Enable JavaScript to run this app.
Skip to main content
OpenTable logo
  1. Home
  2. United States
  3. San Antonio

Best Cozy Restaurants in Medical Center

Price
Cuisine
Regions
Neighborhoods
Top Rated
Dining Options
Seating Options
Accessibility

51 restaurants available nearby

How are Featured results ranked

A photo of Clementine restaurant
1. Clementine
4.8
Exceptional(599)
Price: Very Expensive
• Contemporary American • North Central
Booked 17 times today
At Clementine, we’re serving seasonal, innovative eats in a modern & lively atmosphere. Our team, led by John (2023 James Beard nominee for Best Chef: Texas) and Elise Russ, draws inspiration from diverse global flavors. Our ever-evolving menu guarantees fresh and exciting options, while our dishes like the White Mushroom Salad, Ricotta Cavatelli and Clementine Crunch Bar remain cherished favorites. Our beverage menu is small but mighty, carefully curated to include only the most delicious wines & beers from our absolute favorite producers expertly selected to elevate your dining experience. Want your own bottle? Our corkage fee is $35 per 750ml.Our Dining Room provides comfortable indoor seating, while the Kitchen Bar boasts an exciting vantage point overlooking our open kitchen, allowing you to witness the creation of each dish. For a change of scenery, our covered patio, is perfect for al fresco dining, complete with heaters and blankets to keep you cozy on those cool nights.
A photo of Luce Ristorante E Enoteca restaurant
2. Luce Ristorante E Enoteca
4.4
Awesome(1223)
Price: Moderate
• Italian • Medical Center
Booked 13 times today
Founded in 2006, Luce is a local favorite featuring many traditional dishes. Flavors which often bring our guests back to their best memories of Italian specialties.My goal for this restaurant to create a warm environment for all guests that is typical of a true Italian heritage. Our menu consists of many Buonincontri family recipes and recipes brought back from travel to Italy. Fresh fish, meats and produce expound throughout Luce's offerings and a focus on the finest ingredients are what make Luce special. House made Gnocchi, Italian rice balls and homemade Mozzarella are just a few examples our passion for the finest Italian food.The word Enoteca means wine library. The walls of the entire restaurant are covered with wine bottles as you would expect books to cover the walls of a library. Wine is a very important part of an experience at Luce, with over 125 choices from our wine list available to you.
A photo of Longtab Brewing Company restaurant
3. Longtab Brewing Company
4.5
Awesome(3)
Price: Moderate
• Brewery • Inner West Side
Booked 1 time today
Longtab Brewing is a veteran owned brewery and restaurant serving local, scratch-made dishes, award winning craft beer made in house, as well as a selection of Texas wines and cider. Our restaurant serves an eclectic array of dishes inspired by a mix of Belgian, German, and local Texas fare!Enjoy our famous Pork Belly Nachos which are cut, seasoned, and smoked all in house, our best selling Cubano featuring beer-braised pork shoulder and pecan-smoked ham, or our German Bratwurst Plate featuring Texas bratwurst and German potato salad. Longtab's beer selection focuses on classic beer styles with a special focus on Belgian and German styles. We offer a casual atmosphere with elevated dining as well as outdoor seating. Our space is cozy and filled with US Army Special Forces artifacts and memorabilia.
A photo of Best Quality Daughter restaurant
4. Best Quality Daughter
4.8
Exceptional(629)
Price: Moderate
• Unspecified • Downtown
Booked 89 times today
Best Quality Daughter houses a vibrant, chic décor and new, unique Asian-American menu. In 2018, chef Jennifer Hwa Dobbertin, wanting to address the sparsity of Asian-American female chefs in South Texas, developed a new concept through a series of pop-up dinners called Best Quality Daughter with fellow chef Anne Ng and artist Jennifer Ling Datchuk. Today Best Quality Daughter is located in the historic Mueller House at the Pearl Brewery. Curated by chef Jennifer Hwa Dobbertin, Best Quality Daughter's menu takes inspiration from her travels and the comfort food of her youth as a second-generation Chinese-American.
A photo of Dean's Steak & Seafood restaurant
5. Dean's Steak & Seafood
4.6
Exceptional(360)
Price: Very Expensive
• Steak • Downtown
Booked 28 times today
Embrace the unique and step into the old school at Dean’s Steak & Seafood. Adapted into a historic 19th-century schoolhouse, this classic steakhouse and bar offers an elevated menu of prime steaks, A5 Japanese and Texas wagyu, and top-quality seafood. Simply put, this one-of-a-kind steakhouse is unlike anything else in the city.If you're looking for an elevated bar experience, visit The Study at Dean's. This intimate speakeasy bar is a cocktail aficionado’s haven, ideal for those who appreciate higher touch ingredients, presentation, and ambiance. Linger over high-end cocktails and small bites in a charming atmosphere with raised banquettes, brass details, and a dedicated outdoor patio shaded under century-old live oak trees - this is the educated choice for a place to connect and unwind.
A photo of Paladar Fusion Mexico Cuba restaurant
6. Paladar Fusion Mexico Cuba
4.9
Exceptional(60)
Price: Moderate
• Mexican • Alamo Heights
Booked 4 times today
Discover a unique dining experience that marries the bold and spicy flavors of Mexican cuisine with the soulful and vibrant tastes of Cuba. Located in Alamo Heights, we offer a menu that celebrates this exciting culinary fusion. Our cozy restaurant, adorned with an elegant tropical decor, provides the perfect setting for enjoying our innovative dishes.Every dish on our menu is a harmonious blend of two rich culinary traditions. We pride ourselves on using fresh, high-quality ingredients to deliver a memorable dining experience that transports your taste buds to a world where Mexico and Cuba come together.
A photo of Supper restaurant
7. Supper
4.6
Exceptional(3245)
Price: Expensive
• Contemporary American • Downtown
Booked 45 times today
Supper is a cozy restaurant in Downtown San Antonio. Reviewers rave about the 'cozy, restorative vibes', 'warm and fresh aesthetics', and 'unique, inviting and welcoming' ambiance. The restaurant's blend of 'genial South Texas hospitality' and 'American cookery' creates a warm and friendly atmosphere, making it a favorite among locals.
A photo of Leche de Tigre Cebicheria Peruana restaurant
8. Leche de Tigre Cebicheria Peruana
4.8
Exceptional(144)
Price: Expensive
• Peruvian • Downtown
Booked 66 times today
*2024 Michelin Recommended* & *James Beard Nomination for Best Chef Texas 2025* - Leche de Tigre is a Peruvian cebichería and pisco bar in Southtown, San Antonio. Chef Emil Oliva has curated a menu that celebrates Peruvian cuisine in an authentic yet not traditional way using nikkei techniques, chifa recipes, criollo traditions, spanish and Italian influences. We invite you to experience different spaces in our restaurant. We have the greenhouse for a nice cozy space filled with plants, perfect for larger and private parties as well. Our ceviche bar where guests are able to have a much more personable experience with the chefs and the food. A Pisco bar full of talented bartenders curating amazing cocktails. Our dining room, exciting, busy, warm, and full of life. We also offer shaded front patio with a busy street and a covered back patio experience with beautiful trees surrounding us. We look forward to serving you, welcome to our home.
A photo of Bliss Restaurant restaurant
9. Bliss Restaurant
4.9
Exceptional(5080)
Price: Very Expensive
• Contemporary American • Downtown
Booked 30 times today
Bliss Restaurant is described as 'cozy' and 'quaint' by multiple reviewers. The ambiance is praised as 'thoughtfully crafted', 'intimate', and 'inviting', creating a 'relaxed yet elegant dining experience'. The decor is also highlighted as 'subdued and romantic'. Overall, it's a 'comfortable, eclectic atmosphere' that diners love.
A photo of North Italia - San Antonio restaurant
10. North Italia - San Antonio
4.6
Exceptional(1141)
Price: Moderate
• Italian • North San Antonio
Booked 51 times today
At North, we set the standard for crave-worthy by serving delicious handmade food daily. Our chefs use only the freshest ingredients to create Italian dishes that consistently satisfy. Enjoy pastas made from scratch daily. Favorites like Bolognese and Chicken Parm. And unexpected bites that go above beyond, like savory Zucca Chips and White Truffle Garlic Bread. Plus an assortment of house-made cocktails, expertly curated wine, and local craft beers that will beckon you to relax, sip and savor every moment you are here.
‘About the restaurant’ descriptions have been generated using an artificial intelligence model comprised of OpenTable proprietary data that has not been independently verified by OpenTable. The content is presented as-is, for informational purposes only.

See what locals rave about

From verified diners like you
From verified diners like you

Explore OpenTable

Discover
OpenTable
  • About Us
  • Blog
  • Careers
  • Press
More
Our sites
Businesses
  • Restaurant reservation software
  • Industry insights
  • Hospitality resources
  • Marketing resources
  • Operation resources
  • How to open a restaurant
  • For restaurants
  • For restaurant groups
Join us on
  • Privacy Policy
  • Terms of Use
  • Cookies and Interest-Based Ads
  • Do Not Sell or Share My Personal Information
  • Cookie Preferences
Copyright © 2025 OpenTable, Inc. 1 Montgomery St Ste 500, San Francisco CA 94104 - All rights reserved.
OpenTable is part of Booking Holdings, the world leader in online travel and related services.
Booking Logo
Priceline Logo
KAYAK Logo
Agoda Logo
OpenTable Logo