offers both indoor and outdoor dining all within walking distance of the local Market and the Charleston Harbor.

The menu includes a variety of seafood dishes such as oysters, clams and shrimp in addition to an ever growing raw bar menu. Amen Street supports Charleston's local fishing industry with market fresh fish.

We are open for lunch and dinner. Walk-ins are welcome and reservations are accepted as well.

Top review

A

Angela

Dined 3 days ago

The oysters were best I’ve had in a while. Very sweet. Our server, Joshua, was attentive, friendly and prompt My flounder was excellent- perfectly seasoned and prepared so there was a crunchy edge. Highly recommend

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A photo of Shrimp & Grits of a restaurant

A photo of Fried Oysters of a restaurant

A photo of Baked Oysters of a restaurant

A photo of Alexander's Restaurant & Wine Bar restaurant

Alexander's Restaurant & Wine Bar

4.8

4.8 (3559)

$31 to $50

Seafood

Hilton Head Island

About the restaurant

Alexander’s, an upscale seafood restaurant and long-time Hilton Head Island favorite on the dining scene since 1977. It features seasonally-inspired cuisine, locally-caught seafood and many locally-sourced ingredients.

Our menu pays tribute to many classic lowcountry and Alexander’s favorites such as Seafood Pasta, Shrimp and Grits, and Wiener Schnitzel. Reservations are highly encouraged. Alexander’s offers dinner nightly from 5:00 PM-9:00 PM with seasonal early dining from 5:00 PM-5:45 PM.

Top review

D

DougVIP

Dined on Jan 4, 2025

Large party to celebrate a wedding. Everything was wonderful. Michele was a rock star making everything perfect.

A photo of Long Island Cafe- Isle of Palms restaurant

Long Island Cafe- Isle of Palms

4.6

4.6 (1963)

$31 to $50

Seafood

Isle of Palms

About the restaurant

Located in Isle of Palms, Long Island Café offers a menu full of American cuisine with a focus on fresh, local seafood. The restaurant has a full bar and offers dinner, lunch and Sunday Brunch.

Top review

S

Suzy

Dined 2 days ago

Everyone had an excellent meal and the service was great.

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A photo of Crab Stuffed Shrimp of a restaurant

Crab Stuffed Shrimp

A photo of Pan Fried Flounder of a restaurant

Pan Fried Flounder

A photo of Hot Fish Club restaurant

4.6

4.6 (2320)

$30 and under

Seafood

Garden City/Murrells Inlet

About the restaurant

The original Hot and Hot Fish Club was founded in the late 1700’s by the planters of All Saints Parish. The social club was dedicated to epicurean pursuits; gourmet food, strong drinks and festive times. The first club was said to be on Drunken Jack Island, located just a few miles south from here. Members of the original club described their past time spent on the island as the “happiest hours of their lives.” The Club was dismantled and finally laid to rest after the Civil War. An ever shifting sand bar off the coast of Huntington Beach State Park is all that remains of the original site. The Hot Fish Club today is located in the oldest existing restaurant building on the Grand Strand. Hot Fish Club remains a favorite gathering place today for discriminating locals and is open to everyone seeking Great Food, Great Drink, and Lively Conversation, in the spirit of those earlier revelers. We pride ourselves on our personal service and our desire to satisfy each guest.

Top review

M

Mindy

Dined 5 days ago

Delicious food!! Service on point and the view is priceless

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A photo of Seafood Platter of a restaurant

Seafood Platter

A photo of Seafood Cioppino of a restaurant

Seafood Cioppino

A photo of She Crab Soup of a restaurant

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