Rx Restaurant

4.7
815 reviews
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$30 and under
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Southern
Located in the Castle Street Art District in Wilmington, NC, Rx Restaurant and Bar is here to serve the best local ingredients around. Our chef is committed to bringing fresh food to your table, so the menu changes daily based on what he can find locally. Parking is free on Castle Street as well as in the parking lot diagonal from us on 5th and Castle!
Dining Style
Casual Dining
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Cuisines
Southern
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Hours of operation
Tue–Sat 5:00 pm–9:00 pm
Sun 10:00 am–2:00 pm
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Phone number
(910) 399-3080
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Payment options
AMEX, Diners Club, Discover, MasterCard, Visa
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Dress code
Casual Dress
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Executive chef
James Doss
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Neighborhood
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Cross street
421 castle st
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Parking details
Parking is free on Castle Street as well as in the large parking lot diagonal from the restaurant!
Additional
Bar/Lounge, Beer, BYO Wine, Cocktails, Corkage Fee, Full Bar, Gender Neutral Restroom, Gluten-free Menu, Non-Smoking, View, Weekend Brunch, Wheelchair Access, Wine
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RR
1 review
Dined 6 days ago
Overall 5food 5service 5ambience 4

The service, atmosphere and food quality are excellent at Rx. Having everything fresh and locally sourced makes this a true winning restaurant in Wilmington.

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MG
Miami
12 reviews
Dined on December 4, 2018
Overall 5food 5service 5ambience 5

Great quaint restaurant

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ZF
Wilmington
1 review
Dined on December 2, 2018
Overall 5food 4service 5ambience 5

My husband and I went for date night, and it was perfect. Great food, great atmosphere. Love farm to table. I love the unique, seasonable choices for the food as well as drinks. We will be back!

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HS
1 review
Dined on December 1, 2018
Overall 4food 3service 4ambience 3

We usually love coming to Rx but this time with the new menu there where practically zero options for vegetarians. I ended up having only cheese grits as my dinner. Very disappointed considering the price point and reputation of this restaurant.

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LD
Charlotte
2 reviews
Dined on November 24, 2018
Overall 5food 5service 5ambience 4

Great restaurant. Ambiance and food were perfect. I would strongly recommend it.

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WR
Wilmington
2 reviews
Dined on November 24, 2018
Overall 4food 4service 5ambience 3

First visit to Rx was enjoyable.
From our welcome by hostess, Morgan, and special menu labelled Anniversary, we were made to feel very welcome. We were seated in a relatively quiet area as requested.
Miguel, our server, is the BEST that we have encountered in Wilmington. He made our Anniversary meal quite an event to remember! Extremely attentive, professional, genuinely friendly and skilled in describing entrees and ensuring that beverages and our meal items were served at appropriate intervals.
Our appetizer of clams and sausage was tastefully prepared and quite enjoyable. Entrees at Rx are creatively unique and tasty and the duck and the grouper meals were no exception. We finished the evening with a delicious cup of pumpkin cheesecake.
Will certainly return to Rx and would enjoy a broader selection of seafood entrees and wine by the glass on our next visit.

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OT
Birmingham
4 reviews
Dined on November 23, 2018
Overall 5food 5service 5ambience 5

Wonderful place to eat with friends or family! Delicious food. Miguel provided great service! Menus even wished Happy Birthday for our occasion!

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IO
Dallas
3 reviews
Dined on November 21, 2018
Overall 5food 5service 5ambience 5

We went the night before Thanksgiving, so the restaurant was quiet. The food was great as was the service. My only recommendation is they need to offer BIGGER biscuits... their biscuits are delicious but a tease.

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Raleigh
2 reviews
Dined on November 17, 2018
Overall 5food 5service 5ambience 5

This restaurant is always excellent, food and service both.

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GA
Washington DC
4 reviews
Dined on November 15, 2018
Overall 5food 5service 5ambience 5

Had a phenomenal time at Rx! I drove down from DC to visit a friend. I don’t like to cook, but I love good food and trying local restaurants wherever I go. Rx was hands down the best place I went to in Wilmington. We wanted to relax and catch up. We didn’t feel rushed at all and told our server, Amanda, that we wanted to try several things and paced them out. Nice wine list, too. She was so pleasant, fun and knowledgeable about the food. She called in the sommelier when I had a question about the wine list ... she was delightful as well.
We were debating whether to get the hickory smoked wings at such a cute, farm-to-table restaurant, but Amanda told us we wouldn’t be disappointed. They were soooo delicious. We finished them off and then quietly stuck our fingers in the bowl to swipe up the extra sweet and sour sauce ... they were that good! Bottle that sauce! We had the deviled eggs, too. They were good, too, but the wings were the star appetizer.
I had Kyle’s Baby Lettuces salad next. Again, a delicious round. Everything in was tasted fresh and matched well. My friend got a different salad. She liked it, too.
For my main, I got the pork shoulder/pork confit dish with cubes sweet potatoes. It was really, really flavorful. My friend got the shrimp and grits. She thought they were great, but when she tried my dish she said I out ordered her because the flavors in the pork dish were amazeballs.
I couldn’t resist ordering the radishes in brown butter with pumpkin seeds. Tasty and unusual side dish... we loved ‘em!
Seriously, best restaurant in Wilmington. Delicious, fresh, creative. Not pretentious but just hip enough for any age, because it’s all about the food and drink.
Thank you to the chef, kitchen and restaurant staff!

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M
New York Area
5 reviews
Dined on November 11, 2018
Overall 5food 5service 5ambience 5

We had a wonderful brunch on Sunday. The food was delicious and the staff was very welcoming and happy to serve us. We were relaxed and not rushed. A great experience!

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OT
San Francisco
3 reviews
Dined on November 11, 2018
Overall 5food 5service 3ambience 5

Food was really good, but I knew that from previous visits. Server was just o.k. Nice enough guy, just not the best.

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B
Raleigh
18 reviews
Dined on November 10, 2018
Overall 5food 5service 5ambience 4

Two couples had dinner prior to the theater. Table was ready when we arrived, Vincent took good care of us.
Food was delicious, hot and served promptly.
Will go back again.

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J
1 review
Dined on November 10, 2018
Overall 5food 5service 5ambience 5

Rx was one of the best culinary experiences of my life. As self-proclaimed "Foodies," my wife and I are always on the lookout for restaurant gems in our area. We found Rx by way of a friend's recommendation, and decided to try it on a date night dinner before we say the musical, "The King and I." From the outside, Rx doesn't look very impressive. It is located in an old pharmacy building on the fringe of Downtown Wilmington. Once you walk through the door, you are transported to an inviting place with amazing service and farm to table excellence. Everything is scratch made from locally sourced farms. The chef's attention to detail is unmatched, and the service is outstanding. We had Miguel, who catered to our every need as if we were the only table in the restaurant. We enjoyed a quiet meal, but felt comfortable enough to talk with our neighboring table about their delicious selections. We shared a starter of Crispy Pork Terrine, Lusty Monk Mustard, Rx Hot Sauce, and Pickles. It was delicious. We then shared the Chicken Fried Egg, Arugula, Somerset Beets, Holly Grove Chevre, with Kat’s Honey Vinaigrette. Such a creative way to display a soft boiled egg on a salad. For dinner, I had the NC Duck, Morgan’s Sweet Potatoes, Bok Choy, Meg’s Apples, Chicken of the Woods, with Sorghum. Absolutely the best duck I have ever eaten. My wife had the NC Shrimp, Guilford Grits, Rx Sausage, Morgan’s Mushrooms, Peppers, Tomatoes, and Herbs. She rates restaurants based on their shrimp and grits. Rx is top on her list! We finished the evening with a chocolate stout cake, bourbon ice cream, and caramel pop corn, and a pumpkin cheesecake with salted caramel and pumpkin seed brittle. From start to finish, everything was exquisite. Be prepared to spend some money, but the experience is worth every penny.

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TB
Wilmington
1 review
Dined on November 7, 2018
Overall 5food 5service 5ambience 5

Fantastic dinner as usual! A go-to favorite. They never disappoint.

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JI
1 review
Dined on November 4, 2018
Overall 5food 5service 5ambience 5

We celebrated our anniversary at RX on Sunday. We made our reservations on the recommendation of a friend. New to the Wilmington area we were looking for a casual restaurant with excellent food.
We were not disappointed. The menu has something for everyone. The farm to table ingredients made our choices perfect.
The staff made sure our experience as first timers was a total success. Our waiter Vincent guided us through the menu providing background on the suppliers and made several very good suggestions.
We will be recommending RX to all of our friends.

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OT
1 review
Dined on November 4, 2018
Overall 5food 5service 5ambience 5

Since moving to the Wilmington area about a year and a half ago, we have dined at Pinpoint about a dozen times and it has become our go to spot for family celebrations, New Year's and entertaining out of town guests. This visit was a family milestone birthday and as always the food was incredible and the service was impeccable. The chef had great suggestions to accommodate our youngest's allergies to dairy and wheat. We will definitely be back for casual dinners and special celebrations.

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S
Richmond
48 reviews
Dined on November 3, 2018
Overall 5food 5service 5ambience 5

Delightful evening. We had not been to RX for some time. We found this gem to exceed our expectations. The clams and broth appetizer was wonderful. Grouper and fried chicken were our entrees. Both were spectacular. Dessert and coffee completed the night. The staff, led by Amanda, were caring and comfortable. Thank you.

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DM
1 review
Dined on November 1, 2018
Overall 4food 3service 4ambience 4

Great restaurant for a date and a quiet nice dinner. The only reason I don't give it 5 stars is that my dinner wasn't great, but my date's was fantastic!

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CJ
1 review
Dined on November 1, 2018
Overall 5food 5service 5ambience 5

We had a great time. We went for our anniversary! I would highly recommend this place. We will be back.

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T
New York Area
9 reviews
Dined on November 1, 2018
Overall 4food 4service 5ambience 3

Good food, good wine, great service. A thoroughly enjoyable experience.

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JS
Wilmington
1 review
Dined on October 31, 2018
Overall 5food 5service 5ambience 5

Excellent experience!

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AM
Wilmington
7 reviews
Dined on October 31, 2018
Overall 5food 5service 5ambience 5

Brought a colleague from out of town ~ from the moment we sat down, everything was perfect. Service as always was great. We’d worked a long day & were starving. Our waiter brought biscuits& cornbread as soon as I asked!😋 Cocktails soon arrived-falling for Izzyz! Our entrees were outstanding and desserts to go were fabulous! (Chocolate coconut tart could be the best dessert I’ve had at Rx)! Rx never disappoints- thank you for making it a memorable meal for an out of town friend!

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TD
New York Area
8 reviews
Dined on October 28, 2018
Overall 5food 5service 5ambience 5

Drove from Ocean Isle Beach to eat here. Heard nothing but great things about this place! Ask for Addison as your server! Friendly, knowledgeable & adorable

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OT
Charleston
1 review
Dined on October 28, 2018
Overall 5food 5service 5ambience 5

Brunch was awesome!!! Blueberry French toast...amazing.

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CB
1 review
Dined on October 27, 2018
Overall 5food 5service 5ambience 5

Amazing food and service. Loved my experience will definitely go back.

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AM
Wilmington
8 reviews
Dined on October 25, 2018
Overall 5food 5service 5ambience 5

I hadn’t been to Rx in awhile ~ still incredible in every way! Creative cocktails and every course was better than the last!

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M
Wilmington
1 review
Dined on October 21, 2018
Overall 5food 5service 5ambience 5

Thank you so much for a memorable experience. My wife had never visited RX so I knew this was indeed the best location to brunch on our 1st year wedding anniversary. The atmosphere was perfect...the food was on point...and the staff was awesome! We had the best brunch and thank you once again for the amazing brunch. RX is the best!!

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DS
1 review
Dined on October 20, 2018
Overall 5food 5service 5ambience 5

First time at Rx. Enjoyed the meal. Happy to support community restaurants, especially ones that source from local farmers. The food was excellent. Will definitely go back soon.

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b
1 review
Dined on October 19, 2018
Overall 5food 5service 5ambience 5

My wife and I had a fantastic time at Rx. The farm to table dining options were amazing, and were expertly prepared. The waitstaff was friendly and knowledgable about their menu options. We don't have any food sensitivities, but our server and host asked if we needed any special accommodations. Our meals and drinks came out very quickly and were the perfect temperatures. We felt very well taken care of throughout the entire evening. This was one of our better dining experiences all around from start to finish. I would love to go back as soon as I can, and if I could afford it I would probably eat here once a week.

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KJ
Wilmington
1 review
Dined on October 16, 2018
Overall 5food 5service 5ambience 5

I can't say enough about the service at RX. These guys went above and beyond to make my husband's birthday special. The food was absolutely delicious - I highly recommend trying as many appetizers as possible. The seasonal trigger fish was especially good. Can't wait to come back.

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JH
1 review
Dined on October 12, 2018
Overall 5food 5service 5ambience 4

excellent fresh regional food and great service. It does get a little loud when packed but not an issue. I go here all the time

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OT
1 review
Dined on September 29, 2018
Overall 5food 5service 5ambience 5

Always a great experience at RX. Service is efficient and friendly, food and drinks are unique and delicious. One of Wilmington’s best dinner spots!!!!

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MK
Wilmington
80 reviews
Dined on September 11, 2018
Overall 5food 5service 5ambience 4

This is one of the best go to restaurants in Wilmington and area. Also some of the best wait staff and bartenders. Rick is by far one of the best.

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OT
Jacksonville
1 review
Dined on September 9, 2018
Overall 5food 5service 5ambience 5

Excellent food, great coffee and an overall fantastic experience

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MB
1 review
Dined on September 7, 2018
Overall 5food 5service 5ambience 5

Fabulous sheepshead fish cooked to perfection with fresh vegetables in a sauce so tasty we had to eat every bite of the veggies too.

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MB
Wilmington
3 reviews
Dined on September 2, 2018
Overall 5food 5service 4ambience 4

Great meal. Love this place, though the noise level can be pretty overwhelming when it is busy.

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DL
Indiana
4 reviews
Dined on September 1, 2018
Overall 3food 2service 2ambience 2

Food was microwaved but advertised as fresh. Very noisy, difficult to talk. It may have been just the day, I know they get good reviews so I would try it again.

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JL
Wilmington
8 reviews
Dined on September 1, 2018
Overall 4food 4service 5ambience 4

Love RX - my only issue with my meal was the fatty piece of pork... Flavor was great but a bit too much fat on the cut. Sides are always creative! Fish dip was tasty.

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JP
Wilmington
1 review
Dined on August 31, 2018
Overall 5food 5service 5ambience 5

Great place to entertain friends from out-of-town.

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