Artisanal Cocktails - Charleston Restaurants

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Artisanal Cocktails

Artisanal {ahr-tuh-zuh-nal} adj.: Hand-crafted in limited quantities using traditional and specialty ingredients, methods and techniques resulting in superior quality.

Shake up your next dining experience with a creative cocktail crafted with homemade liquors, infusions and garnishes.

55 Restaurants Drink Lists with a Twist

How are Featured results ranked
The default order for search results reflects a number of factors, including table availability, restaurant location, search criteria, and restaurant reviews and ratings. In addition, payment made by a restaurant to OpenTable is also a factor for the relative ordering of restaurants.
photo of parcel 32 restaurant
Awesome
(295)
85% 85% Recommend
$ $ $ $
Contemporary American Downtown Charleston
Hurry, we only have 4 timeslots left!
Handcrafted cocktails, extensive wine list, and local beer available.
photo of tupelo honey - myrtle beach restaurant
Exceptional
(469)
96% 96% Recommend
$ $ $ $
Contemporary Southern Myrtle Beach
Myrtle Beach's premiere cocktail location. Enjoy a night of specialty southern libations.

Top special:

Happy Hour - $2 Domestic Beers and $4 Snacks

photo of ruth's chris steak house - columbia restaurant
Awesome
(1318)
85% 85% Recommend
$ $ $ $
Steakhouse Columbia
Featuring quality ingredients & fresh squeezed juices, unique libations are handmade to perfection.
photo of the establishment restaurant
Exceptional
(603)
93% 93% Recommend
$ $ $ $
Seafood Downtown Charleston
The Establishment serves incredible cocktails along with a diverse, expertly curated wine list.
photo of circa 1886 restaurant
Exceptional
(3467)
93% 93% Recommend
$ $ $ $
Southern Downtown Charleston
From 5PM until 7PM, guests can select from a list of wines and specialty cocktails all only $7 each.
photo of pawpaw restaurant
Awesome
(1410)
83% 83% Recommend
$ $ $ $
Contemporary American Downtown Charleston
Shh! There's a "Whisper List" of cocktails for bar patrons.
Today: Barrel-Rested Striped Pig Negroni
photo of jianna restaurant
Exceptional
(1112)
94% 94% Recommend
$ $ $ $
Italian Greenville
Hurry, we only have 3 timeslots left!
Jianna’s mixologists are always ready to present a variety of interesting handcrafted cocktails.
photo of rappahannock oyster bar - charleston restaurant
Awesome
(714)
90% 90% Recommend
$ $ $ $
Seafood Downtown Charleston
craft cocktails, local beer and an extensive wine program to appeal to every palate Cheers!

Top special:

Charleston's Best Oyster Happy Hour

photo of henrietta's - the dewberry restaurant
Awesome
(487)
80% 80% Recommend
$ $ $ $
French American Downtown Charleston
Award winning signature cocktails hand crafted by Beverage Director, Ryan Casey.
photo of boathouse at breach inlet restaurant
Awesome
(3254)
82% 82% Recommend
$ $ $ $
Seafood Isle of Palms
Hurry, we only have 4 timeslots left!
Come in & Check out our new Specialty Cocktail List!
photo of sea captain's house restaurant
Awesome
(1108)
87% 87% Recommend
$ $ $ $
Seafood Myrtle Beach
Hurry, we only have 4 timeslots left!
Delicious bar bites that tickles the taste buds as you throw a cold one down the hatch!
photo of tupelo honey - greenville restaurant
Exceptional
(1055)
92% 92% Recommend
$ $ $ $
Contemporary Southern Greenville
Enjoy a night of specialty southern libations.

Top special:

Happy Hour - $2 Off Craft Beers and $4 Snacks

photo of ombra cucina italiana restaurant
Exceptional
(2504)
95% 95% Recommend
$ $ $ $
Italian Hilton Head
The Trentino
Stoli Gala Apple, Pama liqueur, Apple Pucker,
soda, rocks

photo of frankie bones restaurant & lounge - hilton head island restaurant
Exceptional
(2447)
93% 93% Recommend
$ $ $ $
Italian Hilton Head
Hurry, we only have 2 timeslots left!
From The Dirty Dean to The Politician, our Special Martini menu will amaze you!
photo of red fish - hilton head restaurant
Awesome
(2947)
88% 88% Recommend
$ $ $ $
Seafood Hilton Head
Thursdays at Fish, REMIXology shakes things up w. original, fresh, seasonally inspired cocktails ($4) at the bar.

photo of larkin's on the river restaurant
Awesome
(2800)
90% 90% Recommend
$ $ $ $
American Greenville
House-made bitters and syrups mixed with the finest liquors make our libations one-of-a-kind!
photo of the strip club 104 a steak house restaurant
Exceptional
(1334)
97% 97% Recommend
$ $ $ $
Steakhouse Greer
Hurry, we only have 4 timeslots left!
Oaki-doki - We take our Tyger Heart honey bourbon chilled and blend with charred oak barrel smoke.
photo of the black marlin bayside grill restaurant
Awesome
(1124)
88% 88% Recommend
$ $ $ $
Seafood Hilton Head
Hurry, we only have 4 timeslots left!
Our Signature Drink "The Black Marlin Hurricane" Featured at The Hurricane Bar and The Black Marlin!
photo of michael's on the alley restaurant
Awesome
(708)
69% 69% Recommend
$ $ $ $
Steakhouse Downtown Charleston
Visit The Victor Social Club our upscale lounge featuring Ernest Hemingway themed cocktails!
photo of wiseguys steak & lounge restaurant
Awesome
(2334)
93% 93% Recommend
$ $ $ $
Steakhouse Hilton Head
Award Winning Wine List, Fantastic Bourbon and Scotch List, House Infused Liquors, and Craft Beers.
photo of firebirds wood fired grill - greenville restaurant
Exceptional
(755)
96% 96% Recommend
$ $ $ $
American Greenville
Seasonal Craft Cocktails now available. Handcrafted in harmony with the season.
photo of ruth's chris steak house - charleston restaurant
Awesome
(871)
88% 88% Recommend
$ $ $ $
Steakhouse Downtown Charleston
Featuring quality ingredients & fresh squeezed juices, unique libations are handmade to perfection.
photo of vincent chicco's restaurant
Excellent
(739)
79% 79% Recommend
$ $ $ $
Italian Downtown Charleston
Vincent Chicco's offers it's own cozy, romantic bar with all Italian wines, perfect for date night!
photo of limoncello restaurant
Awesome
(614)
86% 86% Recommend
$ $ $ $
Italian Greenville
One of a kind craft cocktails. Happy hour Mon.-Fri. 4-6pm. Italian wine and beer selections!
photo of marleys island grille restaurant
Awesome
(1137)
93% 93% Recommend
$ $ $ $
Seafood Hilton Head
Hurry, we only have 4 timeslots left!
Are you craving the best cocktails and reasonable prices? Checkout Marley's Island Grill & Bar.
photo of aspen grille restaurant
Exceptional
(2124)
92% 92% Recommend
$ $ $ $
American Myrtle Beach
With Signature Martinis and Seasonal Cocktails, Aspen Grille is a great spot for drinks and music.
photo of 843 korean bbq & sushi house restaurant
Exceptional
(150)
92% 92% Recommend
$ $ $ $
Korean North Charleston
Soju Cocktails Galore~~ 4-7 Happy Hour & Late Night Weekends
photo of ruth's chris steak house - myrtle beach restaurant
Exceptional
(1601)
87% 87% Recommend
$ $ $ $
Steakhouse Myrtle Beach
Featuring quality ingredients & fresh squeezed juices, unique libations are handmade to perfection.
photo of bistro 90 restaurant
Exceptional
(828)
98% 98% Recommend
$ $ $ $
Steakhouse Myrtle Beach
We provide an extensive, seasonal and traditional variety of Artisan and Hand-Crafted Cocktails.
photo of catch 22 restaurant
Awesome
(571)
92% 92% Recommend
$ $ $ $
Seafood Hilton Head
At the Bar Only 5:00-6:30 $2.95 Bottled Beer, $3.95 Well Liquor, $4.25 Wine plus Appetizer Specials
photo of stella's bistro - simpsonville restaurant
Exceptional
(1173)
97% 97% Recommend
$ $ $ $
Southern Greenville
Join us! Mojito changes daily, Seasonal ingredients for Sangria & always smile from the bartender!
photo of collector's cafe restaurant
Exceptional
(963)
100% 100% Recommend
$ $ $ $
Mediterranean Myrtle Beach
Every Friday night we host "Ladies Night!" $4 select martinis & $4 "Vodka and" drinks till midnight!
photo of wasabi of summerville - call ahead seating restaurant
Excellent
(308)
62% 62% Recommend
$ $ $ $
Japanese Summerville
Lotus Flower coconut rum, pineapple juice, oj and blue Curacao
photo of ruth's chris steak house - downtown greenville at riverplace restaurant
Awesome
(713)
84% 84% Recommend
$ $ $ $
Steakhouse Greenville
Featuring quality ingredients & fresh squeezed juices, unique libations are handmade to perfection.
photo of hard rock cafe - myrtle beach restaurant
Awesome
(129)
85% 85% Recommend
$ $ $ $
American Myrtle Beach
Featuring our Love is Love Shake in honor of Pride Month. Available for a limited time, June 1-30.

Top special:

Happy Hour Daily 4-7PM
Happy Hour

Learn more
photo of chestnut hill restaurant
Awesome
(158)
91% 91% Recommend
$ $ $ $
American Myrtle Beach
Extensive Happy Hour every evening 4-7 PM in our lounge.
photo of fraser's tavern restaurant
Excellent
(412)
82% 82% Recommend
$ $ $ $
Bar / Lounge / Bottle Service Hilton Head
Hurry, we only have 4 timeslots left!
Choose between ten original cocktails or enjoy our signature Bourbon collection.
photo of ruth's chris steak house - greenville restaurant
Awesome
(947)
90% 90% Recommend
$ $ $ $
Steakhouse Greenville
Featuring quality ingredients & fresh squeezed juices, unique libations are handmade to perfection.
photo of crooked oak tavern restaurant
Exceptional
(40)
100% 100% Recommend
$ $ $ $
Steakhouse Conway
We carry over 40 different types of Bourbon, organic wines, and local craft beer. Happy Hour 4-6 PM
photo of restaurant 17 restaurant
Exceptional
(575)
78% 78% Recommend
$ $ $ $
American Travelers Rest
We feature our classic inspired chef-crafted cocktails following our "old world meets new" motif.
photo of cypress room - island vista resort restaurant
Awesome
(121)
81% 81% Recommend
$ $ $ $
Contemporary Southern Myrtle Beach
Happy Hour Daily from 4 to 6pm with up to 40% off on cocktails, glass wines and beer!!!
photo of crepe du jour restaurant
Excellent
(65)
85% 85% Recommend
$ $ $ $
French Greenville
We offer an all-French wine list with an inventive craft cocktail bar!
photo of romano's macaroni grill - greenville restaurant
36% 36% Recommend
$ $ $ $
Italian Greer
Enjoy hand-crafted classic and modern cocktails, perfectly paired with your favorite Italian bites.
photo of hank's seafood restaurant restaurant
Exceptional
(7977)
93% 93% Recommend
$ $ $ $
Seafood Downtown Charleston
Hurry, we only have 4 timeslots left!
Offering a Variety of Local Spirits & Brews along with a Well-Curated Wine List. This is your place!
photo of fleet landing restaurant & bar restaurant
Exceptional
(4581)
92% 92% Recommend
$ $ $ $
Seafood Downtown Charleston
Find next available

At the moment, there’s no online availability within 2.5 hours of 7:00 PM. Have another time in mind?

Check out our specially crafted martini list!
photo of stars restaurant - rooftop & grill room restaurant
Awesome
(1580)
84% 84% Recommend
$ $ $ $
American Downtown Charleston
Find next available

At the moment, there’s no online availability within 2.5 hours of 7:00 PM. Have another time in mind?

Be sure to checkout our extensive list of seasonal and artisan cocktails.

photo of poseidon-hilton head island restaurant
Awesome
(1501)
89% 89% Recommend
$ $ $ $
Seafood Hilton Head
Find next available

At the moment, there’s no online availability within 2.5 hours of 7:00 PM. Have another time in mind?

Where else can you try the Coastal Skies? Join us as we shake up some amazing Tito's Vodka drinks!
photo of page's okra grill restaurant
Exceptional
(116)
92% 92% Recommend
$ $ $ $
Southern Mount Pleasant
Find next available

At the moment, there’s no online availability within 2.5 hours of 7:00 PM. Have another time in mind?

Pages Okra Grill has now created some new and inviting drinks for all our guests.
photo of bistro toulouse restaurant
Exceptional
(763)
100% 100% Recommend
$ $ $ $
French Mount Pleasant
Find next available

At the moment, there’s no online availability within 2.5 hours of 7:00 PM. Have another time in mind?

Specialty cocktails include French Blonde, Violet Royale, Island Old Fashioned, Honey Ginger Snap
photo of leyla fine lebanese cuisine restaurant
Exceptional
(886)
92% 92% Recommend
$ $ $ $
Lebanese Downtown Charleston
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At the moment, there’s no online availability within 2.5 hours of 7:00 PM. Have another time in mind?

Our cocktails are delightful and refreshing in a variety of exotic tastes and rainbow colors .
photo of lucky rooster kitchen + bar restaurant
Exceptional
(1310)
89% 89% Recommend
$ $ $ $
Contemporary American Hilton Head
Find next available

At the moment, there’s no online availability within 2.5 hours of 7:00 PM. Have another time in mind?

Featured in The New York Times, the Brooklyn features bourbon, amaro, cherry & blood orange liqueur
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