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Best American Restaurants in Mission District

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146 restaurants available nearby

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A photo of Curio restaurant
1. Curio
4.4
Awesome(328)
Price: Moderate
• American • Mission District
Booked 3 times today
Curio, located in the vibrant Mission District of San Francisco, offers an exceptional Contemporary American dining experience. This eclectic bar and restaurant skillfully merges regional American cuisine with a flair for the unconventional, creating a menu that delights and surprises. Reviewers rave about the “unique and flavorful” dishes, highlighting the perfectly cooked burgers and tender braised short ribs. The atmosphere is enriched by “awesome cocktails and food,” along with live music that elevates the dining experience. With excellent service and a seamless connection to the neighboring venue, The Chapel, Curio ensures a memorable night filled with culinary and cultural pleasures.
A photo of House of Prime Rib restaurant
2. House of Prime Rib
4.8
Exceptional(16245)
Price: Very Expensive
• American • Civic Center / Hayes Valley / Van Ness
Booked 208 times today
House of Prime Rib in San Francisco is a beacon of authentic American cuisine, renowned for its "iconic" status and exceptional prime rib. With 62 years of unwavering dedication, it’s no surprise that this establishment garners glowing praise from loyal patrons who rave about its "festive" atmosphere and "superb" service. Guests continually highlight the "delicious" prime rib, which is described as "massive" and "perfectly cooked," making every visit a memorable experience. The lively ambiance and the meticulous attention from the staff ensure that every meal feels like a special occasion. Truly, House of Prime Rib offers a quintessential American dining experience.
A photo of Tartine Manufactory - San Francisco restaurant
3. Tartine Manufactory - San Francisco
4.9
Exceptional(1058)
Price: Expensive
• American • Mission District
Booked 21 times today
Tartine Manufactory in San Francisco’s vibrant Mission District is a beacon of authentic American cuisine, celebrated for its mastery of artisanal bread and world-class sourdough pizza. Diners rave about the restaurant’s "outstanding" food and "fantastic" service, emphasizing the quality of its market-driven, seasonal menu. The pizzas, described as "some of the best in the city," showcase a true American culinary flair with unique toppings and a perfect crust. The atmosphere is equally inviting, with a "lovely, airy space" and a laid-back vibe that makes every visit a special occasion. Tartine Manufactory is a must-visit for anyone craving genuine American flavors.
A photo of Frances restaurant
4. Frances
4.8
Exceptional(3720)
Price: Very Expensive
• American • The Castro
Booked 23 times today
Frances, nestled in the heart of The Castro in San Francisco, is a beacon of Contemporary American cuisine, celebrated for its vibrant and innovative dishes. Chef Melissa Perello’s seasonal menu masterfully showcases "California Cuisine," emphasizing fresh, locally sourced ingredients that "speak for themselves." Diners rave about the "phenomenal" short rib and "divine" house sourdough, noting the harmonious blend of flavors that elevate each dish. The restaurant’s ambiance is described as cozy yet elegant, making it a perfect spot for special occasions. With its "exemplary" service and carefully curated wine pairings, Frances offers an unforgettable dining experience that keeps patrons returning for more.
A photo of State Bird Provisions restaurant
5. State Bird Provisions
4.7
Exceptional(3432)
Price: Very Expensive
• American • Western Addition
Booked 76 times today
State Bird Provisions in Western Addition, San Francisco, offers an extraordinary American dining experience that truly stands out. Known for its inventive "dim sum" style service, this restaurant presents a creative twist on classic American flavors. Diners rave about the "delicious, innovative, and surprising" small dishes that keep the experience fresh and exciting. With impeccable service and a lively atmosphere, patrons find themselves returning for more. The signature quail dish and the adventurous blue corn-pepita pancakes with braised bacon and coffee butter are must-tries. As one enthusiastic diner put it, "Every dish was like culinary viagra," making this a must-visit for any American cuisine enthusiast.
A photo of Starbelly restaurant
6. Starbelly
4.6
Exceptional(1645)
Price: Moderate
• American • The Castro
Booked 30 times today
Starbelly in The Castro serves an exceptional Californian cuisine experience that has diners raving about its “consistently delicious food and cocktails” and “warm, helpful, and personable” service. This urban gem brings Californian comfort food to life with a seasonal menu that harmonizes perfectly with their craft cocktails, beer, and wine. Diners can enjoy dishes like the popular corn pizza and fresh pasta amidst a lively ambiance, often described as “an oasis in the heart of the city.” The charming garden patio adds a special touch, making Starbelly a vibrant neighborhood favorite perfect for any occasion.
A photo of The Progress restaurant
7. The Progress
4.8
Exceptional(2603)
Price: Very Expensive
• American • Western Addition
Booked 49 times today
The Progress in Western Addition, San Francisco, offers a truly remarkable Californian dining experience. Celebrated for its "innovative menu" and "delicious flavors," this restaurant uses entirely local ingredients to craft dishes that highlight the essence of Californian cuisine. Guests rave about the duck, described as a "must-try" and "100% juicy and tender," alongside other inventive dishes like the seaweed noodles and Tierra vegetables masa dumplings. The ambiance is "casual and playful," providing the perfect setting for what many reviewers describe as "the best meal in SF." With excellent service and a creative menu, The Progress is an unmissable culinary gem.
A photo of Holey Moley - San Francisco restaurant
8. Holey Moley - San Francisco
new
(0)
Price: Moderate
• American • Mission District
Played up an appetite? Lucky for you, we're slinging delicious old-school sandwiches, burgers, bits and bites, and pretty much anything else you could want to keep you full on the green! If it's cocktails you're after, we've got that covered too! With our best caddies on the case, slignin' famous signatures or classic cocktails, you'll be hydrated throughout your golfing shenanigans and sure to sink many a hole-in-one!Please note, OpenTable reservations are just for dining and does not include mini golf. Mini golf reservations can be made through our website.
A photo of Wayfare Tavern restaurant
9. Wayfare Tavern
4.6
Exceptional(7989)
Price: Moderate
• American • Financial District / Embarcadero
Booked 111 times today
Wayfare Tavern, nestled in San Francisco's bustling Financial District, stands as a beacon of exemplary Contemporary American cuisine. Chef Tyler Florence masterfully crafts dishes that transport diners to an era of authentic American flavors inspired by the early 20th century. The restaurant is celebrated for its "impeccably delicious" offerings, with standout dishes like the renowned "Mary’s Fried Chicken" and "deviled eggs" that leave patrons raving. The vibrant yet cozy Victorian ambiance complements the culinary delights, making it perfect for any occasion. With "phenomenal" service and a dedication to quality, Wayfare Tavern is a must-visit destination for food enthusiasts.
A photo of The Palm Court at RH San Francisco restaurant
10. The Palm Court at RH San Francisco
4.8
Exceptional(1939)
Price: Very Expensive
• American • Potrero Hill / Dogpatch
Booked 44 times today
The Palm Court is located in RH San Francisco's Gallery at the Historic Bethlehem Steel Building. Recalling the distinctive glamour of San Francisco's Gilded Age, the stunning statement space is sheathed in Italian Calacatta gold marble and features a cascading center fountain, towering Medjool date palms and glimmering chandeliers. Adjacent to the restaurant, two luminous wine bars offer exceptional wines and Champagnes from around the world.For group dining inquiries, please email: sfhospitality@rh.com

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Discover best American restaurants in Mission District

Discover the heart of American dining in San Francisco's Mission District, where a diverse array of restaurants offers a unique take on classic American cuisine. From gourmet burgers and artisanal sandwiches to innovative takes on traditional dishes, the Mission District is a culinary hotspot that caters to all tastes. Each restaurant in this vibrant neighborhood showcases a commitment to quality, with a focus on locally sourced ingredients and creative culinary techniques. Patrons can expect not only a meal but an experience that highlights the rich, multicultural backdrop of this iconic San Francisco locale. The dining scene here is dynamic and inviting, making it a must-visit for food lovers seeking an authentic American dining experience. Whether you're in the mood for a casual eatery or a more sophisticated dining affair, the Mission District offers an array of options that promise to satisfy your palate.

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