Enable JavaScript to run this app.
Skip to main content
OpenTable logo
  1. Home
  2. United States
  3. Philadelphia / New Jersey Suburbs
  4. Western Suburbs
  5. Radnor
Main and Vine, Villanova, PA

Main and Vine

4.3
4.3
496 Reviews
$30 and under
American
Top Tags:
Recently voted BEST NEW MAIN LINE RESTAURANT 2019, MAIN & VINE brings a piece of Northern California to the heart of Philadelphia’s Main Line. Celebrated for its diversity in taste, Northern California embraces all palates in the community it serves with an added sense of sophistication. Credited as the birthplace of the modern farm to table movement, the region resources the freshest, most natural ingredients from its own backyard, a practice that has since become a way of life by many.


While famous for producing some of the finest wines in the world, Northern California is also home to some of the top craft breweries in production today, and prides itself on creating such cocktails as the iconic gin martini and the Mai Tai just to name a few.


It is this craft and culinary union that embodies the MAIN & VINE spirit and approach. Our bistro welcomes guests to experience the best of Northern California for themselves, in a sophisticatedly hip,

Permanently Closed

This restaurant is permanently closed.

Order delivery or takeout

Additional information

  • Dining style
    Casual Dining
  • Cuisines
    American, Bistro, Californian
  • Hours of operation
    Brunch Sun 11:00 am–2:30 pm Bar Mon–Thu, Sun 4:00 pm–12:00 am Fri, Sat 4:00 pm–1:00 am Happy Hour Mon–Fri 4:00 pm–6:30 pm Dinner Mon–Thu, Sun 5:00 pm–10:00 pm Fri, Sat 5:00 pm–11:00 pm
  • Phone number
    (484) 380-3688
  • Website
    http://www.mainandvinebistro.com/
  • Payment options
    AMEX, Discover, Mastercard, Visa
  • Dress code
    Casual Dress
  • Private party facilities
    MAIN & VINE offers both Private and Semi-Private Dining room options for parties upward of 200 people. Whether for family, friends, or business, Main & Vine is the perfect location for all of your private dining needs. We offer multiple menu package options for any style of event from casual Happy Hours to formal Chef Tasting Dinners. Conveniently located in the center of the Main Line, on Lancaster Avenue and just off the 476 exit, Main & Vine also offers ample FREE parking. Please feel free to contact us at events@mainandvinebistro.com for all inquiries.
  • Location
    789 E Lancaster Ave, Ste 30, Villanova, PA 19085
  • Neighborhood
    Radnor
  • Parking details
    MAIN & VINE offers ample FREE PARKING within the Villanova Center.
  • Additional
    Bar/Lounge, Beer, Cocktails, Corkage Fee, Counter Seating, Entertainment, Full Bar, Happy Hour, Late Night, Non-Smoking, Patio/Outdoor Dining, Patio/Outdoor Dining, Private Room, Takeout, Weekend Brunch, Wheelchair Access, Wine
Gift card

Gift card

Send gift cards instantly by email or print to present in person.

Send a gift card

What 496 people are saying

Overall ratings and reviews

4.3
4.3 based on recent ratings
  • 4.3Food
  • 4.4Service
  • 4.5Ambience
  • 4.1Value

Noise • Moderate

496 Reviews

  1. PhilLA

    Philadelphia

    27 reviews

    vip
    4.0

    27 reviews

    Dined on March 13, 2020

    overall4food4service5ambience5
    They took extra precautions regarding the corona virus. Constantly wiped door knobs and menus. Servers wore gloves. Tables spaced.

    Is this helpful?

  2. ChesterCountyFoodie

    Philadelphia

    7 reviews

    5.0

    7 reviews

    Dined on March 9, 2020

    overall5food5service5ambience5
    Outstanding meal! Can't wait to go back to try other dishes.

    Is this helpful?

  3. Nadrad314

    Chicago

    55 reviews

    vip
    4.0

    55 reviews

    Dined on March 8, 2020

    overall4food4service5ambience5
    Great service. Timing of courses was perfect. Good wine and liquor selection and the martini was mixed perfectly.

    Is this helpful?

  4. Lovesitalian

    Philadelphia

    11 reviews

    vip
    4.0

    11 reviews

    Dined on March 8, 2020

    overall4food4service5ambience5
    We love Main & Vine! We started with the burrata (amazing!) and shrimp tempura (delicious!) appetizers. The black grouper is a favorite and so good. We tried the cioppino this time and were disappointed. The tomato sauce was too thick and overpowered the seafood. It also had just a straight tomato taste - nothing to enhance it such as onion, herbs or even fennel. Bland. Also, because the sauce was too thick, it really destroyed the disintegrated the crab. The biggest issue is that it was literally 90% mussels. It basically was a dish of mussels in tomato sauce. The sour dough that came with it was fantastic. Main & Vine is a favorite though and we will definitely be back - we just won't order the cioppino.

    Is this helpful?

  5. MRCP

    Philadelphia

    1 review

    5.0

    1 review

    Dined on March 6, 2020

    overall5food5service5ambience5
    Excellent experience as always with good drinks and good food. Mike took great care of us as usual!

    Is this helpful?

  6. JoyB

    Philadelphia

    26 reviews

    vip
    5.0

    26 reviews

    Dined on March 5, 2020

    overall5food5service5ambience5
    Had dinner at the bar. Wonderful, engaging bartender. Awesome evening.

    Is this helpful?

  7. OpenTable Diner

    Philadelphia

    6 reviews

    vip
    3.0

    6 reviews

    Dined on March 5, 2020

    overall3food2service4ambience4
    We went here for our 4th wedding anniversary. The food needed help. Sweet potato hummus was okay not great. Brussel sprouts lyonnaise had way to much acid. My chicken was bleeding (yes blood) and the cioppino was made with a red sauce not a broth. The devil’s chocolate cake was underwhelming. What made up for the okay food was a fantastic wine list, @lacolombecoffee coffee and great service. Also, Thursday is live music night. #mainandvinebistro #localeats #rileyeats

    Is this helpful?

  8. BradL

    Philadelphia

    43 reviews

    vip
    5.0

    43 reviews

    Dined on March 1, 2020

    overall5food5service5ambience5
    Once again Phil took great care of us.

    Is this helpful?

  9. Jerry

    Philadelphia

    60 reviews

    vip
    5.0

    60 reviews

    Dined on February 29, 2020

    overall5food5service5ambience5
    We had another fantastic meal at Main and Vine. Our waiter, Christian, introduced us to some new menu items that were delicious. The owner Jay was amicable as always And he always makes customers feel special.All in all a great dining experience!

    Is this helpful?

  10. OpenTable Diner

    Philadelphia

    47 reviews

    vip
    5.0

    47 reviews

    Dined on February 23, 2020

    overall5food5service5ambience5
    Great time always. Lauren is a great bartender and waiter!

    Is this helpful?

  11. BradL

    Philadelphia

    43 reviews

    vip
    5.0

    43 reviews

    Dined on February 23, 2020

    overall5food5service5ambience5
    Excellent brunch and once again Phil took great care of us.

    Is this helpful?

  12. JLandry

    Philadelphia

    1 review

    5.0

    1 review

    Dined on February 23, 2020

    overall5food5service5ambience5
    My family and I visited Mine and Vine for the first time on Sunday 2/23 for their Sunday Buffet brunch. From the moment we walked in, it was very clean and set up beautifully for brunch. It was reasonably priced. They had a gentlemen in there providing acoustic music, which was wonderful. I will definitely be going back again! I really wish I could remember the two gentlemen that assisted our table because they were fantastic, very attentive and extremely helpful, especially at our request of finding soy or almond milk for my niece and for finding an extra thing of fruit loops cereal for my son!

    Is this helpful?

  13. JJphila

    Philadelphia

    2 reviews

    5.0

    2 reviews

    Dined on February 19, 2020

    overall5food5service5ambience5
    Inventive food!

    Is this helpful?

  14. OpenTable Diner

    Philadelphia

    20 reviews

    vip
    5.0

    20 reviews

    Dined on February 17, 2020

    overall5food5service5ambience5
    Service was great! Food was yummy! Excited to try other items on the menu!

    Is this helpful?

  15. ChesterCountyFoodie

    Philadelphia

    8 reviews

    5.0

    8 reviews

    Dined on February 17, 2020

    overall5food5service5ambience5
    Main and Vine is our favorite restaurant on the main line!

    Is this helpful?

  16. Janasita

    Greater Boston

    27 reviews

    vip
    4.0

    27 reviews

    Dined on February 16, 2020

    overall4food5service4ambience4
    Excellent food. We were placed by the door on a very cold night so I had to wear my coat for dinner. Reservations were at 8:00 pm on a Saturday and half the items ordered were no longer available but the food that was available was excellent and perfectly prepared.

    Is this helpful?

  17. Rundje

    Philadelphia

    40 reviews

    vip
    5.0

    40 reviews

    Dined on February 16, 2020

    overall5food4service5ambience5
    Love the ambience!

    Is this helpful?

  18. SharonC

    Philadelphia

    32 reviews

    vip
    3.0

    32 reviews

    Dined on February 15, 2020

    overall3food5service2ambience3
    Slow service when it’s busy. Bar and dinner table. Really slow. Gave my appetizer to the table next to me. When I said never mind, cancel it, he brought mine out anyway, super late, and charged me. Even After I said cancel it. The table next got my app free, and I paid for mine after I canceled it. When we Arrived to the bar at 5:40. there was a total of 4 of us at the bar. Took forever to get a drink. They were too busy prepping for the night it seemed. Took forever to get the check and EVEN LONGER to get the credit card back. The place is nice, the food is good, but the service, ahhh.

    Is this helpful?

  19. OpenTable Diner

    Philadelphia

    5 reviews

    vip
    5.0

    5 reviews

    Dined on February 15, 2020

    overall5food5service5ambience5
    Phenomenal. Atmosphere was great. Staff, well trained. Food was delicious. I highly recommend Main and Vine to anyone who hasn’t been.

    Is this helpful?

  20. MichelleN

    Washington DC

    3 reviews

    5.0

    3 reviews

    Dined on February 13, 2020

    overall5food5service5ambience5
    We had a blast at the UnValentine’s Party! The band was so much fun and we will definitely be back to see them. It was a festive scene and as always the food and drinks were top notch.

    Is this helpful?

  21. Jennifer

    Philadelphia

    2 reviews

    5.0

    2 reviews

    Dined on February 13, 2020

    overall5food5service5ambience5
    Love the live music - Jontourage was amazing!

    1 person found this helpful

  22. OpenTable Diner

    Philadelphia

    7 reviews

    5.0

    7 reviews

    Dined on February 13, 2020

    overall5food5service5ambience5
    Went to M&V on Feb. 13 to enjoy some great food with friends and catch a performance by the legendary Jontourage. It turned out to be the absolute best night! Not only was the food amazing...the place was packed! The service was incredible for how busy they were. The vibe was awesome...it was the place to be on Thursday night. M&V has been having a lot of live music lately and it just adds to the already wonderful experience with the food and drinks. This is my go to place for a fun night out with friends or an intimate meal with my husband. Can’t wait to return!

    Is this helpful?

  23. TheBBC

    Charleston

    7 reviews

    5.0

    7 reviews

    Dined on February 13, 2020

    overall5food5service5ambience5
    Amazing night out with friends! Food and service were fantastic, top notch, and the live music (Jontourage Band) was awesome! I will definitely be back. Looking forward to trying brunch. Thank you MAIN & VINE for a great night!

    Is this helpful?

  24. OpenTable Diner

    Philadelphia

    1 review

    1.0

    1 review

    Dined on February 12, 2020

    overall1food4service3ambience3
    Way understaffed and sat our server with at least 9 tables from what I could observe in about a 20-30 min span. Took 25 mins to order. Then just over an hour to get the food. He tried hard. But it was just not happening. Hope they learned their lesson.

    Is this helpful?

  25. OpenTable Diner

    Poconos

    4 reviews

    4.0

    4 reviews

    Dined on February 12, 2020

    overall4food5service1ambience5
    Waiter was in a coma, and, despite 3-spaced out “reminders,” he didn’t bring our bread until my last fork of Carbonara! Brought a spectacular $400 vintage bottle of vino (98), and although I was quite happy with their corkage ($25) policy, our waiter didn’t touch it other than opening it (didn’t offer to decant) and his taking us up on our offer to taste THE best bottle in the building! Will be back, but Mike will not wait MY table ever again!

    Is this helpful?

  26. BAMRN

    Philadelphia

    17 reviews

    vip
    2.0

    17 reviews

    Dined on February 12, 2020

    overall2food2service2ambience3
    We have been to Main and Vine a few times before, and although I would not rate it as a "5" star restaurant, we have always had an above average meal. On this most recent visit, I suggested to several other friends that we come here for dinner; we were extremely disappointed in both the service and the food. The scallop special was almost too salty to eat and the appetizer crab cakes were way over-priced for the product. The hummus and Sunday Ragu were very good, as was the butternut squash soup. The rest of our entrees were just OK. The server was curt and complained every time she came to the table about how busy she was and because of the basketball game, she could not guarantee good service (we were there 2.5 hours prior to the game, so we told her no rush, that's why we were there early). She never came back to ask how the food was, so the people who ordered the scallops did not even have a chance to tell her about the salty dish, which perhaps could have been rectified. We all had a good time, despite that, but unfortunately, I doubt my 6 other friends will ever be back, which is unfortunate, because the restaurant is in a great location. Because we have been there before, I would probably try it again, but honestly, the Refectory, down the road in Villanova is a far superior choice, especially for the cost.

    Is this helpful?

  27. SharonC

    Greater Boston

    15 reviews

    vip
    5.0

    15 reviews

    Dined on February 12, 2020

    overall5food5service5ambience5
    Great Get Together Spot Great Happy Hour menu

    Is this helpful?

  28. OpenTable Diner

    Philadelphia

    2 reviews

    5.0

    2 reviews

    Dined on February 9, 2020

    overall5food5service5ambience5
    A quiet night at Main and Vine was just what the doctor ordered. My parents visited from Lancaster and we all had a lovely time. The appetizers were fantastic. We really enjoyed the calamari and wellfleet oysters. My parents ordered the grouper and I ordered the duck. My dish was a great balance of sweet and savory while the grouper was a great savory seafood delight. For dessert, while I normally like the budino, the rum raisin cannoli sundae was a lovely change of pace. Overall the selection of wine, beer, and cocktails was lovely as well. The ambiance and decor matched. I can definitely recommend an easy sunday dinner here and recommend it to all! Apparently they also do brunch with live music!

    3 people found this helpful

  29. JudiB

    Philadelphia

    1 review

    5.0

    1 review

    Dined on February 9, 2020

    overall5food5service5ambience5
    Great food and service. I really enjoyed by birthday brunch. The food was fresh, hot and delicious. I can’t wait to return, for happy hour or dinner!! I highly recommend this BRUNCH to everyone!! 👍🏼👍🏼 Jlubin

    1 person found this helpful

  30. rossken

    Philadelphia

    6 reviews

    vip
    2.0

    6 reviews

    Dined on February 9, 2020

    overall2food1service1ambience1
    The noise level is significant with music blaring away While there appear to be enough wait staff they are poorly organized The kitchen expeditor is nonexistent as entres arrive piecemeal Our side arrived 10 minutes after the entre The French fries must have been frozen as they had freezer burn The rib eye was unevenly cooked and an inferior cut

    Is this helpful?

  31. DanB

    Philadelphia

    2 reviews

    5.0

    2 reviews

    Dined on February 8, 2020

    overall5food5service5ambience5
    Great service and food. Highly recommended and will return.

    Is this helpful?

  32. CrustyCurmudgeon

    Philadelphia

    414 reviews

    vip
    5.0

    414 reviews

    Dined on February 5, 2020

    overall5food5service5ambience5
    The new may have worn off, but the vibe hasn't! It's still great and promises to remain so, after multiple fine times and meals there. Following drinks at the well stocked bar, we started with artichokes, calimari, and Brussels sprouts before tackling grouper and a burger. Everything was perfectly done, beautifully presented, and a joy to eat. The wine list is very carefully (even affectionately) put together by someone who knows what he or she is doing. There are many wonderful wines you'll rarely if ever see in restaurants around here, like the Michael David Inkblot cab franc we had and loved. With great service from a skilled, friendly staff, there's everything to love and nothing to upset.

    Is this helpful?

  33. OpenTable Diner

    Philadelphia

    20 reviews

    vip
    5.0

    20 reviews

    Dined on January 31, 2020

    overall5food5service5ambience5
    Healthy portion sizes, live music, busy atmosphere and F’n delicious!

    Is this helpful?

  34. Lauren

    Philadelphia

    8 reviews

    3.0

    8 reviews

    Dined on January 30, 2020

    overall3food4service1ambience5
    Food was great, ambiance regarding decor- great, noise level very loud but some may like an energetic setting, and lastly, I sincerely hope the glacially slow service was due to an unexpected staff shortage otherwise, service was abysmal.

    Is this helpful?

  35. SharonW

    Philadelphia

    1 review

    2.0

    1 review

    Dined on January 30, 2020

    overall2food2service2ambience3
    Not enough help. We were there for 3 hours. Food was cold

    Is this helpful?

  36. OpenTable Diner

    Philadelphia

    47 reviews

    vip
    5.0

    47 reviews

    Dined on January 29, 2020

    overall5food5service5ambience5
    Great time and very attentive waiter. Mike is an excellent waiter!

    Is this helpful?

  37. Patience123

    Philadelphia

    9 reviews

    vip
    5.0

    9 reviews

    Dined on January 29, 2020

    overall5food5service5ambience5
    Great food and atmosphere.

    Is this helpful?

  38. OpenTable Diner

    Philadelphia

    20 reviews

    vip
    5.0

    20 reviews

    Dined on January 29, 2020

    overall5food5service5ambience5
    This may be our new favorite restaurant in the area! Service was pleasurable and food was YUMMY. Excited to try Sunday brunch!

    Is this helpful?

  39. ChesterCountyFoodie

    Philadelphia

    8 reviews

    5.0

    8 reviews

    Dined on January 29, 2020

    overall5food5service5ambience5
    The food was fantastic and the service was friendly and knowledgeable! We love the atmosphere at Main and Vine and can't wait to come back to try their upcoming new menu.

    Is this helpful?

  40. OpenTable Diner

    Philadelphia

    20 reviews

    vip
    5.0

    20 reviews

    Dined on January 27, 2020

    overall5food5service5ambience5
    Fantastic experience!

    Is this helpful?

FAQs

Main and Vine offers takeout which you can order by calling the restaurant at (484) 380-3688.

Main and Vine is rated 4.3 stars by 496 OpenTable diners.

Main and Vine does offer gift cards which you can purchase here.

Permanently Closed

This restaurant is permanently closed.

Order delivery or takeout

Google Map for Main and Vine

789 E Lancaster Ave, Ste 30, Villanova, PA 19085

Additional information

  • Neighborhood
    Radnor
  • Hours of operation
    Brunch Sun 11:00 am–2:30 pm Bar Mon–Thu, Sun 4:00 pm–12:00 am Fri, Sat 4:00 pm–1:00 am Happy Hour Mon–Fri 4:00 pm–6:30 pm Dinner Mon–Thu, Sun 5:00 pm–10:00 pm Fri, Sat 5:00 pm–11:00 pm
  • Cuisines
    American, Bistro, Californian
  • Dining style
    Casual Dining
  • Dress code
    Casual Dress
  • Parking details
    MAIN & VINE offers ample FREE PARKING within the Villanova Center.
  • Payment options
    AMEX, Discover, Mastercard, Visa
  • Additional
    Bar/Lounge, Beer, Cocktails, Corkage Fee, Counter Seating, Entertainment, Full Bar, Happy Hour, Late Night, Non-Smoking, Patio/Outdoor Dining, Patio/Outdoor Dining, Private Room, Takeout, Weekend Brunch, Wheelchair Access, Wine
  • Website
    http://www.mainandvinebistro.com/
  • Phone number
    (484) 380-3688
  • Private party facilities
    MAIN & VINE offers both Private and Semi-Private Dining room options for parties upward of 200 people. Whether for family, friends, or business, Main & Vine is the perfect location for all of your private dining needs. We offer multiple menu package options for any style of event from casual Happy Hours to formal Chef Tasting Dinners. Conveniently located in the center of the Main Line, on Lancaster Avenue and just off the 476 exit, Main & Vine also offers ample FREE parking. Please feel free to contact us at events@mainandvinebistro.com for all inquiries.
Gift card

Gift card

Send gift cards instantly by email or print to present in person.

Send a gift card
Discover
OpenTable
  • About Us
  • Blog
  • Careers
  • Press
More
Our sites
Businesses
  • Restaurant reservation software
  • Industry insights
  • Hospitality resources
  • Marketing resources
  • Operation resources
  • How to open a restaurant
  • For restaurants
  • For restaurant groups
Join us on
  • Privacy Policy
  • Terms of Use
  • Cookies and Interest-Based Ads
  • Do Not Sell or Share My Personal Information
  • Cookie Preferences
Copyright © 2023 OpenTable, Inc. 1 Montgomery St Ste 500, San Francisco CA 94104 - All rights reserved.
OpenTable is part of Booking Holdings, the world leader in online travel and related services.
Booking Logo
Priceline Logo
KAYAK Logo
Agoda Logo
Rentalcars Logo
OpenTable Logo